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12-088-282

CD88 (C5aR1) Monoclonal Antibody (20/70), PE, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 12-088-282-Each-of-1 In Stock ₹ 24,897.96

12-088-282 - Each of 1

₹ 24,897.96

In Stock

Quantity

1

Base Price: ₹ 24,897.96

GST (18%): ₹ 4,481.633

Total Price: ₹ 29,379.593

Antigen

CD88 (C5aR1)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.

P30993

Gene Symbols

C5AR1

Immunogen

RBL-2H3 transfected cells expressing murine C5aR

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

20/70

Conjugate

PE

Gene

C5AR1

Gene Alias

anaphylatoxin C5a receptor, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin receptor, C5a ligand, C5a Receptor, C5AR, C5a-R, C5AR1, C5r1, Cd88, CD88 antigen, complement C5a receptor, complement C5a receptor 1, complement component 5 receptor 1, complement component 5, receptor 1, complement component 5a receptor 1, D7Msu1

Host Species

Rat

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12273

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Description

  • Description: This 20/70 monoclonal antibody recognizes mouse CD88 also known as C5aR1
  • CD88 is a complement receptor widely expressed on cells of the myeloid lineage
  • Clone 20/70 has been reported to block the binding of C5a to murine CD88
  • Applications Reported: This 20/70 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 20/70 antibody has been tested by flow cytometric analysis of mouse bone marrow cells
  • This may be used at less than or equal to 0.5 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known
  • C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract
  • CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a
  • Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production
  • CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex
  • Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.

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Antigen:
CD88 (C5aR1)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
P30993
Gene Symbols:
C5AR1
Immunogen:
RBL-2H3 transfected cells expressing murine C5aR
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
20/70
Conjugate:
PE
Gene:
C5AR1
Gene Alias:
anaphylatoxin C5a receptor, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin receptor, C5a ligand, C5a Receptor, C5AR, C5a-R, C5AR1, C5r1, Cd88, CD88 antigen, complement C5a receptor, complement C5a receptor 1, complement component 5 receptor 1, complement component 5, receptor 1, complement component 5a receptor 1, D7Msu1
Host Species:
Rat
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12273
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid

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CD7; CD90; CDw90; FLJ33325; membrane glycoprotein; T25; Thy 1.2; THY1; Thy-1; Thy-1 antigen; Thy-1 cell surface antigen; thy-1 glycoprotein; thy-1 membrane glycoprotein; Thy-1 protein; Thy-1 T-cell antigen; Thy1.1; Thy1.2; Thy-1.2; thymus cell antigen 1, theta; Thymus cell surface antigen
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