01-675-196
Nanog Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-675-196-Each-of-1 | In Stock | ₹ 47,015.22 |
01-675-196 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
Nanog
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NANOG
Gene Alias
2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
71950, 79923
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.
Q80Z64, Q9H9S0
Gene Symbols
NANOG
Immunogen
Synthetic peptide corresponding to residues 1-50 of human NANOG.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- NANOG (Nanog homeobox) is a divergent homeodomain protein that directs pluripotency and differentiation of undifferentiated embryonic stem cells
- NANOG mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells
- Human NANOG protein shares 52% overall amino acid identity with the mouse protein, and 85% identity in the homeodomain
- Human NANOG maps to gene locus 12p13.31, while the mouse NANOG maps to gene loci 6 F2
- Murine embryonic NANOG expression is detected in the inner cell mass of the blastocyst
- Research studies have shown that high levels of human NANOG expression in the undifferentiated N-Tera embryonal carcinoma cell line
- Further, NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal
- The role of NANOG in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases
- Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 (also known as Oct-4), another germline-specific transcription factor, and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts
- Experiments have demonstrated that iPS cells could be generated using expression plasmids expressing NANOG, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine
- When overexpressed, NANOG promotes cells to enter into S phase and proliferation
- Diseases associated with dysfunction in the NANOG protein include tetracarcinoma and germ cell/embryonal cancer.
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Antigen: Nanog
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NANOG
Gene Alias: 2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 71950, 79923
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.: Q80Z64, Q9H9S0
Gene Symbols: NANOG
Immunogen: Synthetic peptide corresponding to residues 1-50 of human NANOG.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Nanog
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NANOG
Gene Alias:
2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
71950, 79923
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.:
Q80Z64, Q9H9S0
Gene Symbols:
NANOG
Immunogen:
Synthetic peptide corresponding to residues 1-50 of human NANOG.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: MRE11
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mre11
Gene Alias: ATLD; AT-like disease; DNA recombination and repair protein; double-strand break repair protein MRE11; Double-strand break repair protein MRE11A; endo/exonuclease Mre11; HNGS1; Meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A; meiotic recombination 11 homolog A (S. cerevisiae); mmMRE11A; MRE11; MRE11 double strand break repair nuclease A; MRE11 homolog 1; MRE11 homolog A; MRE11 homolog A, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease A; MRE11 meiotic recombination 11 homolog A; MRE11 meiotic recombination 11 homolog A (S. cerevisiae); MRE11 meiotic recombination 11-like protein A; MRE11A; MRE11B; MRX complex nuclease subunit; NGS1; RAD58; XRS4; YM9959.06C; YMR224C
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4361
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P49959
Gene Symbols: Mre11
Immunogen: Synthetic peptide corresponding to a portion of human MRE11.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MRE11
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mre11
Gene Alias:
ATLD; AT-like disease; DNA recombination and repair protein; double-strand break repair protein MRE11; Double-strand break repair protein MRE11A; endo/exonuclease Mre11; HNGS1; Meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A; meiotic recombination 11 homolog A (S. cerevisiae); mmMRE11A; MRE11; MRE11 double strand break repair nuclease A; MRE11 homolog 1; MRE11 homolog A; MRE11 homolog A, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease A; MRE11 meiotic recombination 11 homolog A; MRE11 meiotic recombination 11 homolog A (S. cerevisiae); MRE11 meiotic recombination 11-like protein A; MRE11A; MRE11B; MRX complex nuclease subunit; NGS1; RAD58; XRS4; YM9959.06C; YMR224C
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4361
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P49959
Gene Symbols:
Mre11
Immunogen:
Synthetic peptide corresponding to a portion of human MRE11.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: LFG
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FAIM2
Gene Alias: 2900002L20Rik; FAIM2; Fas apoptotic inhibitory molecule 2; fas apoptotic inhibitory molecule 2; protein lifeguard 2; Kiaa0950; Lfg; LFG2; lifeguard; neural membrane protein 35; NGP35; NMP25; Nmp35; protein lifeguard; protein lifeguard 2; TMBIM2; transmembrane BAX inhibitor motif-containing protein 2
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 23017, 246274, 477613, 72393
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.0 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: O88407, Q8K097, Q9BWQ8
Gene Symbols: FAIM2
Immunogen: Synthetic peptide corresponding to residues 1-50 of human Lifeguard.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LFG
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FAIM2
Gene Alias:
2900002L20Rik; FAIM2; Fas apoptotic inhibitory molecule 2; fas apoptotic inhibitory molecule 2; protein lifeguard 2; Kiaa0950; Lfg; LFG2; lifeguard; neural membrane protein 35; NGP35; NMP25; Nmp35; protein lifeguard; protein lifeguard 2; TMBIM2; transmembrane BAX inhibitor motif-containing protein 2
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
23017, 246274, 477613, 72393
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
O88407, Q8K097, Q9BWQ8
Gene Symbols:
FAIM2
Immunogen:
Synthetic peptide corresponding to residues 1-50 of human Lifeguard.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CD97
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ADGRE5
Gene Alias: AA409984; Adgre5; adhesion G protein-coupled receptor E5; Cd97; CD97 antigen; CD97 antigen subunit alpha; CD97 antigen subunit beta; CD97 molecule; EGF-TM7 receptor; leukocyte antigen CD97; seven transmembrane helix receptor; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation; TM7LN1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26364, 976
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.2% gelatin and 0.05% sodium azide
Gene Accession No.: P48960, Q9Z0M6
Gene Symbols: ADGRE5, CD97
Immunogen: Synthetic peptide corresponding to residues 220-270 of human Leukocyte antigen CD97.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate
Product Type: Antibody
Isotype: IgG
Antigen:
CD97
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ADGRE5
Gene Alias:
AA409984; Adgre5; adhesion G protein-coupled receptor E5; Cd97; CD97 antigen; CD97 antigen subunit alpha; CD97 antigen subunit beta; CD97 molecule; EGF-TM7 receptor; leukocyte antigen CD97; seven transmembrane helix receptor; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation; TM7LN1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26364, 976
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.2% gelatin and 0.05% sodium azide
Gene Accession No.:
P48960, Q9Z0M6
Gene Symbols:
ADGRE5, CD97
Immunogen:
Synthetic peptide corresponding to residues 220-270 of human Leukocyte antigen CD97.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate
Product Type:
Antibody
Isotype:
IgG