05-172-AF488
MilliporeSigma™ anti-IGF-I Alexa Fluor 488, Clone: Sm1.2,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 05-172-AF488-Each-of-1 | In Stock | ₹ 42,968.31 |
05-172-AF488 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,968.31
GST (18%): ₹ 7,734.296
Total Price: ₹ 50,702.606
Antigen
IGF-I
Classification
Monoclonal
Conjugate
Alexa Fluor 488
Gene Accession No.
P05019
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
IGF-I (Russel, W.E., (1984). Proc. Natl. Acad. Sci. U. S. A. 81(8):2389-2392). 40% cross reactivity to IGF-II (Van Wyk, J.J., and Bruton, E.T. (1997). Endocrinology. 138(10):4521-4522).
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG1 κ
Applications
Immunocytochemistry
Clone
Sm1.2
Formulation
Purified mouse antibody conjugate in PBS with 15mg/mL BSA and 0.1 % sodium azide.
Gene Symbols
IGF1, IBP1
Immunogen
Highly purified human plasma insulin-like growth factor I (IGF-I; Somatomedin C; Sm-C) conjugated to mouse albumin (Van Wyk, J.J., and Bruton, E.T. (1997). Endocrinology. 138(10):4521-4522). Action of somatomedins on cell growth: Effect of selective neutralisation of somatomedin C (IGF-I) with a Monoclonal. In: Raiti, S., Tolman, and R.A. (eds.), Human Growth Hormone. pp. 585–599. Plenum Publishing Corp., New York, NY).
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_000609
Target Species
Chicken, Fish, Human, Mouse, Rat
Form
Purified
Description
- Specifically detects IGF-I Clone: Sm1.2 in Chicken, Fish, Human, Mouse, Rat samples, and it is validated for Immunocytochemistry Insulin-like growth factor I (UniProt P05019; also known as IGF-I, Somatomedin-C) is encoded by the IGF1 (also known as IGFI, MGF) gene (Gene ID 3479) in human
- Human insulin-like growth factor-I (IGF-I) is a single chain 70 amino acid polypeptide that shares structural homology with insulin and human IGF-II
- IGF-I plays a critical role in growth, differentiation and development via autocrine, paracrine and endocrine mechanisms
- It is a mitogen and also has effects on cell migration and differentiation
- IGF-I is a regulator of metabolism and is also implicated in the pathophysiology of cancer, diabetes and obesity
- Upon binding the tetrameric (alpha:beta)2 IGF-I receptor, the receptor alpha chains induce the tyrosine autophosphorylation of the beta chains, which in turn trigger cell type-specific downstream signaling cascade of events.
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Antigen: IGF-I
Classification: Monoclonal
Conjugate: Alexa Fluor 488
Gene Accession No.: P05019
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: IGF-I (Russel, W.E., (1984). Proc. Natl. Acad. Sci. U. S. A. 81(8):2389-2392). 40% cross reactivity to IGF-II (Van Wyk, J.J., and Bruton, E.T. (1997). Endocrinology. 138(10):4521-4522).
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Immunocytochemistry
Clone: Sm1.2
Formulation: Purified mouse antibody conjugate in PBS with 15mg/mL BSA and 0.1 % sodium azide.
Gene Symbols: IGF1, IBP1
Immunogen: Highly purified human plasma insulin-like growth factor I (IGF-I; Somatomedin C; Sm-C) conjugated to mouse albumin (Van Wyk, J.J., and Bruton, E.T. (1997). Endocrinology. 138(10):4521-4522). Action of somatomedins on cell growth: Effect of selective neutralisation of somatomedin C (IGF-I) with a Monoclonal. In: Raiti, S., Tolman, and R.A. (eds.), Human Growth Hormone. pp. 585–599. Plenum Publishing Corp., New York, NY).
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_000609
Target Species: Chicken, Fish, Human, Mouse, Rat
Form: Purified
Antigen:
IGF-I
Classification:
Monoclonal
Conjugate:
Alexa Fluor 488
Gene Accession No.:
P05019
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
IGF-I (Russel, W.E., (1984). Proc. Natl. Acad. Sci. U. S. A. 81(8):2389-2392). 40% cross reactivity to IGF-II (Van Wyk, J.J., and Bruton, E.T. (1997). Endocrinology. 138(10):4521-4522).
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Immunocytochemistry
Clone:
Sm1.2
Formulation:
Purified mouse antibody conjugate in PBS with 15mg/mL BSA and 0.1 % sodium azide.
Gene Symbols:
IGF1, IBP1
Immunogen:
Highly purified human plasma insulin-like growth factor I (IGF-I; Somatomedin C; Sm-C) conjugated to mouse albumin (Van Wyk, J.J., and Bruton, E.T. (1997). Endocrinology. 138(10):4521-4522). Action of somatomedins on cell growth: Effect of selective neutralisation of somatomedin C (IGF-I) with a Monoclonal. In: Raiti, S., Tolman, and R.A. (eds.), Human Growth Hormone. pp. 585–599. Plenum Publishing Corp., New York, NY).
