07-748-AF555

MilliporeSigma™ monomethyl Histone H4 (Lys20), Rabbit, Alexa Fluor 555, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 07-748-AF555-Each-of-1 In Stock ₹ 48,229.10

07-748-AF555 - Each of 1

₹ 48,229.10

In Stock

Quantity

1

Base Price: ₹ 48,229.10

GST (18%): ₹ 8,681.238

Total Price: ₹ 56,910.338

Antigen

monomethyl Histone H4 (Lys20)

Classification

Polyclonal

Conjugate

Alexa Fluor 555

Gene

HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4

Host Species

Rabbit

Purification Method

Protein A Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This polyclonal antibody detects histone H4 with monomethylated Lys20 (H4K20me1).

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Applications

Immunocytochemistry

Concentration

Please refer to lot specific datasheet.

Formulation

Purified rabbit polyclonal antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % Sodium Azide.

Gene Accession No.

P62805

Immunogen

KLH-conjugated, branched synthetic peptide corresponding to amino acids 15-25 (AKRHR[Kme]VLRDN) of human Histone H4 with monomethylated Lys20.

Quantity

100 μL

Research Discipline

Epigenetics & Nuclear Function

Gene ID (Entrez)

NM_001034077.4

Target Species

Human

Form

Purified

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Description

  • Histone H4 (UniProt P62805; also known as H4 histone family member A, Histone 1 H4a) is encoded by the HIST1H4A (also known as H4/A, H4FA) gene (Gene ID 8359) in human
  • Histone H4 is one of the main histone proteins that contribut to the chromatin structure in both prokaryotic and eukaryotic cells
  • Consecutive methylation of the histone H4 Lys20 (H4K20) is dependent on nucleosome age, and different H4K20 methylation levels are found at distinct nuclear loci
  • H4K20 monomethylation (H4K20me1) is a repressive mark of transcribed genes, whereas H4K20 trimethylation (H4K20me3) is found in repetitive elements in the human genome
  • More than 80% of H4K20 is dimethylated in human cells
  • At least three different methyltransferases (KMTs) have been identified that can catalyze H4K20 methylation, while only lysine demethylases (KDMs) for H4K20me1, but not for H4K20me2 or H4K20me3, have been discovered
  • The monomethyltransferase gene Setd8 knockout in mouse and in Drosophila is lethal due to defects in cell cycle progression.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

07-748-AF555

--


Antigen:
monomethyl Histone H4 (Lys20)

Classification:
Polyclonal

Conjugate:
Alexa Fluor 555

Gene:
HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4

Host Species:
Rabbit

Purification Method:
Protein A Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antibody detects histone H4 with monomethylated Lys20 (H4K20me1).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Immunocytochemistry

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % Sodium Azide.

Gene Accession No.:
P62805

Immunogen:
KLH-conjugated, branched synthetic peptide corresponding to amino acids 15-25 (AKRHR[Kme]VLRDN) of human Histone H4 with monomethylated Lys20.

Quantity:
100 μL

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
NM_001034077.4

Target Species:
Human

Form:
Purified

Img

MilliporeSigma

07-748-MI

--


Antigen:
monomethyl-Histone H4 (Lys20)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Protein A purfied

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
−20°C for 24 months

Applications:
Multiplex, Immunoassay, Western Blot

Concentration:
__

Formulation:
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide and 30% glycerol.

Gene Accession No.:
__

Immunogen:
KLH-conjugated, branched synthetic peptide corresponding to amino acids 15-25 (AKRHR[me1K]VLRDN) of human Histone H4

Quantity:
200 μg

Research Discipline:
__

Gene ID (Entrez):
NM_001034077.4

Target Species:
Human

Form:
Purified

Img

MilliporeSigma

07-753-MI

--


Antigen:
RIAP-3 (XIAP)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Protein A purfied

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
−20°C for 24 months

Applications:
Western Blot

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Immunogen:
GST fusion protein corresponding to full-length rat inhibitor of apoptosis 3 (RIAP-3), also know as X-linked inhibitor of apoptosis (XIAP)

Quantity:
200 μg

Research Discipline:
__

Gene ID (Entrez):
NM_001167.2

Target Species:
Human, Rat

Form:
Purified

Img

MilliporeSigma

07-758-MI

--


Antigen:
phospho-Flt-1 (Tyr1213)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2-8°C for 12 months Avoid repeated freeze/thaw cycles.

Applications:
Western Blot

Concentration:
__

Formulation:
Immunoaffinity purified rabbit IgG in 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide.

Gene Accession No.:
__

Immunogen:
KLH-conjugated, synthetic peptide containing the sequence (...VR[pY]VN...) in which [pY] corresponds to phospho-tyrosine at residue 1213 of human Flt-1. The immunizing sequence is identical in marmoset, has 14/15 identical amino acids in rat, goat, sheep

Quantity:
100 μL

Research Discipline:
__

Gene ID (Entrez):
NM_002019.2

Target Species:
Bovine, Goat, Human, Mouse, Rat, Sheep

Form:
__