01-670-996

p21 Monoclonal Antibody (DCS-60), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-670-996-Each-of-1 In Stock ₹ 50,352.06

01-670-996 - Each of 1

₹ 50,352.06

In Stock

Quantity

1

Base Price: ₹ 50,352.06

GST (18%): ₹ 9,063.371

Total Price: ₹ 59,415.431

Antigen

p21

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.08% sodium azide

Gene Accession No.

P38936

Gene Symbols

CDKN1A

Immunogen

Full length recombinant p21protien.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

DCS-60

Conjugate

Unconjugated

Gene

CDKN1A

Gene Alias

Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

1026

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Protein p21 is a tumor suppressor protein which is an inhibitor of Cyclin-dependent kinases (CDK) and is transcriptionally activated by p53
  • P21 is important in the response of cells to genotoxic stress and a major transcriptional target of p53 protein
  • The occurrence of p21 in the nucleus executes binding and inhibition activity of cyclin dependent kinases Cdk1 and Cdk2, and blocks the transition from G1 phase into S phase or from G2 phase into mitosis after DNA damage, which enables the repair of damaged DNA
  • In the cytoplasm, p21 protein has an anti-apoptotic effect
  • P21 is able to bind to and inhibit caspase 3, as well as the apoptotic kinases ASK1 and JNK
  • P21 exhibits a dual function in carcinogenesis, and acts as a tumor suppressor, prevents apoptosis, and acts as an oncogene.

Compare Similar Items

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Img

Thermo Scientific

01-670-996

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Antigen:
p21

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.08% sodium azide

Gene Accession No.:
P38936

Gene Symbols:
CDKN1A

Immunogen:
Full length recombinant p21protien.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
DCS-60

Conjugate:
Unconjugated

Gene:
CDKN1A

Gene Alias:
Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
1026

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

01-671-028

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Antigen:
MVP

Classification:
Monoclonal

Concentration:
0.25 mg/mL

Formulation:
antibody with 1% BSA and 0.1% sodium azide

Gene Accession No.:
Q14764

Gene Symbols:
MVP

Immunogen:
110 kDa LRP-protein (p110).

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
LMR5

Conjugate:
Unconjugated

Gene:
MVP

Gene Alias:
2310009M24Rik; LRP; Lung resistance-related protein; major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
9961

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

01-671-029

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Antigen:
MVP

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant with 0.7% BSA and 0.1% sodium azide

Gene Accession No.:
Q14764

Gene Symbols:
MVP

Immunogen:
Fusion protein containing internal epitope of LRP

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
MVP-37

Conjugate:
Unconjugated

Gene:
MVP

Gene Alias:
2310009M24Rik; LRP; Lung resistance-related protein; major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
9961

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-671-031

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Antigen:
Macrophages / Histiocytes

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 1% BSA and 0.1% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Human Uvomorulin.

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
3A5

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Histiocyte; Macrophage; Monocyte

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid