CD318 (CDCP1) Monoclonal Antibody (CSTEM26), PE, eBioscience™, Invitrogen™

Description

• This monoclonal antibody CSTEM26 reacts with human CD318, also known as CUB domain-containing protein 1 (CDCP1) and Trask
• Applications Reported: This CSTEM26 antibody has been reported for use in flow cytometric analysis
• Applications Tested: This CSTEM26 antibody has been pre-diluted and tested by flow cytometric analysis of normal human induced pluripotent stem cells
• This may be used at 5 μL (0.25 μg) per test
• A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
• Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
• Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
• Filtration: 0.2 μm post-manufacturing filtered
• CDCP1 is a transmembrane protein containing three extracellular CUB domains
• It is found to be overexpressed in colon and lung cancers
• Its expression level is correlated with the metastatic ability of carcinoma cells
• CDCP1 is located on the cell surface
• It has been shown to be tyrosine phosphorylated in a cancer cell line
• Alternatively spliced transcript variants encoding distinct isoforms have been reported.