01-670-389

CD45 Monoclonal Antibody (ICO-166), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-670-389-Each-of-1 In Stock ₹ 37,560.84

01-670-389 - Each of 1

₹ 37,560.84

In Stock

Quantity

1

Base Price: ₹ 37,560.84

GST (18%): ₹ 6,760.951

Total Price: ₹ 44,321.791

Antigen

CD45

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative; pH 7.2

Gene Accession No.

P08575

Gene Symbols

PTPRC

Immunogen

B-cells, T-cells, NK-cells.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

ELISA, Immunoprecipitation

Clone

ICO-166

Conjugate

Unconjugated

Gene

PTPRC

Gene Alias

B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5788

Content And Storage

4°C short term, -80°C long term

Form

Liquid

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Description

  • MA1-7655 detects CD45 from human samples
  • MA1-7655 has been successfully used in Immunoprecipitation and ELISA procedures
  • The MA1-7655 immunogen is B-cells, T-cells, NK-cells
  • CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
  • CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
  • CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling
  • CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.

Compare Similar Items

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Img

Thermo Scientific

01-670-389

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Antigen:
CD45

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Immunogen:
B-cells, T-cells, NK-cells.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA, Immunoprecipitation

Clone:
ICO-166

Conjugate:
Unconjugated

Gene:
PTPRC

Gene Alias:
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
4°C short term, -80°C long term

Form:
Liquid

Img

Thermo Scientific

01-670-390

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Antigen:
ICAM-3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% gelatin, 0.5% saccharose and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P32942

Gene Symbols:
ICAM3

Immunogen:
Leukocytes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
ICO-60

Conjugate:
Unconjugated

Gene:
ICAM3

Gene Alias:
CD50; CDw50; ICAM3; ICAM-3; ICAM-R; Intercellular adhesion molecule 3; intercellular adhesion molecule-3

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3385

Content And Storage:
4°C short term, -80°C long term

Form:
Liquid

Img

Thermo Scientific

01-670-391

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Antigen:
Transferrin Receptor

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% gelatin, 0.5% saccharose and 0.1% sodium azide; pH 7.4

Gene Accession No.:
P02786

Gene Symbols:
TFRC

Immunogen:
Transferrin receptor on activated T-B-cells.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
ICO-92

Conjugate:
Unconjugated

Gene:
TFRC

Gene Alias:
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7037

Content And Storage:
4°C short term, -80°C long term

Form:
Liquid

Img

Thermo Scientific

01-670-393

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Antigen:
HLA-DR

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.01% sodium azide; pH 7.2

Gene Accession No.:
P01903, P01911, P04233, P13762, P79483, Q30154

Gene Symbols:
CD74, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5

Immunogen:
HLA-DR.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG3

Applications:
Flow Cytometry, Immunohistochemistry

Clone:
ICO-1

Conjugate:
Unconjugated

Gene:
HLA-DRB4

Gene Alias:
AI323765; BLA-DRB3; BOLA-DRA; BoLA-DR-alpha; BoLA-DRB; BOLA-DRB3; BoLA-DRB3 protein; BoLA-DRB3.2; Bota-DRB01; Bota-DRB02; Bota-DRB04; Bota-DRB07; Bota-DRB21; Bota-DRB22; bovine leukocyte antigen; Cd74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule; Cd74 molecule, major histocompatibility complex, class II invariant chain; class II-associated invariant chain peptide; CLIP; Clone P2-beta-3; DASS-397D15.1; DHLAG; dinucleotide microsatellite; DLA class II histocompatibility antigen, DR-1 beta chain; DLA DRBB1 beta chain; DLA-DR beta; DLA-DRB1; DLA-DRBB1; DR beta-5; DR beta-chain antigen binding domain; DR-16; DR2-beta-2; DR4; DR-4; DR7; DR9; DR-9; DRB; DRB1; DRB1 transplantation antigen; DRB3; DRB4; DRBB1; DR-beta chain; DR-beta chain MHC class II; DRw10; Dw2; DW2.2/DR2.2; E-alpha-f; FLJ51114; FLJ75017; FLJ76359; gamma chain of class II antigens; H-2 class II histocompatibility antigen gamma chain; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H-2Ea; H2-Ea; H2-Ea-ps; H2-IE-alpha; histocompatibility 2, class II antigen E alpha; histocompatibility 2, class II antigen E alpha, pseudogene; histocompatibility antigen HLA-DR alpha; histocompatibility complex, class II, DR beta 3; histocompatibility: class II antigens, gamma chain of; HLA class II histocompatibility antigen gamma chain; HLA class II histocompatibility antigen, DR alpha chain; HLA class II histocompatibility antigen, DR beta 3 chain; HLA class II histocompatibility antigen, DR beta 4 chain; HLA class II histocompatibility antigen, DR beta 5 chain; HLA class II histocompatibility antigen, DR-1 beta chain; HLA class II histocompatibility antigen, DR-5 beta chain; HLA class II histocompatibility antigen, DRB1-15 beta chain; HLA class II histocompatibility antigen, DRB1-16 beta chain; HLA class II histocompatibility antigen, DRB1-3 chain; HLA class II histocompatibility antigen, DRB1-7 beta chain; HLA class II histocompatibility antigen, DRB1-9 beta chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR1B; HLA-DR3B; HLA-DR4B; HLA-DRA; HLA-DRA1; HLA-DRB; HLA-DRB1; HLA-DRB2; HLA-DRB3; HLA-DRB4; HLA-DRB5; HLA-DR-gamma; human leucocyte antigen DRB1; human leucocyte antigen DRB3; human leucocyte antigen DRB4; human leucocyte antigen DRB5; ia antigen-associated invariant chain; Ia3; Ia-3; Ia-associated invariant chain; Ia-GAMMA; I-E alpha MHC class II; I-Ealpha; II; integral membrane glycoprotein; invariant gamma chain; invariant polypeptide of major histocompatibility complex, class II antigen-associated; INVG34; LA-DRB; leukocyte antigen; leukocyte antigen class II; leukocyte antigen DRB3; lymphocyte antigen DRB1; major histocompatibility complex class II DR-beta chain; major histocompatibility complex, class II, DR alpha; major histocompatibility complex, class II, DR alpha precursor; major histocompatibility complex, class II, DR beta 1; major histocompatibility complex, class II, DR beta 3; major histocompatibility complex, class II, DR beta 4; major histocompatibility complex, class II, DR beta 4 precursor; major histocompatibility complex, class II, DR beta 5; major histocompatibility complex, class II, DRB3; MHC cell surface glycoprotein; MHC class I antigen; MHC class II antigen; MHC class II antigen beta chain; MHC class II antigen BoLA-DRB3; MHC class II antigen DR beta 3 chain; MHC class II antigen DRA; MHC class II antigen DRB1*15; MHC class II antigen DRB1*16; MHC class II antigen DRB1*3; MHC class II antigen DRB1*9; MHC class II antigen DRB3; MHC class II antigen DRB4; MHC class II antigen DRB5; MHC class II antigen E alpha; MHC class II antigen HLA-DR-beta; MHC class II DLA DRB1 beta chain; MHC class II DLA-DRB; MHC class II DLA-DR-beta-1; MHC class II DR beta 1; MHC class II DR beta chain; MHC class II DR beta-chain; MHC class II DR-ALPHA

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3122, 3123, 3125, 3126, 3127, 972

Content And Storage:
4°C short term, -80°C long term

Form:
Liquid