01-676-621

FOXP3 Monoclonal Antibody (3G3), FITC, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-676-621-Each-of-1 In Stock ₹ 49,582.02

01-676-621 - Each of 1

₹ 49,582.02

In Stock

Quantity

1

Base Price: ₹ 49,582.02

GST (18%): ₹ 8,924.764

Total Price: ₹ 58,506.784

Antigen

FOXP3

Classification

Monoclonal

Concentration

1.85 mg/mL

Formulation

50mM sodium borate with 0.05% sodium azide

Gene Accession No.

Q99JB6, Q9BZS1

Gene Symbols

Foxp3

Immunogen

Full-length, His-tagged murine FOXP3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

3G3

Conjugate

FITC

Gene

Foxp3

Gene Alias

AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

20371, 50943

Content And Storage

4° C, store in dark

Form

Liquid

Description

  • MA1-41628 is derived from full-length His-tagged mouse FOXP3
  • The precise epitope is not known, but it has been mapped to the N-terminal portion of the protein
  • FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis
  • FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells
  • FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells
  • Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice
  • In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome
  • Transcript variants of FOXP3 encoding different isoforms have been identified
  • In human breast and colon cancer cells, expression of FOXP3 is regulated by p53 in response to the DNA damage.

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Thermo Scientific

01-676-621

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Antigen:
FOXP3

Classification:
Monoclonal

Concentration:
1.85 mg/mL

Formulation:
50mM sodium borate with 0.05% sodium azide

Gene Accession No.:
Q99JB6, Q9BZS1

Gene Symbols:
Foxp3

Immunogen:
Full-length, His-tagged murine FOXP3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
3G3

Conjugate:
FITC

Gene:
Foxp3

Gene Alias:
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20371, 50943

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Thermo Scientific

01-676-626

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Antigen:
MUTYH

Classification:
Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.02% sodium azide

Gene Accession No.:
Q8R5G2, Q99P21, Q9UIF7

Gene Symbols:
MUTYH

Immunogen:
A synthetic peptide corresponding to amino acids 531-546 of human MYH.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bacteria, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
MUTYH

Gene Alias:
5730495A01Rik; A/G-specific adenine DNA glycosylase; adenine DNA glycosylase; adenine-DNA glycosylase; hMYH; MGC4416; mMYH; mutY DNA glycosylase; mutY homolog; mutY homolog (E. coli); mutY homolog alpha; Mutyh; Mutyha; Mutyhalpha; Mutyhb; Mutyhbeta; Mutyhc; mutY-like protein; Myh; OTTHUMP00000009098; OTTHUMP00000009102; rMYH; RP4-534D1.2; the full-length form type A, 5' region

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
170841, 4595, 70603

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-628

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Antigen:
MECP2

Classification:
Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.2% gelatin and 0.05% sodium azide

Gene Accession No.:
P51608, Q9Z2D6

Gene Symbols:
Mecp2

Immunogen:
Synthetic peptides corresponding to residues 11-25 and 181-195 of human MeCP2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
Mecp2

Gene Alias:
1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
17257, 4204

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-630

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Antigen:
TRAF6

Classification:
Polyclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9Y4K3

Gene Symbols:
TRAF6

Immunogen:
Synthetic peptide corresponding to residues 410-460 of human TRAF6.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
TRAF6

Gene Alias:
2310003F17Rik; AI851288; C630032O20Rik; E3 ubiquitin-protein ligase TRAF6; interleukin-1 signal transducer; MGC:3310; RING finger protein 85; RING-type E3 ubiquitin transferase TRAF6; RNF85; TNF receptor associated factor 6; TNF receptor-associated factor 6; TNF receptor-associated factor 6, E3 ubiquitin protein ligase; Traf6

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
7189

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid