Y0000810

Acemetacin

European Pharmacopoeia (EP) Reference Standard

Manufacturer: Sigma Aldrich

CAS Number: 53164-05-9

Synonym(S): 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid carboxymethyl ester

Select a Size

Pack Size SKU Availability Price
100 MG Y0000810-100-MG In Stock ₹ 14,072.50

Y0000810 - 100 MG

₹ 14,072.50

In Stock

Quantity

1

Base Price: ₹ 14,072.50

GST (18%): ₹ 2,533.05

Total Price: ₹ 16,605.55

grade

pharmaceutical primary standard

API family

acemetacin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc2n(c(C)c(CC(=O)OCC(O)=O)c2c1)C(=O)c3ccc(Cl)cc3

InChI

1S/C21H18ClNO6/c1-12-16(10-20(26)29-11-19(24)25)17-9-15(28-2)7-8-18(17)23(12)21(27)13-3-5-14(22)6-4-13/h3-9H,10-11H2,1-2H3,(H,24,25)

InChI key

FSQKKOOTNAMONP-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742) , PTGS2(5743)

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Description

  • General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
  • Application: Acemetacin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
  • Biochem/physiol Actions: An NSAID that specifically potentiates the cytoxicity of anthracyclines (doxorubicin, daunorubicin and epirubium). Circumvents MRP-mediated multidrug resistance.
  • Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
  • Other Notes: Sales restrictions may apply.

SAFETY INFORMATION

Pictograms

GHS06

Signal Word

Danger

Hazard Statements

H300 + H310 + H330

Precautionary Statements

P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral

WGK

WGK 3

Compare Similar Items

Show Difference

Img

Sigma Aldrich

Y0000810

European Pharmacopoeia (EP) Referen...


grade:
pharmaceutical primary standard

API family:
acemetacin

manufacturer/tradename:
EDQM

application(s):
pharmaceutical (small molecule)

format:
neat

storage temp.:
2-8°C

SMILES string:
COc1ccc2n(c(C)c(CC(=O)OCC(O)=O)c2c1)C(=O)c3ccc(Cl)cc3

InChI:
1S/C21H18ClNO6/c1-12-16(10-20(26)29-11-19(24)25)17-9-15(28-2)7-8-18(17)23(12)21(27)13-3-5-14(22)6-4-13/h3-9H,10-11H2,1-2H3,(H,24,25)

InChI key:
FSQKKOOTNAMONP-UHFFFAOYSA-N

Gene Information:
human ... PTGS1(5742) , PTGS2(5743)

Img

Sigma Aldrich

Y0000811

European Pharmacopoeia (EP) Referen...


grade:
pharmaceutical primary standard

API family:
acemetacin

manufacturer/tradename:
EDQM

application(s):
pharmaceutical (small molecule)

format:
neat

storage temp.:
2-8°C

SMILES string:
OC(=O)c1ccc(Cl)cc1

InChI:
1S/C7H5ClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)

InChI key:
XRHGYUZYPHTUJZ-UHFFFAOYSA-N

Gene Information:
__

Img

Sigma Aldrich

Y0000812

European Pharmacopoeia (EP) Referen...


grade:
pharmaceutical primary standard

API family:
bisoprolol

manufacturer/tradename:
EDQM

application(s):
pharmaceutical (small molecule)

format:
neat

storage temp.:
2-8°C

SMILES string:
OC(=O)\C=C\C(O)=O.CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1.CC(C)NCC(O)COc2ccc(COCCOC(C)C)cc2

InChI:
1S/2C18H31NO4.C4H4O4/c2*1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h2*5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+

InChI key:
VMDFASMUILANOL-WXXKFALUSA-N

Gene Information:
human ... ADRB1(153)

Img

Sigma Aldrich

Y0000813

European Pharmacopoeia (EP) Referen...


grade:
pharmaceutical primary standard

API family:
bisoprolol

manufacturer/tradename:
EDQM

application(s):
pharmaceutical (small molecule)

format:
neat

storage temp.:
2-8°C

SMILES string:
OC(=O)\C=C\C(O)=O.CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1.CC(C)NCC(O)COc2ccc(COCCOC(C)C)cc2

InChI:
1S/2C18H31NO4.C4H4O4/c2*1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h2*5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+

InChI key:
VMDFASMUILANOL-WXXKFALUSA-N

Gene Information:
human ... ADRB1(153)