Mouse IgM Isotype Control (11E10), eFluor™ 450, eBioscience™, Invitrogen™

Description

• Description: The mouse IgM is useful as an isotype control immunoglobulin
• The immunoglobulin was generated by immunization with lipopolysaccharide (LPS)
• The immunoglobulin is reactive with LPS
• Applications Reported: eFluorTM 450 Mouse IgM Isotype Control has been reported for use in flow cytometric analysis
• Applications Tested: eFluorTM 450 Mouse IgM Isotype Control has been tested by flow cytometric analysis of normal human peripheral blood cells
• Use at the same concentration as the experimental antibody
• eFluor® 450 is an alternative to Pacific Blue®
• eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm)
• Please make sure that your instrument is capable of detecting this fluorochome
• Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser
• Filtration: 0.2 μm post-manufacturing filtered
• Mouse IgM is an immunoglobulin M antibody that is produced by B cells in response to an antigen
• It is the first antibody produced during an immune response and is the largest immunoglobulin in the serum
• Mouse IgM is composed of five heavy chains and five light chains, and it is involved in complement activation and agglutination of antigens
• It plays a crucial role in the innate immune response and is important for neutralizing pathogens before the adaptive immune response is fully activated
• Mouse IgM is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry.