01-676-452

PGRP-S Monoclonal Antibody (188C424), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-676-452-Each-of-1 In Stock ₹ 48,015.50

01-676-452 - Each of 1

₹ 48,015.50

In Stock

Quantity

1

Base Price: ₹ 48,015.50

GST (18%): ₹ 8,642.79

Total Price: ₹ 56,658.29

Antigen

PGRP-S

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O75594, O88593

Gene Symbols

PGLYRP1

Immunogen

Synthetic peptide, KLH-conjugated, corresponding to residues 165-180 of human PGRP-S.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG3 κ

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone

188C424

Conjugate

Unconjugated

Gene

PGLYRP1

Gene Alias

Cytokine tag7; MGC126894; MGC126896; peptidoglycan recognition protein 1; Peptidoglycan recognition protein short; Pglyrp; Pglyrp1; PGRP; PGRPS; PGRP-S; SBBI68; Tag7; Tasg7; TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein); TNFSF3L; UNQ639/PRO1269

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

21946, 8993

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Suggested positive control: mouse spleen lysate or protein
  • The primary immune recognition is based on structures common among invading pathogens
  • Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever
  • Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria
  • Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria (1,2) and, thus, it is an excellent target for recognition by the eukaryotic innate immune system
  • The PGRPs (PGRP-L, PGRP-S, PGRP-Ia, and PGRP-Ib) define a new family of human pattern recognition molecules (3)
  • PGRP-L is primarily expressed in the liver
  • Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood (4)
  • PGRP-S is present in neutrophils and inhibits growth of Gram-positive bacteria and, therefore, may function as a neutrophil antibacterial protein (5)
  • However, PGRP-S may have another, as yet unidentified function because in humans it is expressed in the bone marrow 50-100 times higher than in neutrophils.

Compare Similar Items

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Img

Thermo Scientific

01-676-452

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Antigen:
PGRP-S

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O75594, O88593

Gene Symbols:
PGLYRP1

Immunogen:
Synthetic peptide, KLH-conjugated, corresponding to residues 165-180 of human PGRP-S.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG3 κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
188C424

Conjugate:
Unconjugated

Gene:
PGLYRP1

Gene Alias:
Cytokine tag7; MGC126894; MGC126896; peptidoglycan recognition protein 1; Peptidoglycan recognition protein short; Pglyrp; Pglyrp1; PGRP; PGRPS; PGRP-S; SBBI68; Tag7; Tasg7; TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein); TNFSF3L; UNQ639/PRO1269

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21946, 8993

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-454

--


Antigen:
RANK

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O35305, Q9Y6Q6

Gene Symbols:
TNFRSF11A

Immunogen:
Recombinant protein corresponding to the extracellular domain (aa 33-208) of human RANK.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 λ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
64C1385.1

Conjugate:
Unconjugated

Gene:
TNFRSF11A

Gene Alias:
CD265; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; Ly109; mRANK; ODFR; OFE; OPTB7; Osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; Rank; receptor activator of NF-kappaB; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; RGD1563614; TNF receptor superfamily member 11a; Tnfrsf11a; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21934, 8792

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-455

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Antigen:
DR4

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O00220

Gene Symbols:
TNFRSF10A

Immunogen:
Synthetic peptide corresponding to residues 2-21 of mature human DR4.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Western Blot

Clone:
32A242

Conjugate:
Unconjugated

Gene:
TNFRSF10A

Gene Alias:
APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; MGC9365; sCD261; soluble CD261; soluble TRAIL; sTRAIL; TNF receptor superfamily member 10a; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TRAIL R1; TRAIL receptor 1; TRAILR1; TRAIL-R1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
8797

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-457

--


Antigen:
TEM8

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q9H6X2

Gene Symbols:
ANTXR1

Immunogen:
Synthetic peptide corresponding to residues 481-497 of human TEM8.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
200C1339 (SB20)

Conjugate:
Unconjugated

Gene:
ANTXR1

Gene Alias:
2310008J16Rik; 2810405N18Rik; anthrax toxin receptor; anthrax toxin receptor 1; Antrx1; ANTXR1; ATR; FLJ10601; FLJ11298; FLJ21776; GAPO; TEM8; Tem-8; tumor endothelial marker 8

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
84168

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid