01-950-179

CRYAB Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-950-179-Each-of-1 In Stock ₹ 50,651.52

01-950-179 - Each of 1

₹ 50,651.52

In Stock

Quantity

1

Base Price: ₹ 50,651.52

GST (18%): ₹ 9,117.274

Total Price: ₹ 59,768.794

Antigen

CRYAB

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cryab

Gene Alias

2310001E10Rik; 3526402H21Rik; AACRYA; active transcription factor CREB; alpha B-crystallin; alpha crystallin B; alpha(B)-crystallin; alpha-B-crystallin; Alpha-crystallin B chain; alpha-crystallin B chain-like protein; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CMD1II; CREB; CREB1; CREB-1; Crya2; Crya-2; CRYAB; CryAB antibody; crystallin alpha B; crystallin, alpha 2; crystallin, alpha B; crystallin, alpha polypeptide 2; CTPP2; CTRCT16; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; epididymis secretory protein Li 101; heat shock protein beta-5; heat shock protein CryAB; heat shock protein HspB5; heat-shock 20 kD like-protein; HEL-S-101; HSPB5; HspB5 protein; MFM2; P23; Renal carcinoma antigen NY-REN-27; rosenthal fiber component; transactivator protein; Y protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12955, 1410, 25420

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.08 mg/mL

Formulation

phosphate, tris citrate with 0.1% sodium azide; pH 7-8

Gene Accession No.

P02511, P23927, P23928

Gene Symbols

Cryab

Immunogen

Synthetic peptide between amino acids 70-140 of the human Crystallin AB protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • This Crystallin AB antibody is useful for Western blot analysis, where a band is seen at ∽20 kDa
  • There is also a band of greater intensity at ∽40 kDa that may be an aggregated heteromeric complex
  • CryAB aggregates with homologous proteins, including CryAA and the small heat shock protein HSP28, to form large heteromeric complexes.Suggested positive control: human and mouse skeletal muscle lysate, human skeletal muscle protein, antigen standard for HSPB1 (transient overexpression lysate), mouse skeletal muscle protein
  • Lens proteins consist almost entirely of crystallins (about 95%)
  • Crystallins are also found vertebrate skeletal muscle tissue
  • In the lens, their structural function is to assist in maintaining the proper refractive index of the lens
  • The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma
  • Alpha-crystallin is the largest of the crystallins and is composed of 2 primary gene products-alpha-A and alpha-B
  • There are at least 5 different proteins comprising the beta-crystallins
  • The gamma-crystallins are monomeric, but there are at least 5 gamma crystallins identified in bovine and rat lens
  • Alpha-Crystallin comprises 40% of total lens protein composition
  • In addition to maintaining proper refractive index, it also functions in a chaperone like manner by preventing the formation of aggregates possibly leading to cataract formation
  • It is believed that the phosphorylated states of the alpha-crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintenance
  • Alpha-B crystallin has been linked to Alexander's disease where it accumulates in brain cells of those afflicted.

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-950-179

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Antigen:
CRYAB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cryab

Gene Alias:
2310001E10Rik; 3526402H21Rik; AACRYA; active transcription factor CREB; alpha B-crystallin; alpha crystallin B; alpha(B)-crystallin; alpha-B-crystallin; Alpha-crystallin B chain; alpha-crystallin B chain-like protein; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CMD1II; CREB; CREB1; CREB-1; Crya2; Crya-2; CRYAB; CryAB antibody; crystallin alpha B; crystallin, alpha 2; crystallin, alpha B; crystallin, alpha polypeptide 2; CTPP2; CTRCT16; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; epididymis secretory protein Li 101; heat shock protein beta-5; heat shock protein CryAB; heat shock protein HspB5; heat-shock 20 kD like-protein; HEL-S-101; HSPB5; HspB5 protein; MFM2; P23; Renal carcinoma antigen NY-REN-27; rosenthal fiber component; transactivator protein; Y protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12955, 1410, 25420

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.08 mg/mL

Formulation:
phosphate, tris citrate with 0.1% sodium azide; pH 7-8

Gene Accession No.:
P02511, P23927, P23928

Gene Symbols:
Cryab

Immunogen:
Synthetic peptide between amino acids 70-140 of the human Crystallin AB protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-950-182

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Antigen:
LOX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LOX

Gene Alias:
AI893619; cross-linking enzyme; H-rev142; LOX; Lysyl oxidase; Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts); MGC105112; protein-lysine 6-oxidase; Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form; Ras excision protein; ras recision; rrg; Rrg1; TSC-160

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100525278, 16948, 24914, 4015

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P16636, P28300, P28301, P45845

Gene Symbols:
LOX

Immunogen:
Synthetic peptide between amino acids 200-300 of the human LOX protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-950-184

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Antigen:
LOX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LOX

Gene Alias:
AI893619; cross-linking enzyme; H-rev142; LOX; Lysyl oxidase; Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts); MGC105112; protein-lysine 6-oxidase; Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form; Ras excision protein; ras recision; rrg; Rrg1; TSC-160

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100525278, 16948, 24914, 280841, 4015

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P16636, P28300, P28301, P33072, P45845

Gene Symbols:
LOX

Immunogen:
Cocktail of two synthetic peptides between amino acids 300-350 and amino acids 200-300 of the human LOX protein.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-950-185

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Antigen:
SIRT6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIRT6

Gene Alias:
2810449N18Rik; AI043036; NAD-dependent deacetylase sirtuin-6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; SIR2; SIR2 like 6; Sir2l6; SIR2-like protein 6; sir2-related protein type 6; Sirt6; sirtuin 6; sirtuin type 6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51548

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
phosphate, tris citrate with 0.1% sodium azide; pH 7-8

Gene Accession No.:
Q8N6T7

Gene Symbols:
SIRT6

Immunogen:
Synthetic peptide between amino acids 250-350 of the human SIRT6 protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG