01-674-896
HEF1 Monoclonal Antibody (2G9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-896-Each-of-1 | In Stock | ₹ 71,784.84 |
01-674-896 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 71,784.84
GST (18%): ₹ 12,921.271
Total Price: ₹ 84,706.111
Antigen
HEF1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
O35177, Q14511
Gene Symbols
NEDD9
Immunogen
Fusion protein, corresponding to amino acids 82-398 of Human HEF1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1 κ
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone
2G9
Conjugate
Unconjugated
Gene
NEDD9
Gene Alias
Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
18003, 291044, 4739
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody detects HEF1 in human, mouse, and rat samples
- This antibody does not recognize p130cas
- It has not been tested on Sin1
- This antibody mostly detects HEF1 localized at the focal adhesion sites
- HEF-1 is a multifunctional protein involved in integrin-based signaling that affects cell motility, growth, apoptosis and oncogenic transformation
- The Cas family of docking proteins have been the subject of intense research because of their role in cell motility, growth, apoptosis and oncogenic transformation
- These proteins are substrates of focal adhesion kinase (FAK) and the Src family of tyrosine kinases two active targets for drug development
- HEF1 protein production increases levels of mRNA transcripts that encode proteins associated with motility, cell transformation and invasiveness, including several metalloproteinases, MLCK, p160ROCK and ErbBi
- HEF1 overproduction also mediates apoptosis in epithelial-derived cell lines, including MCF7 and HeLa cells
- Recent clinical studies at another institution have found that overexpression of BCAR1 (p130Cas), a related protein, is associated with tamoxifen resistance
- This highlights the importance of studying the role of this family of proteins in cancer prognosis.
Compare Similar Items
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Antigen: HEF1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: O35177, Q14511
Gene Symbols: NEDD9
Immunogen: Fusion protein, corresponding to amino acids 82-398 of Human HEF1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone: 2G9
Conjugate: Unconjugated
Gene: NEDD9
Gene Alias: Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 18003, 291044, 4739
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
HEF1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
O35177, Q14511
Gene Symbols:
NEDD9
Immunogen:
Fusion protein, corresponding to amino acids 82-398 of Human HEF1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone:
2G9
Conjugate:
Unconjugated
Gene:
NEDD9
Gene Alias:
Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
18003, 291044, 4739
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Kallikrein 2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: P20151
Gene Symbols: KLK2
Immunogen: Line tumor cells expressing hK2 from P3 cells
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone: 6B7
Conjugate: Unconjugated
Gene: KLK2
Gene Alias: glandular kallikrein 2; glandular kallikrein-1; hGK-1; hK2; kallikrein 2, prostatic; kallikrein related peptidase 2; kallikrein-2; kallikrein-related peptidase 2; KLK2; KLK2A2; MGC12201; Tissue kallikrein 2; Tissue kallikrein-2
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 3817
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Kallikrein 2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
P20151
Gene Symbols:
KLK2
Immunogen:
Line tumor cells expressing hK2 from P3 cells
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone:
6B7
Conjugate:
Unconjugated
Gene:
KLK2
Gene Alias:
glandular kallikrein 2; glandular kallikrein-1; hGK-1; hK2; kallikrein 2, prostatic; kallikrein related peptidase 2; kallikrein-2; kallikrein-related peptidase 2; KLK2; KLK2A2; MGC12201; Tissue kallikrein 2; Tissue kallikrein-2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
3817
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Lamin A/C
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: tissue culture supernatant with 0.1% sodium azide
Gene Accession No.: P02545, P48678, P48679
Gene Symbols: LMNA
Immunogen: Recombinant bacterially expressed full length protein
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: ChIP Assay, Immunocytochemistry, Western Blot
Clone: Jol3
Conjugate: Unconjugated
Gene: LMNA
Gene Alias: 70 kDa lamin; cb948; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; lamin; lamin A; lamin A/C; lamin A/C L homeolog; lamin A/C-like 1; Lamin A+C mutant; Lamin AC; lamin a-c; lamin C; lamin C2; lamin-A; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; lmna; LMNA protein; lmna.L; lmna-A; LMNC; LMNL1; mutant 453W; Mutant lamin A/C; nuclear intermediate filament protein; nuclear lamin A; prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32; RP11-54H19.1; unnamed protein product; wu:fk66d12; XELAEV_18040808mg
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 16905, 4000, 60374
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Lamin A/C
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
tissue culture supernatant with 0.1% sodium azide
Gene Accession No.:
P02545, P48678, P48679
Gene Symbols:
LMNA
Immunogen:
Recombinant bacterially expressed full length protein
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
ChIP Assay, Immunocytochemistry, Western Blot
Clone:
Jol3
Conjugate:
Unconjugated
Gene:
LMNA
Gene Alias:
70 kDa lamin; cb948; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; lamin; lamin A; lamin A/C; lamin A/C L homeolog; lamin A/C-like 1; Lamin A+C mutant; Lamin AC; lamin a-c; lamin C; lamin C2; lamin-A; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; lmna; LMNA protein; lmna.L; lmna-A; LMNC; LMNL1; mutant 453W; Mutant lamin A/C; nuclear intermediate filament protein; nuclear lamin A; prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32; RP11-54H19.1; unnamed protein product; wu:fk66d12; XELAEV_18040808mg
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
16905, 4000, 60374
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: MAD1
Classification: Monoclonal
Concentration: 0.9 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: Q9Y6D9
Gene Symbols: MAD1L1
Immunogen: Recombinant full length Mad1 protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation
Clone: 9B10
Conjugate: Unconjugated
Gene: MAD1L1
Gene Alias: AI173502; AW550425; coiled-coil domain-containing protein MAD1; hMAD1; HsMAD1; Mad1; MAD1 mitotic arrest deficient 1-like 1; MAD1 mitotic arrest deficient like 1; MAD1 mitotic arrest deficient-like 1; MAD1 mitotic arrest deficient-like 1 (yeast); MAD1L1; MAD1-like protein 1; mitotic arrest deficient 1-like 1; mitotic arrest deficient 1-like protein 1; Mitotic arrest deficient protein 1; Mitotic checkpoint MAD1 protein homolog; mitotic spindle assembly checkpoint protein MAD1; mitotic-arrest deficient 1, yeast, homolog-like 1; MXD1; PIG9; Spindle assembly checkpoint component MAD1; Tax-binding protein 181; TP53I9; tumor protein p53 inducible protein 9; TXBP181; YGL086W
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 8379
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MAD1
Classification:
Monoclonal
Concentration:
0.9 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
Q9Y6D9
Gene Symbols:
MAD1L1
Immunogen:
Recombinant full length Mad1 protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation
Clone:
9B10
Conjugate:
Unconjugated
Gene:
MAD1L1
Gene Alias:
AI173502; AW550425; coiled-coil domain-containing protein MAD1; hMAD1; HsMAD1; Mad1; MAD1 mitotic arrest deficient 1-like 1; MAD1 mitotic arrest deficient like 1; MAD1 mitotic arrest deficient-like 1; MAD1 mitotic arrest deficient-like 1 (yeast); MAD1L1; MAD1-like protein 1; mitotic arrest deficient 1-like 1; mitotic arrest deficient 1-like protein 1; Mitotic arrest deficient protein 1; Mitotic checkpoint MAD1 protein homolog; mitotic spindle assembly checkpoint protein MAD1; mitotic-arrest deficient 1, yeast, homolog-like 1; MXD1; PIG9; Spindle assembly checkpoint component MAD1; Tax-binding protein 181; TP53I9; tumor protein p53 inducible protein 9; TXBP181; YGL086W
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
8379
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid