01-676-898
CD11a Monoclonal Antibody (87-6F9), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-898-Each-of-1 | In Stock | ₹ 44,533.98 |
01-676-898 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,533.98
GST (18%): ₹ 8,016.116
Total Price: ₹ 52,550.096
Antigen
CD11a
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P20701
Gene Symbols
ITGAL
Immunogen
CD11a antigen.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
Flow Cytometry, Immunohistochemistry (Frozen)
Clone
87-6F9
Conjugate
Unconjugated
Gene
ITGAL
Gene Alias
(p180); alpha L integrin; antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; antigen CD11A p180; CD11 antigen-like family member A; CD11a; integrin alpha L; integrin alphaL; integrin alpha-L; integrin alpha-L precursor; integrin gene promoter; integrin subunit alpha L; integrin surface receptor; integrin, alpha L; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte antigen 15; lymphocyte function associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen-1
Host Species
Mouse
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
3683
Content And Storage
4° C
Form
Liquid
Description
- CD11a (LFA-1 alpha, ITGAL) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin
- CD11a is implicated in activation of LFA-1 complex
- CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling
- CD11a is expressed on the plasma membrane of leukocytes in a low-affinity conformation
- Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of CD11a to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3
- CD11a is thus involved in interaction of various immune cells and in their tissue-specific settlement, but participates also in control of cell differentiation and proliferation and of T-cell effector functions
- Blocking of CD11a function by specific antibodies or small molecules has become an important therapeutic approach in treatment of multiple inflammatory diseases
- For example, humanized anti- CD11a antibody Efalizumab (Raptiva) is being used to interfere with T cell migration to sites of inflammation, binding of cholesterol-lowering drug simvastatin to CD11a allosteric site leads to immunomodulation and increase in lymphocytic cholinergic activity
- Two transcript variants encoding different isoforms of CD11a have been found
- Diseases associated with CD11a dysfunction include benign cephalic histiocytosis and leukocyte adhesion deficiency.
Compare Similar Items
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Antigen: CD11a
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P20701
Gene Symbols: ITGAL
Immunogen: CD11a antigen.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry, Immunohistochemistry (Frozen)
Clone: 87-6F9
Conjugate: Unconjugated
Gene: ITGAL
Gene Alias: (p180); alpha L integrin; antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; antigen CD11A p180; CD11 antigen-like family member A; CD11a; integrin alpha L; integrin alphaL; integrin alpha-L; integrin alpha-L precursor; integrin gene promoter; integrin subunit alpha L; integrin surface receptor; integrin, alpha L; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte antigen 15; lymphocyte function associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen-1
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 3683
Content And Storage: 4° C
Form: Liquid
Antigen:
CD11a
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P20701
Gene Symbols:
ITGAL
Immunogen:
CD11a antigen.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunohistochemistry (Frozen)
Clone:
87-6F9
Conjugate:
Unconjugated
Gene:
ITGAL
Gene Alias:
(p180); alpha L integrin; antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; antigen CD11A p180; CD11 antigen-like family member A; CD11a; integrin alpha L; integrin alphaL; integrin alpha-L; integrin alpha-L precursor; integrin gene promoter; integrin subunit alpha L; integrin surface receptor; integrin, alpha L; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte antigen 15; lymphocyte function associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen-1
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
3683
Content And Storage:
4° C
Form:
Liquid
Antigen: CD11c
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites diluted in PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P20702
Gene Symbols: Itgax
Immunogen: AML blasts.
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry
Clone: FK24
Conjugate: Unconjugated
Gene: Itgax
Gene Alias: AI449405; CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement component 3 receptor 4 subunit; complement receptor 4; Cr4; integrin alpha X; integrin alpha-X; integrin aX; integrin subunit alpha X; integrin, alpha X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Itgax; Leu M5; leu M5, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; N418; p150 95 integrin alpha chain; RGD1561123; SLEB6
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 3687
Content And Storage: 4° C
Form: Liquid
Antigen:
CD11c
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites diluted in PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P20702
Gene Symbols:
Itgax
Immunogen:
AML blasts.
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry
Clone:
FK24
Conjugate:
Unconjugated
Gene:
Itgax
Gene Alias:
AI449405; CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement component 3 receptor 4 subunit; complement receptor 4; Cr4; integrin alpha X; integrin alpha-X; integrin aX; integrin subunit alpha X; integrin, alpha X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Itgax; Leu M5; leu M5, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; N418; p150 95 integrin alpha chain; RGD1561123; SLEB6
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
3687
Content And Storage:
4° C
Form:
Liquid
Antigen: CD13
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with BSA and 0.1% sodium azide
Gene Accession No.: P15144, P15684, P97449
Gene Symbols: ANPEP
Immunogen: CD13.
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human, Mammalia, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry
Clone: Tük 1
Conjugate: FITC
Gene: ANPEP
Gene Alias: alanyl (membrane) aminopeptidase; alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150); alanyl aminopeptidase; alanyl aminopeptidase, membrane; aminopeptidase; aminopeptidase Ey; Aminopeptidase M; aminopeptidase N; aminopeptidase N.; aminopeptidase N/CD13; Anpep; APDE; Apm; AP-M; APN; AP-N; bAPN; cAPN; Cd13; cluster of differentiation antigen 13 (CD13); fAPN; gp130; gp150; h AP-N; hAPN; kidney aminopeptidase M; kidney Zn peptidase; KZP; Lap1; Lap-1; leucine arylaminopeptidase 1; LOW QUALITY PROTEIN: aminopeptidase N; membrane alanine aminiopeptidase; membrane alanine aminopeptidase; membrane alanyl aminopeptidase; membrane protein p161; Microsomal aminopeptidase; myeloid plasma membrane glycoprotein CD13; p150; pAPN; PEPN; porcine aminopeptidase N; rAPN; rbAPN; Unknown (protein for MGC:126949)
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 16790, 290, 81641
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
CD13
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with BSA and 0.1% sodium azide
Gene Accession No.:
P15144, P15684, P97449
Gene Symbols:
ANPEP
Immunogen:
CD13.
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human, Mammalia, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
Tük 1
Conjugate:
FITC
Gene:
ANPEP
Gene Alias:
alanyl (membrane) aminopeptidase; alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150); alanyl aminopeptidase; alanyl aminopeptidase, membrane; aminopeptidase; aminopeptidase Ey; Aminopeptidase M; aminopeptidase N; aminopeptidase N.; aminopeptidase N/CD13; Anpep; APDE; Apm; AP-M; APN; AP-N; bAPN; cAPN; Cd13; cluster of differentiation antigen 13 (CD13); fAPN; gp130; gp150; h AP-N; hAPN; kidney aminopeptidase M; kidney Zn peptidase; KZP; Lap1; Lap-1; leucine arylaminopeptidase 1; LOW QUALITY PROTEIN: aminopeptidase N; membrane alanine aminiopeptidase; membrane alanine aminopeptidase; membrane alanyl aminopeptidase; membrane protein p161; Microsomal aminopeptidase; myeloid plasma membrane glycoprotein CD13; p150; pAPN; PEPN; porcine aminopeptidase N; rAPN; rbAPN; Unknown (protein for MGC:126949)
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
16790, 290, 81641
Content And Storage:
4° C, store in dark
Form:
Liquid
Antigen: SSEA1
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P22083
Gene Symbols: FUT4
Immunogen: Erythroid-myeloid leukemia cell line K562.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: BRA4F1
Conjugate: Unconjugated
Gene: FUT4
Gene Alias: FUTIV, Lewis X, SSEA-1
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 2526
Content And Storage: 4° C
Form: Liquid
Antigen:
SSEA1
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P22083
Gene Symbols:
FUT4
Immunogen:
Erythroid-myeloid leukemia cell line K562.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
BRA4F1
Conjugate:
Unconjugated
Gene:
FUT4
Gene Alias:
FUTIV, Lewis X, SSEA-1
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
2526
Content And Storage:
4° C
Form:
Liquid