01-676-528

Complement C3b Monoclonal Antibody (755), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-676-528-Each-of-1 In Stock ₹ 53,646.12

01-676-528 - Each of 1

₹ 53,646.12

In Stock

Quantity

1

Base Price: ₹ 53,646.12

GST (18%): ₹ 9,656.302

Total Price: ₹ 63,302.422

Antigen

Complement C3b

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.

P01024

Gene Symbols

C3

Immunogen

Native C3

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Western Blot

Clone

755

Conjugate

Unconjugated

Gene

C3

Gene Alias

Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; Complement C3; Complement C3 alpha chain; Complement C3 beta chain; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3a; complement component C3b; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; iC3b; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

718

Content And Storage

4° C

Form

Liquid

Description

  • MA1-40155 detects C3/C3b from human samples
  • MA1-40155 has been successfully used in ELISA and Western blot applications
  • In western blot, the band size is ∽190 kDa under non-reducing and ∽100 kDa under reducing conditions
  • The MA1-40155 immunogen is native C3
  • Positive control: Human serum; Negative control: C3 deficient serum Inactive complement component 3b (iC3b) is a 42kDa neoantigen present in blood serum
  • Cleavage of C3b into iC3b by the protease factor I, in the presence of cofactors, changes the structure and resulting binding properties, preventing binding by complement factor B and properdin
  • This prevents further progression of the complement pathway, providing another mechanism by which the complement pathway may be regulated
  • iC3b is thought to play a role in inducing tolerance, binding complement receptor type 3 on antigen presenting cells and stimulating them to produce transforming growth factor beta2 and interleukin-10
  • It is thought to stimulate B-cells via the CD21 receptor providing a link between the innate and adaptive immune responses
  • Additionally iC3b acts as an opsonin which is recognised by complement receptor 3 expressed on leukocytes or complement receptor of the immunoglobulin superfamily (CRIg) on Kupffer cells, stimulating phagocytosis of the tagged cells
  • iC3b levels are often elevated in diseases such as Systemic Lupus Erythematosis and Rheumatoid arthritis.

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Img

Thermo Scientific

01-676-528

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Antigen:
Complement C3b

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P01024

Gene Symbols:
C3

Immunogen:
Native C3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
755

Conjugate:
Unconjugated

Gene:
C3

Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; Complement C3; Complement C3 alpha chain; Complement C3 beta chain; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3a; complement component C3b; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; iC3b; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
718

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

01-676-529

--


Antigen:
Complement C3a

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P01024

Gene Symbols:
C3

Immunogen:
C3a antigen.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
474

Conjugate:
Unconjugated

Gene:
C3

Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; C3r1; Complement C3; complement C3 alpha chain; Complement C3 beta chain; complement C3 protein (GPC3) precursor; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3 alpha-chain; complement component C3a; complement component C3b; CPAMD1; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; Plp; prepro-C3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
718

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

01-676-530

--


Antigen:
Complement C3a

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P01024

Gene Symbols:
C3

Immunogen:
Human C3a des-Arg

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
2991

Conjugate:
Unconjugated

Gene:
C3

Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; C3r1; Complement C3; complement C3 alpha chain; Complement C3 beta chain; complement C3 protein (GPC3) precursor; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3 alpha-chain; complement component C3a; complement component C3b; CPAMD1; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; Plp; prepro-C3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
718

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

01-676-531

--


Antigen:
Complement C3a

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P01024

Gene Symbols:
C3

Immunogen:
C-terminus of C3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
2898

Conjugate:
Unconjugated

Gene:
C3

Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; C3r1; Complement C3; complement C3 alpha chain; Complement C3 beta chain; complement C3 protein (GPC3) precursor; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3 alpha-chain; complement component C3a; complement component C3b; CPAMD1; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; Plp; prepro-C3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
718

Content And Storage:
4° C

Form:
Liquid