Y0002069
Simvastatin for system suitability CRS
European Pharmacopoeia (EP) Reference Standard
Manufacturer: Sigma Aldrich
CAS Number: 79902-63-9
Synonym(S): Simvastatin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | Y0002069-5-MG | In Stock | ₹ 15,295.73 |
Y0002069 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 15,295.73
GST (18%): ₹ 2,753.231
Total Price: ₹ 18,048.961
grade
pharmaceutical primary standard
API family
simvastatin
manufacturer/tradename
EDQM
mp
127-132 °C (lit.)
application(s)
pharmaceutical
format
neat
storage temp.
2-8°C
SMILES string
[H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]3C[C@@H](O)CC(=O)O3)OC(=O)C(C)(C)CC
InChI
1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
InChI key
RYMZZMVNJRMUDD-HGQWONQESA-N
Other Options
Description
- General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
- Application: Simvastatin for system suitability CRS EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
- Biochem/physiol Actions: Simvastatin is a specific inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. It is used in the treatment of hypercholesterolemia, as it reduces levels of low-density lipoproteins and triglycerides, and raises high-density lipoprotein levels. Simvastatin is a lactone that is readily hydrolyzed in vivo to the corresponding β-hydroxyacid, and can be activated prior to use with NaOH in EtOH treatment. It is a synthetic analog of lovastatin (Cat. No. M2147).
- Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
- Other Notes: Sales restrictions may apply.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Repr. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
grade: pharmaceutical primary standard
API family: simvastatin
manufacturer/tradename: EDQM
mp: 127-132 °C (lit.)
application(s): pharmaceutical
format: neat
storage temp.: 2-8°C
SMILES string: [H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]3C[C@@H](O)CC(=O)O3)OC(=O)C(C)(C)CC
InChI: 1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
InChI key: RYMZZMVNJRMUDD-HGQWONQESA-N
grade:
pharmaceutical primary standard
API family:
simvastatin
manufacturer/tradename:
EDQM
mp:
127-132 °C (lit.)
application(s):
pharmaceutical
format:
neat
storage temp.:
2-8°C
SMILES string:
[H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]3C[C@@H](O)CC(=O)O3)OC(=O)C(C)(C)CC
InChI:
1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
InChI key:
RYMZZMVNJRMUDD-HGQWONQESA-N
grade: pharmaceutical primary standard
API family: folic acid
manufacturer/tradename: EDQM
mp: __
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: −20°C
SMILES string: __
InChI: __
InChI key: __
grade:
pharmaceutical primary standard
API family:
folic acid
manufacturer/tradename:
EDQM
mp:
__
application(s):
pharmaceutical (small molecule)
format:
neat
storage temp.:
−20°C
SMILES string:
__
InChI:
__
InChI key:
__
grade: __
API family: __
manufacturer/tradename: EDQM
mp: __
application(s): __
format: __
storage temp.: 2-8°C
SMILES string: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1
InChI: 1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+
InChI key: OENHQHLEOONYIE-JLTXGRSLSA-N
grade:
__
API family:
__
manufacturer/tradename:
EDQM
mp:
__
application(s):
__
format:
__
storage temp.:
2-8°C
SMILES string:
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1
InChI:
1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+
InChI key:
OENHQHLEOONYIE-JLTXGRSLSA-N
grade: pharmaceutical primary standard
API family: omeprazole
manufacturer/tradename: EDQM
mp: __
application(s): __
format: neat
storage temp.: 2-8°C
SMILES string: __
InChI: 1S/C17H20N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8,17,19H,9H2,1-4H3;/q-1;+1/t17?,24-;/m0./s1
InChI key: ALGZIPAMEDTMAM-DPGOWHRRSA-N
grade:
pharmaceutical primary standard
API family:
omeprazole
manufacturer/tradename:
EDQM
mp:
__
application(s):
__
format:
neat
storage temp.:
2-8°C
SMILES string:
__
InChI:
1S/C17H20N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8,17,19H,9H2,1-4H3;/q-1;+1/t17?,24-;/m0./s1
InChI key:
ALGZIPAMEDTMAM-DPGOWHRRSA-N