01-676-631

SOCS1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-676-631-Each-of-1 In Stock ₹ 47,015.22

01-676-631 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

SOCS1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Socs1

Gene Alias

CIS1; Cish1; Cish7; cytokine inducible SH2-containing protein 1; cytokine inducible SH2-containing protein 7; cytokine-inducible SH2 protein 1; JAB; JAK binding protein; JAK2-binding protein; JAK-binding protein; Socs1; SOCS-1; SSI1; SSI-1; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; Suppressor of cytokine signaling 1; Tec-interacting protein 3; TIP3; TIP-3

Host Species

Rabbit

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum diluted in PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.

O15524, O35716

Gene Symbols

Socs1

Immunogen

Synthetic peptide corresponding to residues 54-68 of human SOCS1 protein.

Regulatory Status

RUO

Gene ID (Entrez)

12703, 8651

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Suggested positive control: Ramos or RAW
  • The Suppressor of cytokine signaling (SOCS) and cytokine-inducible SH2 proteins are a family of intracellular proteins which regulate the immune cell responses to cytokines
  • SOCS1 acts to suppress dendritic cell (DC) as well as T cell hyperactivation following cytokine signaling by inhibiting JAK tyrosine kinase, a kinase necessary for type I and II cytokine receptors to initiate signaling, by directly binding to the catalytic domain of the kinase
  • SOCS1 also possesses E3 ubiquitin protein ligase activity that results in the polyubiquitination of its target proteins and subsequent degradation by the proteosome
  • It is through this method that SOCS1 negatively regulates signaling by Toll-like receptors TLR2 and TLR4 by mediating the degradation of the TLR signaling adaptor protein TIRAP.

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Thermo Scientific

01-676-631

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Antigen:
SOCS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Socs1

Gene Alias:
CIS1; Cish1; Cish7; cytokine inducible SH2-containing protein 1; cytokine inducible SH2-containing protein 7; cytokine-inducible SH2 protein 1; JAB; JAK binding protein; JAK2-binding protein; JAK-binding protein; Socs1; SOCS-1; SSI1; SSI-1; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; Suppressor of cytokine signaling 1; Tec-interacting protein 3; TIP3; TIP-3

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum diluted in PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O15524, O35716

Gene Symbols:
Socs1

Immunogen:
Synthetic peptide corresponding to residues 54-68 of human SOCS1 protein.

Regulatory Status:
RUO

Gene ID (Entrez):
12703, 8651

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-633

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Antigen:
GREM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Grem1

Gene Alias:
C15DUPq; Cell proliferation-inducing gene 2 protein; CKTSF1B1; colorectal adenoma and carcinoma 1; CRAC1; CRCS4; Cysteine knot superfamily 1, BMP antagonist 1; DAN domain family member 2; DAND2; Down-regulated in Mos-transformed cells protein; down-regulated in v-mos-transformed cells; Drm; DUP15q; Grem; GREM1; gremlin; gremlin 1; gremlin 1 homolog, cysteine knot superfamily; gremlin 1, cysteine knot superfamily, homolog; gremlin 1, DAN family BMP antagonist; gremlin 1-like protein; gremlin-1; HMPS; HMPS1; IHG-2; Increased in high glucose protein 2; increased in high glucose-2; ld; MPSH; PIG2

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O60565

Gene Symbols:
Grem1

Immunogen:
Synthetic peptide coorresponding to residues Q(52) P G S R N R G R G Q G R G T A(67) of human CKTSF1B1.

Regulatory Status:
RUO

Gene ID (Entrez):
26585

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-636

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Antigen:
TRIB3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIB3

Gene Alias:
C20orf97; DJ1103G7.3; Ifld2; induced in fatty liver dystrophy 2; kinase; Neuronal cell death Inducible Putative Kinase; neuronal cell death-inducible putative kinase; Nipk; p65-interacting inhibitor of NF-kappaB; p65-interacting inhibitor of NF-kappa-B; SINK; SKIP3; Trb3; TRB-3; TRIB3; Tribbles 3; Tribbles homolog 3; tribbles homolog 3 (Drosophila); tribbles pseudokinase 3

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q96RU7

Gene Symbols:
TRIB3

Immunogen:
Synthetic peptide corresponding to residues 315-332 of human TRIB3.

Regulatory Status:
RUO

Gene ID (Entrez):
57761

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-639

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Antigen:
SMAD6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMAD6

Gene Alias:
AOVD2; b2b390Clo; HsT17432; MAD homolog 6; mad homolog 7; Madh6; Madh7; Mothers against decapentaplegic homolog 6; mothers against decapentaplegic, drosophila, homolog of, 6; mothers against DPP homolog 6; Msmad6; SMAD; SMAD 6; SMAD family member 6; SMAD SMAD; SMAD, mothers against DPP homolog 6; SMAD6

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Ovine, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O35182, O43541

Gene Symbols:
SMAD6

Immunogen:
Synthetic peptide made to an internal portion of human SMAD6 (between amino acids 30-150) [UniProt O43541].

Regulatory Status:
RUO

Gene ID (Entrez):
101103068, 17130, 367100, 4091

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid