01-674-053

3-Nitrotyrosine Monoclonal Antibody (2A12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-674-053-Each-of-1 In Stock ₹ 48,555.30

01-674-053 - Each of 1

₹ 48,555.30

In Stock

Quantity

1

Base Price: ₹ 48,555.30

GST (18%): ₹ 8,739.954

Total Price: ₹ 57,295.254

Antigen

3-Nitrotyrosine

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 3mM sodium azide; pH 7.5

Host Species

Mouse

Purification Method

Ion-exchange chromatography

Regulatory Status

RUO

Target Species

Chemical

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

2A12

Conjugate

Unconjugated

Gene Alias

3-Nitro-tyrosine; C9H10N2O5

Immunogen

3-Nitrotyrosine-KLH.

Quantity

100 μg

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Target Molecule

Chemical

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Description

  • Protein tyrosine nitration results in a post-translational modification that is increasingly receiving attention as an important component of nitric oxidesignaling
  • While multiple nonenzymatic mechanisms are known to be capable of producing nitrated tyrosine residues, most tyrosine nitration events involve catalysis by metalloproteins such as myeloperoxidase, eosinophilperoxidase, myoglobin, the cytochrome P-450s, superoxide dismutase and prostacyclin synthase
  • Various studies have shown that protein tyrosinenitration is limited to specific proteins and that the process is selective
  • For example, exposure of human surfactant protein A (SP-A) to oxygen-nitrogen intermediates generated by activated alveolar macrophages resulted in specific nitration of SP-A at tyrosines 164 and 166, while addition of 1.2 mMCO 2 resulted in additional nitration at tyrosine 161
  • The presence of nitrotyrosine-containing proteins has shown high correlation to disease states such as atherosclerosis, Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis.

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Img

Thermo Scientific

01-674-053

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Antigen:
3-Nitrotyrosine

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 3mM sodium azide; pH 7.5

Host Species:
Mouse

Purification Method:
Ion-exchange chromatography

Regulatory Status:
RUO

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
2A12

Conjugate:
Unconjugated

Gene Alias:
3-Nitro-tyrosine; C9H10N2O5

Immunogen:
3-Nitrotyrosine-KLH.

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
Chemical

Img

Thermo Scientific

01-674-090

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Antigen:
CYP26A1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.08% sodium azide

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
F27 P6 A1

Conjugate:
Unconjugated

Gene Alias:
CP26; Cyp26; CYP26A1; Cytochrome P450 26A1; cytochrome P450 family 26 subfamily A member 1; cytochrome P450 retinoic acid-inactivating 1; cytochrome P450, 26, retinoic acid; cytochrome P450, 26, retinoic acid A1; cytochrome P450, family 26, subfamily A, polypeptide 1; cytochrome P450, subfamily XXVIA, polypeptide 1; cytochrome P450RAI; hP450RAI; P450, retinoic acid-inactivating, 1; P450RA; P450RAI; P450RAI1; RAH; Retinoic acid 4-hydroxylase; retinoic acid hydrolase; retinoic acid hydroxylase; retinoic acid-metabolizing cytochrome

Immunogen:
Synthetic peptide corresponding to human CYP450 26A1.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
__

Img

Thermo Scientific

01-674-092

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Antigen:
MMP1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.08% sodium azide

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
3B6

Conjugate:
Unconjugated

Gene Alias:
22 kDa interstitial collagenase; 27 kDa interstitial collagenase; CLG; CLGN; Collagenase; collagenase-like A; fibroblast collagenase; Interstitial collagenase; interstitial collagenase A; matrix metallo protease; matrix metallopeptidase 1; matrix metallopeptidase 1 (interstitial collagenase); matrix metallopeptidase 1a; matrix metallopeptidase 1a (interstitial collagenase); matrix metalloprotease 1; matrix metalloproteinase 1; matrix metalloproteinase 1a (interstitial collagenase); Matrix metalloproteinase1; Matrix metalloproteinase-1; Matrix metalloproteinase-1a; McolA; Mcol-A; MMP; MMP1; MMP-1; Mmp1a; MMP-1a; MMPs

Immunogen:
Synthetic peptide derived from the C-terminus of the human MMP1.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
__

Img

Thermo Scientific

01-674-094

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Antigen:
MMP3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.08% sodium azide

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
1B4

Conjugate:
Unconjugated

Gene Alias:
CHDS6; EC 3.4.24.17; EMS-2; matrix metallo protease; matrix metallopeptidase 3; matrix metallopeptidase 3 (stromelysin 1, progelatinase); matrix metalloproteinase 3; matrix metalloproteinase 3 (stromelysin 1, progelatinase); matrix metalloproteinase 3 precursor; matrix metalloproteinase-3; metalloproteinase 3 receptor; MMP; MMP10; MMP3; MMP-3; MMP-3 protein; MMPs; progelatinase; proteoglycanase; SL-1; SLN1; SLN-1; STMY; STMY1; Str1; STR-1; stromelysin; stromelysin 1; Stromelysin1; stromelysin-1; Transin1; Transin-1

Immunogen:
Synthetic peptide derived from the C-terminus of the human MMP3

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
__