01-674-587

ADAM17 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-674-587-Each-of-1 In Stock ₹ 44,705.10

01-674-587 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ADAM17

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ADAM17

Gene Alias

a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

6868

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

P78536

Gene Symbols

ADAM17

Immunogen

Synthetic peptide corresponding to the C terminus amino acids LQRQNRVDSKETEC.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with mouse and rat based on sequence homology
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000
  • ADAM17 (disintegrin and metalloproteinase domain-containing protein 17) cleaves the membrane bound precusor of TNF-alpha to its mature soluble form
  • ADAM 17 is responsbile for the proteolytical release of soluble JAM3 from endothelial cells surface and the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1, and the amyloid precursor protein
  • It acts as an activator of the Notch pathway by mediating cleavage of Notch and generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT)
  • Mutations in the gene can result in inflammatory skin and bowel disease, neonatal 1.

Compare Similar Items

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Thermo Scientific

01-674-587

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Antigen:
ADAM17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADAM17

Gene Alias:
a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
6868

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P78536

Gene Symbols:
ADAM17

Immunogen:
Synthetic peptide corresponding to the C terminus amino acids LQRQNRVDSKETEC.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-674-588

--


Antigen:
AKT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKT3

Gene Alias:
AI851531; AKT serine/threonine kinase 3; Akt3; AKT3 kinase; akt3a; D930002M15Rik; DKFZP434N0250; MPPH; MPPH2; Nmf350; PKB gamma; PKBG; PKB-GAMMA; PRKBG; Protein kinase Akt-3; protein kinase B gamma; protein kinase B, gamma; RAC-gamma; RAC-gamma serine/threonine protein kinase; RAC-gamma serine/threonine-protein kinase; RAC-PK-gamma; si:ch211-221n23.2; STK-2; thymoma viral proto-oncogene 3; v-akt murine thymoma viral oncogene 3; v-akt murine thymoma viral oncogene homolog 3; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); v-akt murine thymoma viral oncogene homolog 3a; v-akt murine thymoma viral oncogene-like 3

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
10000, 23797, 29414

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q63484, Q9WUA6, Q9Y243

Gene Symbols:
AKT3

Immunogen:
Internal sequence corresponding to amino acids CSPTSQIDNIGEEEM.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-674-590

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Antigen:
Annexin A2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ANXA2

Gene Alias:
33-kDa calcimedin; 33-kDa lymphocyte Ca<2+>- binding protein; 33kDa lymphocyte Ca<2+>- binding protein; 36-kDa calelectrin; annexin 2; annexin A2; annexin A2 isoform 2; annexin II; Annexin-2; ANX2; ANX2L4; ANXA2; AW215814; CAL1H; calpactin I heavy chain; calpactin I heavy chain (p36); calpactin I heavy polypeptide; calpactin-1 heavy chain; chromobindin 8; chromobindin-8; epididymis secretory protein Li 270; HEL-S-270; LIP2; lipocortin II; LPC2; LPC2D; p36; PAP-IV; Placental anticoagulant protein IV; protein I

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
12306, 302

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P07355, P07356

Gene Symbols:
ANXA2

Immunogen:
Synthetic peptide corresponding to the N-terminus residues S T V H E I L C K L S L E G D.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-674-592

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Antigen:
LDLRAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LDLRAP1

Gene Alias:
AA691260; Arh; Arh1; ARH2; Autosomal recessive hypercholesterolemia protein; autosomal recessive hypercholesterolemia protein homolog; DKFZp586D0624; FHCB1; FHCB2; LDL receptor adaptor protein; LDLRAP1; Low density lipoprotein receptor adapter protein 1; low density lipoprotein receptor adaptor protein 1; MGC34705; RGD1563417; RP11-70P17.2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
26119

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q5SW96

Gene Symbols:
LDLRAP1

Immunogen:
Synthetic peptide corresponding to the N terminus amino acids DALKSAGRALIRS.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG