7163831

Stoelting™ Ugo Basile Paw Pressure Analgesia Meter

Stoelting™ Ugo Basile Paw Pressure Analgesia Meter is for the rapid precise screening of analgesic drugs

Manufacturer: Fischer Scientific

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For Use With (Application)

Neuroscience

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Description

  • Designed for the Randall-Selitto test, which requires the application of increasing pressure on the paw between a flat surface and a blunt pointer
  • Usually used with animals with one paw inflamed by an injection and one normal paw to evaluate drugs for analgesic action.Principle of OperationThe device exerts a steadily increasing force (16 grams per second) on the rat paw until the animal makes a stereotyped flinch response
  • The researcher releases a foot pedal to stop the force indicator
  • The electronics measures the time interval between the start of the slide motion and the moment the slide is stopped by the operator and converts time into force.The force is measured on the scale calibrated in 10-gram steps, by a pointer riveted to the slide
  • The scale can be multiplied by 2 or 3, by placing one or two disc weights on the slide.

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