07-449-AF488
MilliporeSigma™ anti-trimethyl-Histone H3 (Lys27), Alexa Fluor 488, Polyclonal
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 07-449-AF488-Each-of-1 | In Stock | ₹ 59,262.28 |
07-449-AF488 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 59,262.28
GST (18%): ₹ 10,667.21
Total Price: ₹ 69,929.49
Antigen
trimethyl-Histone H3 (Lys27)
Classification
Polyclonal
Formulation
Purified rabbit antibody conjugate in PBS with 15mg/mL BSA and 0.1% sodium azide.
Gene Symbols
HIST3H3, H3FT
Immunogen
KLH-conjugated, synthetic 2X-branched peptide containing the sequence …AR(Kme3)SAP… in which Kme3 corresponds to trimethyl-lysine at residue 27 of human histone H3.
Quantity
100 μL
Research Discipline
Epigenetics, Nuclear Function
Gene ID (Entrez)
NM_003493
Target Species
Human, Mouse, Rat
Form
Purified
Applications
Immunohistochemistry
Conjugate
Alexa Fluor 488
Gene Accession No.
Q16695
Host Species
Rabbit
Purification Method
Protein A purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
H3K27me3 specificity of the unconjugated antibody has been confirmed using the Absurance™ Histone H3 Antibody Specificity Array and the Absurance™ Histone H2A, H2B, H4 Antibody Specificity Array.
Content And Storage
2°C to 8°C for one year
Isotype
IgG
Description
- Specifically detects trimethyl-Histone H3 (Lys27) Clone: in Human, Mouse, Rat samples, and it is validated for Immunohistochemistry Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells
- Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the'beads on a string' structure
- The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes
- These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine
- Histone H3 variants (H3.1, H3.2 and H3.3) have been implicated in the epigenetic memory of cellular state
- Genome-wide patterns of H3 are dependent on amino acid sequence and change with cellular differentiation at developmentally regulated loci.
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Antigen: trimethyl-Histone H3 (Lys27)
Classification: Polyclonal
Formulation: Purified rabbit antibody conjugate in PBS with 15mg/mL BSA and 0.1% sodium azide.
Gene Symbols: HIST3H3, H3FT
Immunogen: KLH-conjugated, synthetic 2X-branched peptide containing the sequence …AR(Kme3)SAP… in which Kme3 corresponds to trimethyl-lysine at residue 27 of human histone H3.
Quantity: 100 μL
Research Discipline: Epigenetics, Nuclear Function
Gene ID (Entrez): NM_003493
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Immunohistochemistry
Conjugate: Alexa Fluor 488
Gene Accession No.: Q16695
Host Species: Rabbit
Purification Method: Protein A purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: H3K27me3 specificity of the unconjugated antibody has been confirmed using the Absurance™ Histone H3 Antibody Specificity Array and the Absurance™ Histone H2A, H2B, H4 Antibody Specificity Array.
Content And Storage: 2°C to 8°C for one year
Isotype: IgG
Antigen:
trimethyl-Histone H3 (Lys27)
Classification:
Polyclonal
Formulation:
Purified rabbit antibody conjugate in PBS with 15mg/mL BSA and 0.1% sodium azide.
Gene Symbols:
HIST3H3, H3FT
Immunogen:
KLH-conjugated, synthetic 2X-branched peptide containing the sequence …AR(Kme3)SAP… in which Kme3 corresponds to trimethyl-lysine at residue 27 of human histone H3.
Quantity:
100 μL
Research Discipline:
Epigenetics, Nuclear Function
Gene ID (Entrez):
NM_003493
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Immunohistochemistry
Conjugate:
Alexa Fluor 488
Gene Accession No.:
Q16695
Host Species:
Rabbit
Purification Method:
Protein A purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
H3K27me3 specificity of the unconjugated antibody has been confirmed using the Absurance™ Histone H3 Antibody Specificity Array and the Absurance™ Histone H2A, H2B, H4 Antibody Specificity Array.