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000609
Target Species:
Chicken, Fish, Human, Mouse, Rat
Form:
Purified
Antigen: IGF-I
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_000609
Host Species: Mouse
Purification Method: Protein G purfied
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C for up to 12 months.
Isotype: IgG1 κ
Applications: Immunohistochemistry, Immunoprecipitation, Neutralization, Western Blot
Clone: Sm1.2
Formulation: Purified mouse IgG1κ lyophilized powder, lyophilized from 105μL of 0.1MTris-glycine, pH 7.4, 0.15MNaCl, 0.1mM EDTA.
Gene Symbols: IGF1, IBP1, IGFI, IGF-IA, MGF, IGF-IB
Immunogen: Human insulin-like growth factor I (IGF-I) purified from human plasma. (van Wyk, J.J., 1986).
Quantity: 200 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Avian, Chicken, Human, Mouse, Rat
Form: Purified
Antigen:
IGF-I
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_000609
Host Species:
Mouse
Purification Method:
Protein G purfied
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C for up to 12 months.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Immunoprecipitation, Neutralization, Western Blot
Clone:
Sm1.2
Formulation:
Purified mouse IgG1κ lyophilized powder, lyophilized from 105μL of 0.1MTris-glycine, pH 7.4, 0.15MNaCl, 0.1mM EDTA.
Gene Symbols:
IGF1, IBP1, IGFI, IGF-IA, MGF, IGF-IB
Immunogen:
Human insulin-like growth factor I (IGF-I) purified from human plasma. (van Wyk, J.J., 1986).
Quantity:
200 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Avian, Chicken, Human, Mouse, Rat
Form:
Purified
Antigen: Myb
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NM_005375.2
Host Species: Mouse
Purification Method: Ammonium sulfate precipitation, gel filtration, and ion-exchange chromatography.
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C in undiluted aliquots for up to 12 months.
Isotype: IgG2a κ
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: 1-1
Formulation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-glycine, pH 7.4, 0.15MNaCl and 0.05% sodium azide. Frozen solution.
Gene Symbols: MYB, C-myb, c-myb13A_CDS, c-myb8B_CDS, c-myb_CDS, v-myb, c-myb14A_CDS, Cmyb, c-myb, efg, c-myb10A_CDS
Immunogen: Recombinant murine Myb purified by SDS-PAGE (Nicot, C., 2001) Clone 1-1.
Quantity: 250 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Mouse
Form: Purified
Antigen:
Myb
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NM_005375.2
Host Species:
Mouse
Purification Method:
Ammonium sulfate precipitation, gel filtration, and ion-exchange chromatography.
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C in undiluted aliquots for up to 12 months.
Isotype:
IgG2a κ
Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
1-1
Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-glycine, pH 7.4, 0.15MNaCl and 0.05% sodium azide. Frozen solution.
Gene Symbols:
MYB, C-myb, c-myb13A_CDS, c-myb8B_CDS, c-myb_CDS, v-myb, c-myb14A_CDS, Cmyb, c-myb, efg, c-myb10A_CDS
Immunogen:
Recombinant murine Myb purified by SDS-PAGE (Nicot, C., 2001) Clone 1-1.
Quantity:
250 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Mouse
Form:
Purified
Antigen: FAK
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NM_005607.3; NM_153831.2
Host Species: Mouse
Purification Method: Protein G purfied
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C in undiluted aliquots for up to 24 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG1
Applications: Immunocytochemistry, Immunoprecipitation
Clone: 2A7
Formulation: Protein G Purified immunoglobulin in Protein G Purified immunoglobulin in Purified immunoglobulin in 10mM PBS, pH 7.4 containing no preservatives.
Gene Symbols: PTK2, pp125FAK, FAK, FADK, FAK1
Immunogen: Mixture of affinity-purified tyrosine phosphoproteins from chick embryo fibroblasts expressing p125FAK.
Quantity: 200 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Avian, Human, Mouse, Rat
Form: Purified
Antigen:
FAK
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NM_005607.3; NM_153831.2
Host Species:
Mouse
Purification Method:
Protein G purfied
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C in undiluted aliquots for up to 24 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunoprecipitation
Clone:
2A7
Formulation:
Protein G Purified immunoglobulin in Protein G Purified immunoglobulin in Purified immunoglobulin in 10mM PBS, pH 7.4 containing no preservatives.
Gene Symbols:
PTK2, pp125FAK, FAK, FADK, FAK1
Immunogen:
Mixture of affinity-purified tyrosine phosphoproteins from chick embryo fibroblasts expressing p125FAK.
Quantity:
200 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Avian, Human, Mouse, Rat
Form:
Purified