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01-950-251

HP1 alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size	SKU	Availability	Price
Each of 1	01-950-251-Each-of-1	In Stock	₹ 44,705.10

01-950-251 - Each of 1

₹ 44,705.10

In Stock

Quantity

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

HP1 alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cbx5

Gene Alias

2610029O15Rik; antigen p25; C75991; Cbx5; Cbx5 antibody; chromobox 5; chromobox homolog 5; chromobox homolog 5 (HP1 alpha homolog, Drosophila); chromobox protein homolog 5; chromobox-like protein 5; epididymis luminal protein 25; HEL25; heterochromatin protein 1 alpha; heterochromatin protein 1 homolog alpha; heterochromatin protein 1-alpha; HGNC:1555; HP1; HP1 alpha; HP-1 alpha antibody; HP1 alpha homolog; Hp1a; Hp1alpha; HP1-ALPHA; HP1Hs alpha; HP1Hs-alpha; mHP1(alpha)

Host Species

Rabbit

Purification Method

IgG fraction

Regulatory Status

RUO

Gene ID (Entrez)

23468

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Concentration

13 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P45973

Gene Symbols

Cbx5

Immunogen

Synthetic peptide between amino acids 1-100 of the human HP 1 alpha protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Description

This antibody is expected to cross-react with mouse, Arabidopsis suecica, Rye, and Triticum aestivum based on sequence homology
Suggested positive control: antigen standard for CBX5 (transient overexpression lysate), Hela whole cell extract
Heterochromatin protein-1 (HP1) is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing
It has been shown that mammalian methyltransferases that selectively methylate histone H3 on lysine-9 generate a binding site for HP1 proteins, a family of heterochromatic adaptor molecules implicated in both gene silencing and supranucleosomal chromatin structure
High-affinity in vitro recognition of a methylated histone H3 peptide by HP1 requires a functional chromodomain
Thus, the HP1 chromodomain is a specific interaction motif for the methyl epitope on lysine-9 of histone H3
In vivo, heterochromatin association of HP1 proteins is lost in Suv39h double-null primary mouse fibroblasts but is restored after reintroduction of a catalytically active SUV39H1 HMTase.

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Thermo Scientific

01-950-251

Antigen:

HP1 alpha

Classification:

Polyclonal

Conjugate:

Unconjugated

Gene:

Cbx5

Gene Alias:

2610029O15Rik; antigen p25; C75991; Cbx5; Cbx5 antibody; chromobox 5; chromobox homolog 5; chromobox homolog 5 (HP1 alpha homolog, Drosophila); chromobox protein homolog 5; chromobox-like protein 5; epididymis luminal protein 25; HEL25; heterochromatin protein 1 alpha; heterochromatin protein 1 homolog alpha; heterochromatin protein 1-alpha; HGNC:1555; HP1; HP1 alpha; HP-1 alpha antibody; HP1 alpha homolog; Hp1a; Hp1alpha; HP1-ALPHA; HP1Hs alpha; HP1Hs-alpha; mHP1(alpha)

Host Species:

Rabbit

Purification Method:

IgG fraction

Regulatory Status:

RUO

Gene ID (Entrez):

23468

Content And Storage:

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:

Liquid

Applications:

Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:

13 mg/mL

Formulation:

PBS with 0.02% sodium azide

Gene Accession No.:

P45973

Gene Symbols:

Cbx5

Immunogen:

Synthetic peptide between amino acids 1-100 of the human HP 1 alpha protein.

Quantity:

100 μL

Primary or Secondary:

Primary

Target Species:

Human

Product Type:

Antibody

Isotype:

IgG

W.A. Hammond

01-952

Antigen:

Classification:

Conjugate:

Gene:

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Regulatory Status:

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Product Type:

Mini-dehumidifier

Isotype:

__

Invitrogen

01-960-1

Antigen:

Normal Rat Serum

Classification:

Conjugate:

Unconjugated

Gene:

Gene Alias:

Host Species:

Rat

Purification Method:

Regulatory Status:

RUO

Gene ID (Entrez):

Content And Storage:

Form:

Lyophilized

Applications:

Concentration:

Formulation:

whole serum with 0.1% sodium azide

Gene Accession No.:

Gene Symbols:

Immunogen:

Rat immunoglobins

Quantity:

5 mL

Primary or Secondary:

Target Species:

None

Product Type:

Isotype:

Ig Mix

Krackeler Scientific

01001516N

Antigen:

Classification:

Conjugate:

Gene:

Gene Alias:

Host Species:

Purification Method:

Regulatory Status:

Gene ID (Entrez):

Content And Storage:

Form:

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Gene Symbols:

Immunogen:

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Product Type:

Isotype:

HP1 alpha Polyclonal Antibody, Invitrogen™

Select a Size

Select a Size

Properties

Antigen

Classification

Conjugate

Gene

Gene Alias

Host Species

Purification Method

Regulatory Status

Gene ID (Entrez)

Content And Storage

Form

Applications

Concentration

Formulation

Gene Accession No.

Gene Symbols

Immunogen

Quantity

Primary or Secondary

Target Species

Product Type

Isotype

Related Products

Thermo Scientific

Thermo Scientific

Thermo Scientific

Thermo Scientific

Thermo Scientific

Thermo Scientific

Thermo Scientific

Thermo Scientific

Description

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Thermo Scientific

W.A. Hammond

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