01-950-168

Phospho-IRE1 alpha (Ser724) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-950-168-Each-of-1 In Stock ₹ 44,961.78

01-950-168 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

Phospho-IRE1 alpha (Ser724)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ERN1

Gene Alias

9030414B18Rik; AI225830; C85377; endoplasmic reticulum (ER) to nucleus signalling 1; endoplasmic reticulum to nucleus signaling 1; endoplasmic reticulum to nucleus signalling 1; endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signalling 1; ERN1; FLJ30999; hIRE1p; inositol-requiring 1; inositol-requiring 1 alpha; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; IRE1a antibody; Ire1alpha; Ire1-alpha; Ire1p; IRE1p antibody; MGC163277; MGC163279; protein kinase/endoribonuclease; RGD1559716; Serine/threonine-protein kinase; Serine/threonine-protein kinase/endoribonuclease IRE1; serine/threonine-protein kinase/endoribonuclease IRE1-like

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100357346, 100510978, 102173038, 2081, 498013, 78943

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ChIP Assay, ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, In vitro Assay, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O75460, Q9EQY0

Gene Symbols

ERN1

Immunogen

Synthetic peptide surrounding the phosphorylated serine 724 of the human IRE1 alpha protein.[Swiss-Prot #O75460]

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Drosophila, Goat, Human, Mammalia, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Recommended positive controls: Human pancreas whole tissue Lysate (adult whole tumor), Human epididymis whole tissue lysate (adult whole normal) ERN1 serine/threonine kinase or endoplasmic reticulum to nucleus signaling 1 is the ER to nucleus signaling 1 protein, a human homologue of the yeast Ire1 gene product which possesses intrinsic kinase activity and an endoribonuclease activity and it is important in endoplasmic reticulum-based stress signals
  • ERN1 controls IRE1 proteolysis in mammalian cells
  • ERN1 has a critical function in extraembryonic cells that is essential for fetal viability
  • Specifically, IRE1 acts as the sensor of unfolded proteins in the ER that initiates transmittance of the unfolded protein signal from the ER to the nucleus by splicing XBP1 mRNA converting it into a potent unfolded-protein response transcriptional activator
  • Null mutants are viable, but IRE1 is essential for viability under stress conditions that cause unfolded proteins to accumulate in the ER
  • Depletion of IRE1p through the expression of a dominant negative form of IRE1p has no effect on transfected cells, but cell death via apoptosis occurs under stress conditions that cause unfolded proteins to accumulate in the ER.

Compare Similar Items

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Img

Thermo Scientific

01-950-168

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Antigen:
Phospho-IRE1 alpha (Ser724)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERN1

Gene Alias:
9030414B18Rik; AI225830; C85377; endoplasmic reticulum (ER) to nucleus signalling 1; endoplasmic reticulum to nucleus signaling 1; endoplasmic reticulum to nucleus signalling 1; endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signalling 1; ERN1; FLJ30999; hIRE1p; inositol-requiring 1; inositol-requiring 1 alpha; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; IRE1a antibody; Ire1alpha; Ire1-alpha; Ire1p; IRE1p antibody; MGC163277; MGC163279; protein kinase/endoribonuclease; RGD1559716; Serine/threonine-protein kinase; Serine/threonine-protein kinase/endoribonuclease IRE1; serine/threonine-protein kinase/endoribonuclease IRE1-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100357346, 100510978, 102173038, 2081, 498013, 78943

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ChIP Assay, ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, In vitro Assay, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O75460, Q9EQY0

Gene Symbols:
ERN1

Immunogen:
Synthetic peptide surrounding the phosphorylated serine 724 of the human IRE1 alpha protein.[Swiss-Prot #O75460]

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Drosophila, Goat, Human, Mammalia, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-950-171

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Antigen:
LC3B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP1LC3B2

Gene Alias:
1010001C15Rik; Atg8; ATG8E; ATG8F; ATG8G; Autophagy-related protein LC3 B; autophagy-related ubiquitin-like modifier LC3 B; LC3; LC3 beta; LC3A; LC3B; light chain 3; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; Map1alc3; MAP1BLC3; MAP1LC3; MAP1LC3A; MAP1LC3B; MAP1LC3B2; MAP1LC3B-a; microtubule associated protein 1 light chain 3 beta; microtubule associated protein 1 light chain 3 beta 2; microtubule-associated protein 1 light chain 3; microtubule-associated protein 1 light chain 3 beta; microtubule-associated protein 1 light chain 3 beta 2; microtubule-associated proteins 1A/1B light chain 3; microtubule-associated proteins 1A/1B light chain 3 beta 2; Microtubule-associated proteins 1A/1B light chain 3B; Microtubule-associated proteins 1A/1B light chain 3B-like; Microtubule-associated proteins 1A/1B light chain 3B-like protein; Mpl3; RP11-346K17.1; wu:fb60g11; zbs559; zgc:56434

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100349465, 100359928, 100462754, 100726328, 100769810, 322425, 408001, 427559, 479619, 643246, 64862, 67443, 81631

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Proximity Ligation Assay, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
A6NCE7, O41515, Q62625, Q9CQV6, Q9GZQ8

Gene Symbols:
MAP1LC3B, MAP1LC3B2

Immunogen:
Synthetic peptide between amino acids 1-100 of the human LC3 protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Avian, Bacteria, Bovine, Canine, Chicken, Guinea Pig, Hamster, Human, Invertebrate, Mouse, Non-human Primate, Porcine, Rabbit, Rat, Zebrafish

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-950-174

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Antigen:
PDK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDK1

Gene Alias:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial; B830012B01; D530020C15Rik; isoenzyme 1; kinase isoenzyme 1; lipoamide; mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1; PDH kinase 1; PDHK1; PDK p48; Pdk1; pyruvate dehydrogenase; pyruvate dehydrogenase kinase 1; Pyruvate dehydrogenase kinase isoform 1; pyruvate dehydrogenase kinase, isoenzyme 1; pyruvate dehydrogenase kinase, isozyme 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228026, 5163

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
tris glycine with 0.15M NaCl and 0.05% sodium azide

Gene Accession No.:
Q15118, Q8BFP9

Gene Symbols:
PDK1

Immunogen:
Synthetic peptide between amino acids 300-400 of the human PDK1 protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-950-175

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Antigen:
PHD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Egln1

Gene Alias:
AI503754; C1orf12; C1ORF12 antibody; ECYT3; egl nine homolog 1; egl nine-like protein 1; egl-9 family hypoxia inducible factor 1; egl-9 family hypoxia-inducible factor 1; EGLN 1 EGLN1; EGLN1; HALAH; HIF PH2; HIF prolyl hydroxylase 2; HIF-P4H 2; Hif-p4h-2; HIFPH2; HIF-PH2; HIF-prolyl hydroxylase 2; HPH2; HPH-2; Hypoxia-inducible factor prolyl hydroxylase 2; ORF13; P4H2; Phd2; PHD-2; PNAS-118; PNAS-137; Prolyl Hy; Prolyl hydroxylase domain-containing protein 2; SM20; SM-20; zinc finger MYND domain-containing protein 6; ZMYND6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
112405, 308913, 54583

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P59722, Q91YE3, Q9GZT9

Gene Symbols:
Egln1

Immunogen:
Synthetic peptide between amino acids 300-400 of the mouse HPH-2 protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG