01-676-241

CD22 Monoclonal Antibody (MEM-01), Biotin, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-676-241-Each-of-1 In Stock ₹ 41,967.18

01-676-241 - Each of 1

₹ 41,967.18

In Stock

Quantity

1

Base Price: ₹ 41,967.18

GST (18%): ₹ 7,554.092

Total Price: ₹ 49,521.272

Antigen

CD22

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

P20273

Gene Symbols

CD22

Immunogen

Burkitt's lymphoma cell line Raji.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunoprecipitation, Western Blot

Clone

MEM-01

Conjugate

Biotin

Gene

CD22

Gene Alias

A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

933

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa
  • CD22 is expressed in both the cytoplasm and cell membrane of B-lymphocytes
  • CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen
  • Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 preferentially binds to alpha2,6-linked sialic acid
  • The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface
  • Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling
  • CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 is also positive in diffuse large B-cell lymphoma and nodular lymphocyte predominance Hodgkin’s lymphoma, but negative in classical Hodgkin’s lymphoma.

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-676-241

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Antigen:
CD22

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P20273

Gene Symbols:
CD22

Immunogen:
Burkitt's lymphoma cell line Raji.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunoprecipitation, Western Blot

Clone:
MEM-01

Conjugate:
Biotin

Gene:
CD22

Gene Alias:
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
933

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-676-242

--


Antigen:
ICAM-3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P32942

Gene Symbols:
ICAM3

Immunogen:
Human granulocytes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunoprecipitation

Clone:
MEM-171

Conjugate:
Biotin

Gene:
ICAM3

Gene Alias:
CD50; CDw50; ICAM3; ICAM-3; ICAM-R; Intercellular adhesion molecule 3; intercellular adhesion molecule-3

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3385

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-676-244

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Antigen:
CD31

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P16284

Gene Symbols:
Pecam1

Immunogen:
Leukocytes from a patient suffering from a LGL type leukaemia.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
MEM-05

Conjugate:
Biotin

Gene:
Pecam1

Gene Alias:
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5175

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-676-245

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Antigen:
CD147 (soluble)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P35613

Gene Symbols:
BSG

Immunogen:
Protein A-CR purified soluble recombinant form of CD147, CD147Rg.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
MEM-M6/1

Conjugate:
Biotin

Gene:
BSG

Gene Alias:
5A11; 5A11 antigen; 5A11/Basigin; 5A11/Basigin-2; 5F7; AI115436; AI325119; Basic immunoglobulin superfamily; basigin; basigin (Ok blood group); Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); basignin; Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); blood-brain barrier HT7 antigen; BSG; CD147; CD147 antigen; CE9; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; glycoprotein CE9; gp 42; gp42/basigin/OX-47/HT7; HT7; HT-7; HT7 antigen; immunoglobulin gene superfamily member; leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK; OK blood group antigen; OX-47 antigen; Ox47R; RPE7; TCSF; tumor cell-derived collagenase stimulatory factor; Unknown (protein for MGC:128392); unnamed protein product; UNQ6505/PRO21383

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
682

Content And Storage:
4° C, do not freeze

Form:
Liquid