01-676-479
pro-Caspase 3 Monoclonal Antibody (31A893), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-479-Each-of-1 | In Stock | ₹ 51,250.44 |
01-676-479 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,250.44
GST (18%): ₹ 9,225.079
Total Price: ₹ 60,475.519
Antigen
pro-Caspase 3
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P42574
Gene Symbols
CASP3
Immunogen
Recombinant full-length human Caspase-3.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
31A893
Conjugate
Unconjugated
Gene
CASP3
Gene Alias
A830040C14Rik; AC-3; Apopain; Casp3; CASP-3; caspase 3; caspase 3, apoptosis related cysteine protease; caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; CC3; Cpp32; CPP-32; CPP32B; cysteine protease CPP32; LICE; mLdy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
836
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Description
- Suggested positive control: HL-60 or staurosporine treated apoptotic HeLa
- Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis
- The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits
- The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions
- All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a2b2 tetramer to form the active enzyme
- Gene for Caspase-3 also known as Yama, CPP32, and apopain codes for a 32-kDa protein
- Caspase-3 cleaves the death substrate poly(ADP-ribose) polymerase (PARP) to a specific 85 kDa form observed during apoptosis and is inhibitable by the CrmA protein
- Other Caspase-3 substrates include DNA-PK, actin, GAS2, and procaspase-6, etc
- Caspase-3 is activated by cleavage events at Asp-28/Ser-29 (between N-terminal pro-domain) and Asp-175/Ser-176 (between large and small subunits) to generate a large subunit of 17-kDa and a small subunit of 12-kDa.
Compare Similar Items
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Antigen: pro-Caspase 3
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P42574
Gene Symbols: CASP3
Immunogen: Recombinant full-length human Caspase-3.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 31A893
Conjugate: Unconjugated
Gene: CASP3
Gene Alias: A830040C14Rik; AC-3; Apopain; Casp3; CASP-3; caspase 3; caspase 3, apoptosis related cysteine protease; caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; CC3; Cpp32; CPP-32; CPP32B; cysteine protease CPP32; LICE; mLdy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 836
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
pro-Caspase 3
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P42574
Gene Symbols:
CASP3
Immunogen:
Recombinant full-length human Caspase-3.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
31A893
Conjugate:
Unconjugated
Gene:
CASP3
Gene Alias:
A830040C14Rik; AC-3; Apopain; Casp3; CASP-3; caspase 3; caspase 3, apoptosis related cysteine protease; caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; CC3; Cpp32; CPP-32; CPP32B; cysteine protease CPP32; LICE; mLdy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
836
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: SARS Coronavirus Spike Protein
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Synthetic peptide corresponding to residues 1124-1140 of human SARS-Spike protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: 17F706R
Conjugate: Unconjugated
Gene: __
Gene Alias: Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Host Species: Mouse
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SARS Coronavirus Spike Protein
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Synthetic peptide corresponding to residues 1124-1140 of human SARS-Spike protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
17F706R
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Host Species:
Mouse
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Factor VIII
Classification: Monoclonal
Concentration: 8.1 mg/mL
Formulation: 50% water with 50% glycerol and no preservative
Gene Accession No.: Q06194
Gene Symbols: F8
Immunogen: Mouse Factor VIII.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: __
Applications: ELISA, Western Blot
Clone: 9035
Conjugate: Unconjugated
Gene: F8
Gene Alias: AHF; Antihemophilic factor; CF8; Cf-8; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; factor VIII precursor; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7
Host Species: Rat
Purification Method: Ammonium sulfate precipitation, Ion-exchange chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14069
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Factor VIII
Classification:
Monoclonal
Concentration:
8.1 mg/mL
Formulation:
50% water with 50% glycerol and no preservative
Gene Accession No.:
Q06194
Gene Symbols:
F8
Immunogen:
Mouse Factor VIII.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
__
Applications:
ELISA, Western Blot
Clone:
9035
Conjugate:
Unconjugated
Gene:
F8
Gene Alias:
AHF; Antihemophilic factor; CF8; Cf-8; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; factor VIII precursor; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7
Host Species:
Rat
Purification Method:
Ammonium sulfate precipitation, Ion-exchange chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14069
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: LBP
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.1% BSA and no preservative
Gene Accession No.: Q61805
Gene Symbols: LBP
Immunogen: Murine natural and recombinant LBP.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a
Applications: ELISA, Flow Cytometry
Clone: M330-19
Conjugate: Unconjugated
Gene: LBP
Gene Alias: acute phase protein; binds bacterial LPS; BPI fold containing family D, member 2; Bpifd2; hypothetical protein LOC512242; LBP; lipopolysaccharide binding protein; lipopolysaccharide-binding protein; lipopolysaccharide-binding protein LPSBP; LPS-binding protein; LPSBP; Ly88
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 16803
Content And Storage: 4° C
Form: Liquid
Antigen:
LBP
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.1% BSA and no preservative
Gene Accession No.:
Q61805
Gene Symbols:
LBP
Immunogen:
Murine natural and recombinant LBP.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a
Applications:
ELISA, Flow Cytometry
Clone:
M330-19
Conjugate:
Unconjugated
Gene:
LBP
Gene Alias:
acute phase protein; binds bacterial LPS; BPI fold containing family D, member 2; Bpifd2; hypothetical protein LOC512242; LBP; lipopolysaccharide binding protein; lipopolysaccharide-binding protein; lipopolysaccharide-binding protein LPSBP; LPS-binding protein; LPSBP; Ly88
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
16803
Content And Storage:
4° C
Form:
Liquid