06-429-IMI
MilliporeSigma™ Chicken anti-IGF-IRα subunit, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 06-429-IMI-Each-of-1 | In Stock | ₹ 40,197.80 |
06-429-IMI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,197.80
GST (18%): ₹ 7,235.604
Total Price: ₹ 47,433.404
Antigen
IGF-IRα subunit
Classification
Polyclonal
Gene Accession No.
P08069
Host Species
Chicken
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Isotype
IgY
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Formulation
Purified chicken polyclonal IgY antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
IGF1R
Immunogen
KLH-conjugated synthetic peptide [C-KYADGTIDIEEVTENPKT] corresponding to amino acid residues 672-689 of human IGF-IR alpha chain.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_000866
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Description
- Specifically detects IGF-IRα subunit in Human samples, and it is validated for Immunocytochemistry, Immunoprecipitation, Western Blotting Insulin-like growth factor 1 receptor (EC:2.7.10.1; UniProt P08069; also known as CD221, IGF-I receptor, Insulin-like growth factor I receptor) is encoded by the IGF1R (also known as CD221, IGFIR, IGFR, JTK13) gene (Gene ID 3480) in human
- The insulin-like growth factor 1 (IGF-1) receptor has tyrosine kinase that is activated by IGF-1 and IGF-2 binding
- IGF-1 receptor is initially produced as a precursor protein with an aignal peptide sequence (aa 1-30)
- Post-translational cleavages produce one extracellular alpha (aa 31-736) chain and one transmembrane beta chain (aa 741 – 1367) linked together by a disulfide bond
- Two sets of alpha-beta dimers then form the functional tetrameric receptor complex via a disulfide linkage between their alpha chain
- Upon ligand binding, the alpha chains induce the tyrosine auto-phosphorylation of the beta chains, which in turn triggers cell type-specific downstream signaling cascade of events.
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Antigen: IGF-IRα subunit
Classification: Polyclonal
Gene Accession No.: P08069
Host Species: Chicken
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgY
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Formulation: Purified chicken polyclonal IgY antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: IGF1R
Immunogen: KLH-conjugated synthetic peptide [C-KYADGTIDIEEVTENPKT] corresponding to amino acid residues 672-689 of human IGF-IR alpha chain.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_000866
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Antigen:
IGF-IRα subunit
Classification:
Polyclonal
Gene Accession No.:
P08069
Host Species:
Chicken
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgY
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Formulation:
Purified chicken polyclonal IgY antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
IGF1R
Immunogen:
KLH-conjugated synthetic peptide [C-KYADGTIDIEEVTENPKT] corresponding to amino acid residues 672-689 of human IGF-IR alpha chain.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000866
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
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