01-676-584

RAP1 Monoclonal Antibody (78B356.1), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-676-584-Each-of-1 In Stock ₹ 45,646.26

01-676-584 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

RAP1

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.2% gelatin and 0.02% sodium azide

Gene Accession No.

Q9NYB0

Gene Symbols

TERF2IP

Immunogen

Synthetic peptide corresponding residues 212-235 of human Rap1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

78B356.1

Conjugate

Unconjugated

Gene

TERF2IP

Gene Alias

dopamine receptor interacting protein 5; dopamine receptor-interacting protein 5; DRIP5; hRap1; MNCb-0448; MNCb-0628; PP8000; RAP1; RAP1 homolog; repressor/activator protein 1 homolog; tel; telomeric repeat binding factor 2, interacting protein; telomeric repeat-binding factor 2-interacting protein 1; TERF2 interacting protein; TERF21P; TERF2-interacting telomeric protein 1; TERF2IP; TRF2-interacting telomeric protein 1; TRF2-interacting telomeric protein Rap1; TRF2-interacting telomeric RAP1 protein

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

54386

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Suggested positive control: 293 whole cell lysate, antigen standard for TERF2IP (transient overexpression lysate)
  • Human Rap1 was the first identified ortholog of the yeast telomeric protein scRap1, which shares 3 conserved sequence motifs in common
  • HRap1 is located at telomeres and affects telomere length by being recruited to telomeres by TRF2 instead of directly binding to the telomere like scRap1
  • The hRap1 cDNA codes for a protein of 399 amino acids with approximate molecular weight of 47 kDa
  • The hRap1 protein does not interact with TRF1
  • TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length(1)
  • TRF2, like TRF1 contains a Myb-related DNA binding motif
  • It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes
  • TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini
  • The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells
  • Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types.

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Img

Thermo Scientific

01-676-584

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Antigen:
RAP1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.2% gelatin and 0.02% sodium azide

Gene Accession No.:
Q9NYB0

Gene Symbols:
TERF2IP

Immunogen:
Synthetic peptide corresponding residues 212-235 of human Rap1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
78B356.1

Conjugate:
Unconjugated

Gene:
TERF2IP

Gene Alias:
dopamine receptor interacting protein 5; dopamine receptor-interacting protein 5; DRIP5; hRap1; MNCb-0448; MNCb-0628; PP8000; RAP1; RAP1 homolog; repressor/activator protein 1 homolog; tel; telomeric repeat binding factor 2, interacting protein; telomeric repeat-binding factor 2-interacting protein 1; TERF2 interacting protein; TERF21P; TERF2-interacting telomeric protein 1; TERF2IP; TRF2-interacting telomeric protein 1; TRF2-interacting telomeric protein Rap1; TRF2-interacting telomeric RAP1 protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
54386

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-586

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Antigen:
KappaB ras1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.2% gelatin and 0.05% sodium azide

Gene Accession No.:
Q8CEC5, Q9NYS0

Gene Symbols:
NKIRAS1, nkiras1.S

Immunogen:
Synthetic peptide corresponding to residues 96-113 of human kB-Ras1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Equine, Human, Mouse, Non-human Primate, Porcine, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
184C278

Conjugate:
Unconjugated

Gene:
NKIRAS1

Gene Alias:
2400004O09Rik; C15orf1; I1PP2A; I-kappa-B-interacting Ras-like protein 1; kappa B-ras 1; kappa B-Ras protein 1; kappaB-Ras1; KBRAS1; LANP; MAPM; MGC119787; MGC150373; NF-kappa-B inhibitor-interacting Ras-like protein 1; NFKB inhibitor interacting Ras like 1; NFKB inhibitor interacting Ras-like 1; NFKB inhibitor interacting Ras-like 1 S homeolog; NFKB inhibitor interacting Ras-like protein 1; Nkiras1; nkiras1.S; PHAP1; PHAPI; PP32; XELAEV_18033117mg

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100036787, 100051752, 100620195, 28512, 305751, 477047, 522875, 69721

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-587

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Antigen:
D4-GDI

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.02% gelatin and 0.02% sodium azide

Gene Accession No.:
P52566

Gene Symbols:
ARHGDIB

Immunogen:
Synthetic peptide corresponding to a portion of human D4-GDI.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
10D774

Conjugate:
Unconjugated

Gene:
ARHGDIB

Gene Alias:
ARHGDIB; D4; d4 gdi; GDI LYGDI; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; Rho GDP dissociation inhibitor beta; rho GDP-dissociation inhibitor 2; Rho, GDP dissociation inhibitor (GDI) beta; rho-GDI beta; RhoGDI2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
397

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-588

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Antigen:
Rb (Cleaved DRb-p70)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
P06400, P13405

Gene Symbols:
RB1

Immunogen:
Caspase-3-induced cleavage site of human Rb.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
172C1094

Conjugate:
Unconjugated

Gene:
RB1

Gene Alias:
Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p105-Rb; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; Rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; retinoblastoma 1; retinoblastoma suspectibility protein; retinoblastoma-associated protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
19645, 5925

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid