Y0002361

Saxagliptin

for system suitability CRS, European Pharmacopoeia (EP) Reference Standard

Manufacturer: Supelco

CAS Number: 945667-22-1

Synonym(S): Saxagliptin hydrate, (S)-3-Hydroxyadamantylglycine-L-cis-4,5-methanoprolinenitrile hydrate, BMS 477118, BMS 477118-11, BMS-477118, BMS-477118-11, BMS477118, BMS477118-11

Select a Size

Pack Size SKU Availability Price
1.082 MG Y0002361-1.082-MG In Stock ₹ 12,773.50

Y0002361 - 1.082 MG

₹ 12,773.50

In Stock

Quantity

1

Base Price: ₹ 12,773.50

GST (18%): ₹ 2,299.23

Total Price: ₹ 15,072.73

grade

pharmaceutical primary standard

manufacturer/tradename

EDQM

application(s)

pharmaceutical

storage temp.

2-8°C

SMILES string

OC12CC([C@@H](C(N3[C@@H](C[C@]4([C@@]3(C4)[H])[H])C#N)=O)N)(CC(C5)C2)CC5C1.O

InChI

1S/C18H25N3O2.H2O/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17;/h10-15,23H,1-7,9,20H2;1H2/t10?,11?,12-,13+,14+,15-,17?,18?;/m1./s1

InChI key

AFNTWHMDBNQQPX-NHKADLRUSA-N

Other Options

Image Product Name Manufacturer Price Range
Y0002369
Saxagliptin monohydrate
Supelco ₹ 12,773.50
AR003AYU
(1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrate(1:1)
Aaron Chemicals LLC ₹ 1,026.72 - ₹ 16,684.20
CS-3250
Saxagliptin (hydrate)
ChemScene ₹ 4,278.00 - ₹ 22,245.60
AB53082
945667-22-1 | Saxagliptin hydrate
A2B Chem ₹ 427.80 - ₹ 2,139.00

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Description

  • General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
  • Application: Saxagliptin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
  • Biochem/physiol Actions: Saxagliptin (BMS-477118) is an orally active, highly potent and long-acting dipeptidyl peptidase IV inhibitor (human DPP-IV Ki = 0.9 nM; plasma DDP-IV inhibition = 87% 0.5-4h post 4 μmol/kg po. in normal rats) with therapeutic efficacy against type 2 diabetes in vivo (plasma glucose clearance = 28/43/61% post 0.3/1.0/3.0 μmol/kg po. in Zucker fa/fa rats).
  • Packaging: Unit quantity: 1.082mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
  • Other Notes: Sales restrictions may apply.

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H317,H334,H361fd,H372

Precautionary Statements

P202 - P260 - P264 - P280 - P302 + P352 - P308 + P313

Hazard Classifications

Repr. 2 - Resp. Sens. 1 - Skin Sens. 1 - STOT RE 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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OC12CC([C@@H](C(N3[C@@H](C[C@]4([C@@]3(C4)[H])[H])C#N)=O)N)(CC(C5)C2)CC5C1.O

InChI:
1S/C18H25N3O2.H2O/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17;/h10-15,23H,1-7,9,20H2;1H2/t10?,11?,12-,13+,14+,15-,17?,18?;/m1./s1

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AFNTWHMDBNQQPX-NHKADLRUSA-N

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[Na+].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP(O)([O-])=O)c2cc1C

InChI:
1S/C17H21N4O9P.Na/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29;/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29);/q;+1/p-1/t11-,12+,14-;/m0./s1

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OHSHFZJLPYLRIP-BMZHGHOISA-M

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__

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__