Content And Storage:
2°C to 8°C for one year
Isotype:
IgG
Antigen: trimethyl Histone H3 (Lys27)
Classification: Polyclonal
Formulation: Purified rabbit IgG in PBS containing 15mg/mL BSA and 0.1% Sodium Azide.
Gene Symbols: HIST3H3; H3FT
Immunogen: Branch peptide corresponding to trimethyl-Histone H3 (Lys27).
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): NM_003493
Target Species: Human
Form: Purified
Applications: Immunocytochemistry
Conjugate: Alexa Fluor 555
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Protein A purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Isotype: __
Antigen:
trimethyl Histone H3 (Lys27)
Classification:
Polyclonal
Formulation:
Purified rabbit IgG in PBS containing 15mg/mL BSA and 0.1% Sodium Azide.
Gene Symbols:
HIST3H3; H3FT
Immunogen:
Branch peptide corresponding to trimethyl-Histone H3 (Lys27).
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
NM_003493
Target Species:
Human
Form:
Purified
Applications:
Immunocytochemistry
Conjugate:
Alexa Fluor 555
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Protein A purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Isotype:
__
Antigen: dimethyl-Histone H3 (Lys27)
Classification: Polyclonal
Formulation: Affinity purified IgG in 0.1M Tris-Glycine (pH7.4), 150mM NaCl with 0.05% NaN3.
Gene Symbols: HIST3H3; H3FT; H3/t; H3t; MGC126888; H3/g; H3.4; H3T; MGC126886
Immunogen: KLH-conjugated, synthetic 2X-branched peptide containing the sequence ...ARme2KSA... in whichme2K corresponds to dimethyl-lysine at residue 27 of human histone H3
Quantity: 200 μg
Research Discipline: __
Gene ID (Entrez): NM_003493
Target Species: Human
Form: __
Applications: Multiplex, Dot Blot, Immunoassay, Inhibition Assays, Western Blot
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for up to 24 months
Isotype: IgG
Antigen:
dimethyl-Histone H3 (Lys27)
Classification:
Polyclonal
Formulation:
Affinity purified IgG in 0.1M Tris-Glycine (pH7.4), 150mM NaCl with 0.05% NaN3.
Gene Symbols:
HIST3H3; H3FT; H3/t; H3t; MGC126888; H3/g; H3.4; H3T; MGC126886
Immunogen:
KLH-conjugated, synthetic 2X-branched peptide containing the sequence ...ARme2KSA... in whichme2K corresponds to dimethyl-lysine at residue 27 of human histone H3
Quantity:
200 μg
Research Discipline:
__
Gene ID (Entrez):
NM_003493
Target Species:
Human
Form:
__
Applications:
Multiplex, Dot Blot, Immunoassay, Inhibition Assays, Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for up to 24 months
Isotype:
IgG
Antigen: B-Raf
Classification: Polyclonal
Formulation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl,0.05% sodium azide before the addition of glycerol to 30%
Gene Symbols: BRAF; B-raf-1; BRAF1; MGC126806; B-Raf; p94; MGC138284; RAFB1
Immunogen: synthetic peptide corresponding to amino acids 754-765 of human B-Raf
Quantity: 200 μg
Research Discipline: __
Gene ID (Entrez): NM_004333
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Protein A chromatography
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C for 24 months
Isotype: IgG
Antigen:
B-Raf
Classification:
Polyclonal
Formulation:
0.1M Tris-glycine, pH 7.4, 0.15M NaCl,0.05% sodium azide before the addition of glycerol to 30%
Gene Symbols:
BRAF; B-raf-1; BRAF1; MGC126806; B-Raf; p94; MGC138284; RAFB1
Immunogen:
synthetic peptide corresponding to amino acids 754-765 of human B-Raf
Quantity:
200 μg
Research Discipline:
__
Gene ID (Entrez):
NM_004333
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Protein A chromatography
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C for 24 months
Isotype:
IgG