01-676-088

Syk Monoclonal Antibody (SYK-01), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-676-088-Each-of-1 In Stock ₹ 51,250.44

01-676-088 - Each of 1

₹ 51,250.44

In Stock

Quantity

1

Base Price: ₹ 51,250.44

GST (18%): ₹ 9,225.079

Total Price: ₹ 60,475.519

Antigen

Syk

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

P43405, P48025, Q64725

Gene Symbols

Syk

Immunogen

Recombinant fragment (aa 5-360) of human Syk.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

SYK-01

Conjugate

Unconjugated

Gene

Syk

Gene Alias

DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

20963, 25155, 6850

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • Spleen tyrosine kinase (SYK), along with ZAP70, are cytoplasmic tyrosine kinases that are viewed as potential druge targets for allergic disorders and autoimmune diseases
  • SYK may also play a role in cancer
  • Syk translocates to the plasma membrane upon B cell antigen receptor (BCR) or the high-affinity IgE receptor (FcepsilonRI) triggering, and phosphorylates downstream adaptor proteins, thereby providing docking sites for initiation of subsequent signaling pathways, such as calcium mobilization, cytoskeleton remodeling, or transcription of specific genes
  • Syk binds to the receptor assemblies through interactions of its pair of SH2 domains with ITAM motives of the receptor, which have been phosphorylated by Src-family kinases
  • These kinases also help to activate Syk by phosphorylation of its activation loop.

Compare Similar Items

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Img

Thermo Scientific

01-676-088

--


Antigen:
Syk

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P43405, P48025, Q64725

Gene Symbols:
Syk

Immunogen:
Recombinant fragment (aa 5-360) of human Syk.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
SYK-01

Conjugate:
Unconjugated

Gene:
Syk

Gene Alias:
DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20963, 25155, 6850

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-676-090

--


Antigen:
Lyn

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P07948, P25911, Q07014

Gene Symbols:
LYN

Immunogen:
Bacterially expressed recombinant fragment of human Lyn. (aa 8-238)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
LYN-01

Conjugate:
Unconjugated

Gene:
LYN

Gene Alias:
AA407514; CD180; CD180 antigen; CD180 molecule; CH73-38P6.3; FLJ26625; Hck-2; JTK8; lck/Yes-related novel protein tyrosine kinase; LY64; Ly78; lymphocyte antigen 64; lymphocyte antigen-64, radioprotective, 105kDa; LYN; lyn protein non-receptor kinase; lyn protein tyrosine kinase; LYN proto-oncogene, Src family tyrosine kinase; p53Lyn; p56Lyn; Radioprotective 105 kDa protein; RP105; Tyrosine-protein kinase Lyn; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; v-yes-1 Yamaguchi sarcoma viral related oncogene protein-like protein; Yamaguchi sarcoma viral (v-yes-1) oncogene homolog; zgc:92124

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17096, 4067, 81515

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-676-096

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Antigen:
CD16

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 15mM sodium azide; pH 8

Gene Accession No.:
O75015, P08637

Gene Symbols:
FCGR3A, FCGR3B

Immunogen:
Human granulocytes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate, Porcine

Product Type:
Antibody

Isotype:
IgM

Applications:
Flow Cytometry

Clone:
MEM-168

Conjugate:
Unconjugated

Gene:
FCGR3A

Gene Alias:
4833442P21Rik; CD16; CD16-2; CD16A; CD16a antigen; CD16b; CD32; CD32 receptor 2; CDw32; cytolytic trigger molecule G7; Fc fragment of IgG intermediate affinity IV receptor; Fc fragment of IgG low affinity IIIa receptor; Fc fragment of IgG receptor IIIa; Fc fragment of IgG receptor IIIb; Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor III; Fc gamma receptor IIIa; Fc gamma receptor III-A; Fc gamma receptor IIIb; Fc gamma RIIIa; Fc gammaRIV; Fc receptor, IgG, low affinity III; Fc receptor, IgG, low affinity IV; Fc receptor-like 3; Fcg receptor III; FCG2; FCG3; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD 16); Fc-gamma receptor IIIb (CD16); Fc-gamma RII-b; Fc-gamma RII-c; fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; fc-gamma RIIIb; fc-gamma RIII-beta; Fc-gamma-RIIb; Fc-gamma-RIIc; FcgammaRIII; FcgammaRIII a.1; FcgammaRIII a.2; FcgammaRIII a.3; FcgammaRIIIA; FcgammaRIV; FCGR2; FCGR2A; FCGR2B; FCGR2C; FCGR3; Fcgr3a; FCGR3B; Fcgr4; FCGRIII; FcgRIV; FcR-10; FcRII-b; FcRII-c; FcRIII; FCRIIIA; FCRIIIb; Fcrl3; IGFR3; IgG Fc gamma receptor III; igG Fc receptor III; IgG Fc receptor III-1; igG Fc receptor III-2; IMD20; immunoglobulin G Fc receptor III; LOC100911825; Low affinity immunoglobulin gamma Fc region receptor III; low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; low affinity immunoglobulin gamma Fc region receptor III-like; Low affinity immunoglobulin gamma Fc region receptor IV; neutrophil-specific antigen NA; RP11-5K23.1; transmembrane receptor FcgammaRIII-X

Host Species:
Mouse

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2214, 2215, 397684, 406193

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-676-098

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Antigen:
AFP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P02771

Gene Symbols:
AFP

Immunogen:
Purified alpha Fetoprotein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Radioimmune Assays (RIA), Western Blot

Clone:
AFP-11

Conjugate:
Unconjugated

Gene:
AFP

Gene Alias:
a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
174

Content And Storage:
4° C, do not freeze

Form:
Liquid