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05591AF647

MilliporeSigma™ Akt/PKB, PH Domain, Mouse, Alexa Fluor 647, Clone: SKB1,

Manufacturer: MilliporeSigma™

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Pack Size	SKU	Availability	Price
Each of 1	05591AF647-Each-of-1	In Stock	₹ 47,562.80

05591AF647 - Each of 1

₹ 47,562.80

In Stock

Quantity

Base Price: ₹ 47,562.80

GST (18%): ₹ 8,561.304

Total Price: ₹ 56,124.104

Antigen

Akt/PKB, PH Domain

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse monoclonal IgG antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % Sodium Azide.

Gene Accession No.

P31749

Immunogen

GST-fusion protein corresponding to residues 1-149 of human Akt1.

Quantity

100 μL

Research Discipline

Apoptosis & Cancer

Gene ID (Entrez)

NM_005163

Target Species

Human

Form

Purified

Applications

Immunocytochemistry

Clone

SKB1

Conjugate

Alexa Fluor 647

Gene

AKT1, PKB, RAC

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone SKB1 recognizes Akt1 and Akt2, but not Akt3, GST fusion proteins at 100 ng by immunoblotting analysis using the unconjugated antibody (Mfr. No. 05-591).

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG

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Description

RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1; UniProt P31749; also known as PKB, PKB alpha, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha) is encoded by the AKT1 (also known as PKB, RAC) gene (Gene ID 207) in human
AKTs (protein kinase Bs) are serine/threonine kinases that play an important role in signal transduction pathways involved in cell proliferation, apoptosis, angiogenesis, and diabetes
There exit three types of AKTs (α, β, γ or AKT 1, 2, 3) sharing a high degree of homology, but differing slightly in the localization of their regulatory phosphorylation sites
AKT α is the predominant isoform in most tissues, whereas the highest expression of AKT β is observed in the insulin-responsive tissues, and AKT γ is abundant in brain tissue
Each AKT type is composed of three functionally distinct regions, including an N-terminal pleckstrin homology (PH) domain that provides a lipid-binding module to direct Akt to PIP2 and PIP3, a central catalytic domain, and a C-terminal hydrophobic motif.

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05591AF647

Antigen:

Akt/PKB, PH Domain

Classification:

Monoclonal

Concentration:

Please refer to lot specific datasheet.

Formulation:

Purified mouse monoclonal IgG antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % Sodium Azide.

Gene Accession No.:

P31749

Immunogen:

GST-fusion protein corresponding to residues 1-149 of human Akt1.

Quantity:

100 μL

Research Discipline:

Apoptosis & Cancer

Gene ID (Entrez):

NM_005163

Target Species:

Human

Form:

Purified

Applications:

Immunocytochemistry

Clone:

SKB1

Conjugate:

Alexa Fluor 647

Gene:

AKT1, PKB, RAC

Host Species:

Mouse

Purification Method:

Protein G Purified

Regulatory Status:

RUO

Primary or Secondary:

Primary

Test Specificity:

Clone SKB1 recognizes Akt1 and Akt2, but not Akt3, GST fusion proteins at 100 ng by immunoblotting analysis using the unconjugated antibody (Mfr. No. 05-591).

Content And Storage:

Stable for 1 year at 2°-8°C from date of receipt.

Isotype:

IgG

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MilliporeSigma™ Akt/PKB, PH Domain, Mouse, Alexa Fluor 647, Clone: SKB1,

Select a Size

Select a Size

Properties

Antigen

Classification

Concentration

Formulation

Gene Accession No.

Immunogen

Quantity

Research Discipline

Gene ID (Entrez)

Target Species

Form

Applications

Clone

Conjugate

Gene

Host Species

Purification Method

Regulatory Status

Primary or Secondary

Test Specificity

Content And Storage

Isotype

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