12-365-942

CD365 (TIM1) Monoclonal Antibody (1D12-TIM1), PE, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 12-365-942-Each-of-1 In Stock ₹ 31,828.32

12-365-942 - Each of 1

₹ 31,828.32

In Stock

Quantity

1

Base Price: ₹ 31,828.32

GST (18%): ₹ 5,729.098

Total Price: ₹ 37,557.418

Antigen

CD365 (TIM1)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

Q96D42

Gene Symbols

Havcr1

Immunogen

IgV domain of human CD365

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

1D12-TIM1

Conjugate

PE

Gene

Havcr1

Gene Alias

AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26762

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Description

  • Description: This 1D12-TIM1 monoclonal antibody recognizes human CD365 also known as Tim-1, Kim-1 or Havcr1
  • This antibody was generated using the immunoglobulin V domain of the extracellular part of the CD365 receptor, and is predicted to recognize all three haplotypes of human CD365
  • Clone 1D12-TIM1 has been shown to block entry of HCV virus into human hepatoma Huh7.5 cells in a dose dependent manner
  • It has been also shown to block the uptake of apoptotic cells by CD365-expressing 769-P cells
  • Applications Reported: This 1D12-TIM1 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 1D12-TIM1 antibody has been pre-diluted and tested by flow cytometric analysis of A549 cells
  • This may be used at 5 μL (0.125 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein that consists of extracellular N-terminal immunoglobulin V-like domain and a mucin domain, and a short cytoplasmic tail
  • The endogenous ligand for CD365 is Tim-4
  • In addition, CD365 is known to be a cellular receptor or co-receptor for a number of viruses including hepatitis A and C viruses, Ebola virus, Marburg virus, Dengue virus, Zika virus, West Nile virus, and Japanese encephalitis virus
  • The direct binding of the viruses by CD365 occurs via phosphatildyl-serine exposed on viral envelopes
  • Polymorphisms within human CD365 gene (HAVCR1) are associated with susceptibility to infection and the disease severity
  • CD365 has also been implicated in the T cell co-stimulation
  • CD365 is primarily expressed in epithelial cells
  • It is also highly expressed in A549, 769-P and Caco-2 and cell lines
  • CD365 exists also as a soluble protein generated by metalloproteinase mediated proteolytic cleavage of the surface protein.

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Antigen:
CD365 (TIM1)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q96D42

Gene Symbols:
Havcr1

Immunogen:
IgV domain of human CD365

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
1D12-TIM1

Conjugate:
PE

Gene:
Havcr1

Gene Alias:
AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26762

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

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Antigen:
__

Classification:
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Concentration:
__

Formulation:
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Gene Accession No.:
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Gene Symbols:
__

Immunogen:
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Quantity:
1 oz.

Primary or Secondary:
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Target Species:
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Clone:
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Gene:
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Gene Alias:
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__

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Antigen:
Arginase 1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P05089, Q61176

Gene Symbols:
ARG1

Immunogen:
E.coli-derived recombinant mouse Arginase 1

Quantity:
25μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
A1exF5

Conjugate:
PE

Gene:
ARG1

Gene Alias:
AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11846, 383

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Fischer Scientific

12-369-782

--


Antigen:
Arginase 1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P05089, Q61176

Gene Symbols:
ARG1

Immunogen:
E.coli-derived recombinant mouse Arginase 1

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
A1exF5

Conjugate:
PE

Gene:
ARG1

Gene Alias:
AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11846, 383

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid