01-950-113
Estrogen Receptor beta Monoclonal Antibody (14C8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-950-113-Each-of-1 | In Stock | ₹ 51,507.12 |
01-950-113 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,507.12
GST (18%): ₹ 9,271.282
Total Price: ₹ 60,778.402
Antigen
Estrogen Receptor beta
Classification
Monoclonal
Concentration
1.23 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
O08537, Q92731
Gene Symbols
ESR2
Immunogen
Recombinant protein corresponding to residues 1-153 of human ER beta, expressed in E. coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate
Product Type
Antibody
Isotype
IgG2b
Applications
ChIP Assay, Dot Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
14C8
Conjugate
Unconjugated
Gene
ESR2
Gene Alias
ER; ER beta; ER[b]; Erb; Erb2; Erbeta; ER-beta; Esr2; ESRB; ESR-BETA; ESTRB; estrogen receptor 2; estrogen receptor 2 (beta); estrogen receptor 2 (ER beta); estrogen receptor 2 beta; estrogen receptor beta; estrogen receptor beta 1 isoform deletion variant; estrogen receptor beta 4; NR3A2; Nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta; steroid receptor
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
13983, 2100
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- For immunostaining, strong ER beta staining in epithelial cell nuclei is observed, with weak to moderate staining seen in surrounding stromal and endothelial cell nuclei, and sporadic light cytoplasmic staining
- It has also been reported that this antibody has been used to detect ERb in colon and ovarian tumors
- Positive control of recombinant fusion protein
- Estrogen Receptor beta (ER beta, NR3A2) protein is approximately 55kD, though multiple isoforms ranging from 36-59kD have been described
- Human ER beta was initially cloned and characterized from testis
- Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
- The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
- When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
- There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
- Estrogen receptor beta (ER beta) binds estrogens with an affinity similar to that of estrogen receptor alpha
- Some ER beta isoforms dominantly inhibit the activity of estrogen receptor alpha in reproductive tissues
- ER beta is found widely in many tissues throughout the body and can act as a potent tumor suppressor, playing a crucial role in many cancer types such as prostate cancer, autism spectrum disorder, medullary thyroid carcinoma, De Quervain Disease and risk of cardiovascular disease.
Compare Similar Items
Show Difference
Antigen: Estrogen Receptor beta
Classification: Monoclonal
Concentration: 1.23 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O08537, Q92731
Gene Symbols: ESR2
Immunogen: Recombinant protein corresponding to residues 1-153 of human ER beta, expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate
Product Type: Antibody
Isotype: IgG2b
Applications: ChIP Assay, Dot Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 14C8
Conjugate: Unconjugated
Gene: ESR2
Gene Alias: ER; ER beta; ER[b]; Erb; Erb2; Erbeta; ER-beta; Esr2; ESRB; ESR-BETA; ESTRB; estrogen receptor 2; estrogen receptor 2 (beta); estrogen receptor 2 (ER beta); estrogen receptor 2 beta; estrogen receptor beta; estrogen receptor beta 1 isoform deletion variant; estrogen receptor beta 4; NR3A2; Nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta; steroid receptor
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 13983, 2100
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Estrogen Receptor beta
Classification:
Monoclonal
Concentration:
1.23 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O08537, Q92731
Gene Symbols:
ESR2
Immunogen:
Recombinant protein corresponding to residues 1-153 of human ER beta, expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate
Product Type:
Antibody
Isotype:
IgG2b
Applications:
ChIP Assay, Dot Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
14C8
Conjugate:
Unconjugated
Gene:
ESR2
Gene Alias:
ER; ER beta; ER[b]; Erb; Erb2; Erbeta; ER-beta; Esr2; ESRB; ESR-BETA; ESTRB; estrogen receptor 2; estrogen receptor 2 (beta); estrogen receptor 2 (ER beta); estrogen receptor 2 beta; estrogen receptor beta; estrogen receptor beta 1 isoform deletion variant; estrogen receptor beta 4; NR3A2; Nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta; steroid receptor
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
13983, 2100
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Aromatase
Classification: Polyclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.5% BSA, 30% glycerol, 5mM EDTA and 0.03% ProClin 300; pH 7.2
Gene Accession No.: O46512, P11511, P19098, P22443, P28649, P46194, Q29605, Q29624
Gene Symbols: Cyp19a1
Immunogen: Synthetic peptide surrounding amino acid 385 of human Aromatase
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Bovine, Chicken, Equine, Human, Mouse, Porcine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: __
Conjugate: Unconjugated
Gene: Cyp19a1
Gene Alias: Ar; ArKO; ARO; ARO1; Arom; Aromatase; aromatase 1; aromatase cytochrome P450; aromatase cytochrome P450 19A1; CPV1; CYAR; Cyp19; Cyp19a; Cyp19a1; CYP19P1; CYPXIX; CYPXIXA1; Cytochrome P450 17-alpha; cytochrome P450 19 type I; Cytochrome P450 19A1; cytochrome P450 aromatase; cytochrome P-450 aromatase; cytochrome P-450 aromatase (alt.); cytochrome P450 family 19 subfamily a; cytochrome P450 family 19 subfamily A member 1; Cytochrome P450, 19, aromatase; cytochrome P450, family 17, subfamily A, polypeptide 1; cytochrome P450, family 19, subfamily A, polypeptide 1; cytochrome P450, family XIX (conversion of androgen to estrogen), aromatase; cytochrome P450, family19, subfamily A, polypeptide 1; cytochrome P450, subfamily 19; cytochrome P450, subfamily XIX (aromatization of androgens); cytochrome P-450AROM; estrogen synthase; estrogen synthetase; flavoprotein-linked monooxygenase; Int5; Int-5; MGC104309; microsomal monooxygenase; P450AROM; P-450AROM; type III cytochrome p450 aromatase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100009712, 100328545, 13075, 1588, 25147, 281740, 403331, 414854
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Aromatase
Classification:
Polyclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.5% BSA, 30% glycerol, 5mM EDTA and 0.03% ProClin 300; pH 7.2
Gene Accession No.:
O46512, P11511, P19098, P22443, P28649, P46194, Q29605, Q29624
Gene Symbols:
Cyp19a1
Immunogen:
Synthetic peptide surrounding amino acid 385 of human Aromatase
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Chicken, Equine, Human, Mouse, Porcine, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
Cyp19a1
Gene Alias:
Ar; ArKO; ARO; ARO1; Arom; Aromatase; aromatase 1; aromatase cytochrome P450; aromatase cytochrome P450 19A1; CPV1; CYAR; Cyp19; Cyp19a; Cyp19a1; CYP19P1; CYPXIX; CYPXIXA1; Cytochrome P450 17-alpha; cytochrome P450 19 type I; Cytochrome P450 19A1; cytochrome P450 aromatase; cytochrome P-450 aromatase; cytochrome P-450 aromatase (alt.); cytochrome P450 family 19 subfamily a; cytochrome P450 family 19 subfamily A member 1; Cytochrome P450, 19, aromatase; cytochrome P450, family 17, subfamily A, polypeptide 1; cytochrome P450, family 19, subfamily A, polypeptide 1; cytochrome P450, family XIX (conversion of androgen to estrogen), aromatase; cytochrome P450, family19, subfamily A, polypeptide 1; cytochrome P450, subfamily 19; cytochrome P450, subfamily XIX (aromatization of androgens); cytochrome P-450AROM; estrogen synthase; estrogen synthetase; flavoprotein-linked monooxygenase; Int5; Int-5; MGC104309; microsomal monooxygenase; P450AROM; P-450AROM; type III cytochrome p450 aromatase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100009712, 100328545, 13075, 1588, 25147, 281740, 403331, 414854
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: VEGF
Classification: Polyclonal
Concentration: 0.2 mg/mL
Formulation: 10mM PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.: P15692, P16612, Q00731
Gene Symbols: VEGFA
Immunogen: Human recombinant VEGF 165.
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin)
Clone: __
Conjugate: Unconjugated
Gene: VEGFA
Gene Alias: angiogenic factor; etID309976.16; eVEGF120; eVEGF164; human VEGF121 homolog; MGC70609; MVCD1; ovine vascular endothelial growth factor; RP1-261G23.1; unnamed protein product; VAS; vascular endothelial growth factor; vascular endothelial growth factor (VEGF) precursor; vascular endothelial growth factor 121 isoform; vascular endothelial growth factor 164; vascular endothelial growth factor 165b; vascular endothelial growth factor 182; vascular endothelial growth factor 182 isoform; vascular endothelial growth factor 188; vascular endothelial growth factor 188 isoform; vascular endothelial growth factor 189; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular endothelial growth factor Aa; Vascular endothelial growth factor A-A; vascular endothelial growth factor isoform 165; vascular permeability factor; Vasculotropin; VEGF; VEGF1; VEGF164; VEGF182; VEGF188; vegfa; VEGF-A; VEGFA165b; vegfaa; VEGF-A-A; VEGFMGC70609; VPF; VPF ant; wu:fj82c06
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 22339, 7422, 83785
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
VEGF
Classification:
Polyclonal
Concentration:
0.2 mg/mL
Formulation:
10mM PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P15692, P16612, Q00731
Gene Symbols:
VEGFA
Immunogen:
Human recombinant VEGF 165.
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin)
Clone:
__
Conjugate:
Unconjugated
Gene:
VEGFA
Gene Alias:
angiogenic factor; etID309976.16; eVEGF120; eVEGF164; human VEGF121 homolog; MGC70609; MVCD1; ovine vascular endothelial growth factor; RP1-261G23.1; unnamed protein product; VAS; vascular endothelial growth factor; vascular endothelial growth factor (VEGF) precursor; vascular endothelial growth factor 121 isoform; vascular endothelial growth factor 164; vascular endothelial growth factor 165b; vascular endothelial growth factor 182; vascular endothelial growth factor 182 isoform; vascular endothelial growth factor 188; vascular endothelial growth factor 188 isoform; vascular endothelial growth factor 189; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular endothelial growth factor Aa; Vascular endothelial growth factor A-A; vascular endothelial growth factor isoform 165; vascular permeability factor; Vasculotropin; VEGF; VEGF1; VEGF164; VEGF182; VEGF188; vegfa; VEGF-A; VEGFA165b; vegfaa; VEGF-A-A; VEGFMGC70609; VPF; VPF ant; wu:fj82c06
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
22339, 7422, 83785
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: Caveolin 1
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.05% sodium azide
Gene Accession No.: P41350, Q03135
Gene Symbols: CAV1
Immunogen: Intercellular membrane protein-containing vesicles (containing GLUT4) from rat.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Hamster, Human, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 7C8
Conjugate: Unconjugated
Gene: CAV1
Gene Alias: BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 100753021, 25404, 857
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Caveolin 1
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.05% sodium azide
Gene Accession No.:
P41350, Q03135
Gene Symbols:
CAV1
Immunogen:
Intercellular membrane protein-containing vesicles (containing GLUT4) from rat.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Hamster, Human, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
7C8
Conjugate:
Unconjugated
Gene:
CAV1
Gene Alias:
BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
100753021, 25404, 857
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid