11-589-181

CD249 (BP-1) Monoclonal Antibody (6C3), FITC, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 11-589-181-Each-of-1 In Stock ₹ 9,968.00

11-589-181 - Each of 1

₹ 9,968.00

In Stock

Quantity

1

Base Price: ₹ 9,968.00

GST (18%): ₹ 1,794.24

Total Price: ₹ 11,762.24

Antigen

CD249 (BP-1)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P16406

Gene Symbols

Enpep

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13809

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

6C3

Conjugate

FITC

Gene

Enpep

Gene Alias

6030431M22Rik; Aminopeptidase A; aminopeptidase-A; APA; AP-A; BP1; Bp-1/6C3; BP-1/6C3 antigen; CD249; differentiation antigen gp160; EAP; ENPEP; Glutamyl aminopeptidase; glutamyl aminopeptidase (aminopeptidase A); gp160; Ly51; Ly-51

Host Species

Rat

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • Description: The 6C3 monoclonal antibody reacts with mouse BP-1, also known as Ly-51 and 6C3 antigen
  • BP-1 is a 140 kDa type II transmembrane protein that is present on the surface as a disulfide-linked homodimer
  • This molecule is an enzyme with aminopeptidase A (APA) activity and is expressed by bone marrow stromal cells, thymic cortical epithelial cells and at early stages of mouse B cell development, on pre-B cells
  • The low level of BP-1 expression on pre-B cells can be upregulated in the presence of IL-7
  • Applications Reported: The 6C3 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: The 6C3 antibody has been tested by flow cytometric analysis of mouse bone marrow cells
  • This can be used at less than or equal to 1 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • CD249 appears to have a role in the catabolic pathway of the renin-angiotensin system
  • Probably plays a role in regulating growth and differentiation of early B-lineage cells.