01-676-570
Endostatin Monoclonal Antibody (1837-46), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-570-Each-of-1 | In Stock | ₹ 71,784.84 |
01-676-570 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 71,784.84
GST (18%): ₹ 12,921.271
Total Price: ₹ 84,706.111
Antigen
Endostatin
Classification
Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.
P39060
Gene Symbols
COL18A1
Immunogen
Recombinant human Endostatin
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone
1837-46
Conjugate
Unconjugated
Gene
COL18A1
Gene Alias
antiangiogenic agent; Col18a1; Collagen alpha-1(XVIII) chain; collagen type XVIII alpha 1 chain; collagen, type XVIII, alpha 1; endostatin; FLJ27325; FLJ34914; KNO; KNO1; KS; MGC74745; multi-functional protein MFP; NC1; Non-collagenous domain 1; procollagen, type XVIII, alpha 1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
80781
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA1-40230 detects Endostatin from human samples
- MA1-40230 has been successfully used in ELISA, flow cytometry, immunohistochemistry (frozen), immunohistochemistry (paraffin), and Western blot applications
- For staining of paraffin sections antigen retrieval (microwave irradiation <2x7 minutes> in citrate buffer) is advised
- The MA1-40230 immunogen is human endostatin
- Endostatin is able to avoke non-uniform response for proliferation, cell mount and migration of entothelial cells, which different endostatin binding characteristic, leads to the assumption that endostatin effect is strongly dependent from endothelial cell type
- Furthermore endostatin inhibits angiogenesis and tumor growth in vivo by inducing apoptosis in endothelial cells
- The local delivery of endostatin seems to specifically affect tumor-associated microvessels by reduction of the vessel density, diameter and functionality
- Tumor cell migration and invasion was greatly reduced in the endostatin treated animals
- Endostatin is non-toxic and does not induce aquired drug resistance and has therefor become a potent new therapy strategy in solid neoplasias
- This therapy appears to have a high potential not only for the treatment of gliomas, the most common brain tumors, but also in other tumors
- The ability of endostatin to inhibit neoangiogenesis is mediated, at least in part, by Zn^+2 binding and elastase processing
- Widespread endostatin expression was found in elactic fibers in vessel walls and in some other basement membrane zones
- Endostatin is released by neurons to accumulate in amyloid plaques in Alzheimer's disease.
Compare Similar Items
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Antigen: Endostatin
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P39060
Gene Symbols: COL18A1
Immunogen: Recombinant human Endostatin
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: 1837-46
Conjugate: Unconjugated
Gene: COL18A1
Gene Alias: antiangiogenic agent; Col18a1; Collagen alpha-1(XVIII) chain; collagen type XVIII alpha 1 chain; collagen, type XVIII, alpha 1; endostatin; FLJ27325; FLJ34914; KNO; KNO1; KS; MGC74745; multi-functional protein MFP; NC1; Non-collagenous domain 1; procollagen, type XVIII, alpha 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 80781
Content And Storage: 4° C
Form: Liquid
Antigen:
Endostatin
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P39060
Gene Symbols:
COL18A1
Immunogen:
Recombinant human Endostatin
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
1837-46
Conjugate:
Unconjugated
Gene:
COL18A1
Gene Alias:
antiangiogenic agent; Col18a1; Collagen alpha-1(XVIII) chain; collagen type XVIII alpha 1 chain; collagen, type XVIII, alpha 1; endostatin; FLJ27325; FLJ34914; KNO; KNO1; KS; MGC74745; multi-functional protein MFP; NC1; Non-collagenous domain 1; procollagen, type XVIII, alpha 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
80781
Content And Storage:
4° C
Form:
Liquid
Antigen: RECA-1
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Cell surface antigen.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: RECA-1
Conjugate: Unconjugated
Gene: __
Gene Alias: Reca1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C
Form: Liquid
Antigen:
RECA-1
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Cell surface antigen.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
RECA-1
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Reca1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C
Form:
Liquid
Antigen: Caveolin 1
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P41350
Gene Symbols: CAV1
Immunogen: Rat caveolin-1
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 7C8
Conjugate: Unconjugated
Gene: CAV1
Gene Alias: BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 25404
Content And Storage: 4° C
Form: Liquid
Antigen:
Caveolin 1
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P41350
Gene Symbols:
CAV1
Immunogen:
Rat caveolin-1
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
7C8
Conjugate:
Unconjugated
Gene:
CAV1
Gene Alias:
BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
25404
Content And Storage:
4° C
Form:
Liquid
Antigen: ASGR1
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P02706, P07306
Gene Symbols: Asgr1
Immunogen: Crude rat liver membrane extracts
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
Clone: 8D7
Conjugate: Unconjugated
Gene: Asgr1
Gene Alias: ASGPR; ASGPR 1; ASGP-R 1; ASGPR1; ASGR; ASGR1; Asgr-1; asialoglycoprotein receptor (RHL1); asialoglycoprotein receptor 1; Asialoglycoprotein receptor 1 (hepatic lectin); asialoglycoprotein receptor RHL1; CLEC4H1; C-type lectin domain family 4 member H1; Hepatic lectin 1; hepatic lectin 1 RHL1; hepatic lectin 1, RHL1; hepatic lectin H1; HL-1; RATRHL1; RHL1; RHL-1; Unknown (protein for MGC:133691)
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 24210, 432
Content And Storage: 4° C
Form: Liquid
Antigen:
ASGR1
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P02706, P07306
Gene Symbols:
Asgr1
Immunogen:
Crude rat liver membrane extracts
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
Clone:
8D7
Conjugate:
Unconjugated
Gene:
Asgr1
Gene Alias:
ASGPR; ASGPR 1; ASGP-R 1; ASGPR1; ASGR; ASGR1; Asgr-1; asialoglycoprotein receptor (RHL1); asialoglycoprotein receptor 1; Asialoglycoprotein receptor 1 (hepatic lectin); asialoglycoprotein receptor RHL1; CLEC4H1; C-type lectin domain family 4 member H1; Hepatic lectin 1; hepatic lectin 1 RHL1; hepatic lectin 1, RHL1; hepatic lectin H1; HL-1; RATRHL1; RHL1; RHL-1; Unknown (protein for MGC:133691)
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
24210, 432
Content And Storage:
4° C
Form:
Liquid