Adenovirus Type 1 Monoclonal Antibody (1M13), Invitrogen™

Description

• MA1-7599 detects Adenovirus from virus samples
• MA1-7599 has been successfully used in ELISA, Western blot and Immunofluorescence procedures
• The MA1-7599 immunogen is a purified Ad1 virus
• Adenoviruses are DNA viruses generally widespread in nature that are frequently the cause of acute upper respiratory tract infections (i.e
• common colds)
• 49 human adenovirus serotypes have been discovered and divided into six subgroups, A to E, based on observation
• They are an important cause of respiratory illness, conjunctivitis, gastroenteritis, and have more recently been recognized as a potential cause of sexually transmitted diseases
• Several types have oncogenic potential though most cause self-limiting febrile illnesses characterized by inflammation of conjunctivae and the respiratory tract
• The virus can be isolated from the majority of tonsils/adenoids surgically removed, indicating latent infections
• It is not known how long the virus can persist in the body, or whether it is capable of reactivation after long periods
• In patients experiencing immunosuppression (e.g
• AIDS) it can be reactivated, causing disease
• Adenovirus vectors, particularly those based on Ad5, have shown great promise for the development of gene therapy protocols and have been used for clinical purpose.