01-676-592
LCK Monoclonal Antibody (33D196), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-592-Each-of-1 | In Stock | ₹ 45,304.02 |
01-676-592 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,304.02
GST (18%): ₹ 8,154.724
Total Price: ₹ 53,458.744
Antigen
LCK
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P06239, P06240
Gene Symbols
LCK
Immunogen
Human lck protein.
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
33D196
Conjugate
Unconjugated
Gene
LCK
Gene Alias
EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
16818, 3932
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Description
- The immunogen sequence is 100% homologus in mouse
- Suggested positive control: Jurkat whole cell lysate
- LCK is a member of the Src-family tyrosine kinase, which are essential for signaling through the T-cell receptor (TCR) complex
- Upon TCR triggering, LCK phosphorylates the ITAM motives in its zeta subunits establishing binding sites for the SH2 domains of the tyrosine kinase ZAP70, which is also phosphorylated by LCK and activated to generate subsequent signaling platforms by phosphorylation of adaptor LAT
- The majority of LCK is localized to the plasma membrane, however, there is also a significant fraction associated with the Golgi apparatus which may contribute to Raf activation under conditions of weak stimulation through the TCR
- LCK contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively
- LCK is also involved in the regulation of apoptosis induced by various stimuli, but not by the death receptors
- Diseases associated with LCK include Immunodeficiency 22 and CD45 deficiency
- Alternatively splice variants of the LCK gene encoding different isoforms of the protein have been found.
Compare Similar Items
Show Difference
Antigen: LCK
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P06239, P06240
Gene Symbols: LCK
Immunogen: Human lck protein.
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: 33D196
Conjugate: Unconjugated
Gene: LCK
Gene Alias: EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 16818, 3932
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
LCK
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P06239, P06240
Gene Symbols:
LCK
Immunogen:
Human lck protein.
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
33D196
Conjugate:
Unconjugated
Gene:
LCK
Gene Alias:
EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
16818, 3932
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Smallpox Virus B5R
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Within the range of amino acids 33-62 of the B5R protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG1 κ
Applications: Western Blot
Clone: 1J2F3
Conjugate: Unconjugated
Gene: __
Gene Alias: __
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Smallpox Virus B5R
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Within the range of amino acids 33-62 of the B5R protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
1J2F3
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: PMS2
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P54278, P54279
Gene Symbols: PMS2
Immunogen: A synthetic peptide corresponding to amino acids 623-639 SSLAKRIKQLHHEAQQS of human PMS2
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: 163C1251
Conjugate: Unconjugated
Gene: PMS2
Gene Alias: AW555130; DNA mismatch repair protein PMS2; H_DJ0042M02.9; HNPCC4; mismatch repair endonuclease PMS2; MLH4; PMS1 homolog 2, mismatch repair protein; PMS1 homolog 2, mismatch repair system component; PMS1 protein homolog 2; PMS2; PMS2 postmeiotic segregation increased 2; PMS2 postmeiotic segregation increased 2 (S. cerevisiae); PMS2CL; PMSL2; postmeiotic segregation increased 2; postmeiotic segregation increased 2 (S. cerevisiae); postmeiotic segregation increased 2 nirs variant 6
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 18861, 5395
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
PMS2
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P54278, P54279
Gene Symbols:
PMS2
Immunogen:
A synthetic peptide corresponding to amino acids 623-639 SSLAKRIKQLHHEAQQS of human PMS2
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
163C1251
Conjugate:
Unconjugated
Gene:
PMS2
Gene Alias:
AW555130; DNA mismatch repair protein PMS2; H_DJ0042M02.9; HNPCC4; mismatch repair endonuclease PMS2; MLH4; PMS1 homolog 2, mismatch repair protein; PMS1 homolog 2, mismatch repair system component; PMS1 protein homolog 2; PMS2; PMS2 postmeiotic segregation increased 2; PMS2 postmeiotic segregation increased 2 (S. cerevisiae); PMS2CL; PMSL2; postmeiotic segregation increased 2; postmeiotic segregation increased 2 (S. cerevisiae); postmeiotic segregation increased 2 nirs variant 6
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
18861, 5395
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: MLH1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.: P40692
Gene Symbols: Mlh1
Immunogen: A synthetic peptide corresponding to amino acids 387-403 DSREQKLDAFLQPLSKP of human MLH1
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Western Blot
Clone: 164C819
Conjugate: Unconjugated
Gene: Mlh1
Gene Alias: 1110035C23Rik; AI317206; AI325952; AI561766; COCA2; colon cancer, nonpolyposis type 2; DNA mismatch repair protein Mlh1; DNA mismatch repair protein Mlh1-like protein; FCC2; hMLH1; HNPCC; HNPCC2; I79_014127; MGC5172; mismatch repair protein 1; MLH1; MLH-1; mutL homolog 1; mutL homolog 1 (E. coli); mutL homolog 1, colon cancer, nonpolyposis type 2; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); mutL protein homolog 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4292
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MLH1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.:
P40692
Gene Symbols:
Mlh1
Immunogen:
A synthetic peptide corresponding to amino acids 387-403 DSREQKLDAFLQPLSKP of human MLH1
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
164C819
Conjugate:
Unconjugated
Gene:
Mlh1
Gene Alias:
1110035C23Rik; AI317206; AI325952; AI561766; COCA2; colon cancer, nonpolyposis type 2; DNA mismatch repair protein Mlh1; DNA mismatch repair protein Mlh1-like protein; FCC2; hMLH1; HNPCC; HNPCC2; I79_014127; MGC5172; mismatch repair protein 1; MLH1; MLH-1; mutL homolog 1; mutL homolog 1 (E. coli); mutL homolog 1, colon cancer, nonpolyposis type 2; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); mutL protein homolog 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4292
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid