13-838-8

Connexin 43 Monoclonal Antibody (CX-1B1), Alexa Fluor™ 488, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 13-838-8-Each-of-1 In Stock ₹ 40,050.00

13-838-8 - Each of 1

₹ 40,050.00

In Stock

Quantity

1

Base Price: ₹ 40,050.00

GST (18%): ₹ 7,209.00

Total Price: ₹ 47,259.00

Antigen

Connexin 43

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 4.5mg/mL BSA and 0.1% sodium azide; pH 7.4

Gene Accession No.

P08050, P17302, P23242, Q6S9C0

Gene Symbols

GJA1

Immunogen

Synthetic peptide corresponding to a cytoplasmic sequence located near the C-terminus of rat Connexin 43.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

CX-1B1

Conjugate

Alexa Fluor 488

Gene

GJA1

Gene Alias

alpha 1 connexin; AU042049; AVSD3; AW546267; CMDR; Cnx43; connexin 43; connexin43; connexin-43; cx43; Cx-43; cx43 protein; cx43a1; Cx43alpha1; CXA1; Cxn-43; DFNB38; EKVP; etID309742.9; gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction membrane channel protein; gap junction membrane channel protein alpha 1; gap junction protein; gap junction protein alpha 1; gap junction protein connexin 43; gap junction protein, alpha 1; gap junction protein, alpha 1, 43 kD (connexin 43); gap junction protein, alpha 1, 43kDa; gap junction protein, alpha 1, 43kDa (connexin 43); gja1; Gja-1; GJAL; HLHS1; HSS; Npm1; ODD; ODDD; ODOD; PPKCA; SDTY3; shf; Short fin protein; sof; stopsel; stp; Syndactyly type III; vascular smooth muscle connexin43; Vascular smooth muscle connexin-43; zfCx43.3

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

14609, 24392, 2697, 403418

Content And Storage

4° C

Form

Liquid

Description

  • Connexin 43 (Cx43) is a member of the gap junction protein family
  • Connexins assemble as a hexamer and are transported to the plasma membrane to create a hemichannel that can associate with hemichannels on nearby cells to create cell-to-cell channels
  • Clusters of these channels assemble to make gap junctions
  • Gap junction communication is important in development and regulation of cell growth
  • Phosphorylation of Cx43 is important in regulating assembly and function of gap junctions
  • Ser368 of Cx43 is phosphorylated by protein kinase C (PKC) after activation by phorbol esters, which decreases cell-to-cell communication
  • Src can interact with and phosphorylate Cx43 to alter gap junction communication
  • GFAP are membrane-spanning proteins that facilitate the transfer of ions and small molecules between cells
  • According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta
  • Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development
  • Connexin 43 is also targeted by several protein kinases that regulate myocardial cell-cell coupling
  • A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5
  • Mutations in the GFAP gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy, oculodentodigital dysplasia and heart malformations
  • Alternatively spliced transcript variants of GFAP have been found.

Compare Similar Items

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Img

Invitrogen

13-838-8

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Antigen:
Connexin 43

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 4.5mg/mL BSA and 0.1% sodium azide; pH 7.4

Gene Accession No.:
P08050, P17302, P23242, Q6S9C0

Gene Symbols:
GJA1

Immunogen:
Synthetic peptide corresponding to a cytoplasmic sequence located near the C-terminus of rat Connexin 43.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
CX-1B1

Conjugate:
Alexa Fluor 488

Gene:
GJA1

Gene Alias:
alpha 1 connexin; AU042049; AVSD3; AW546267; CMDR; Cnx43; connexin 43; connexin43; connexin-43; cx43; Cx-43; cx43 protein; cx43a1; Cx43alpha1; CXA1; Cxn-43; DFNB38; EKVP; etID309742.9; gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction membrane channel protein; gap junction membrane channel protein alpha 1; gap junction protein; gap junction protein alpha 1; gap junction protein connexin 43; gap junction protein, alpha 1; gap junction protein, alpha 1, 43 kD (connexin 43); gap junction protein, alpha 1, 43kDa; gap junction protein, alpha 1, 43kDa (connexin 43); gja1; Gja-1; GJAL; HLHS1; HSS; Npm1; ODD; ODDD; ODOD; PPKCA; SDTY3; shf; Short fin protein; sof; stopsel; stp; Syndactyly type III; vascular smooth muscle connexin43; Vascular smooth muscle connexin-43; zfCx43.3

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
14609, 24392, 2697, 403418

Content And Storage:
4° C

Form:
Liquid

Img

Invitrogen

13-840-0

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Antigen:
beta Catenin

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
P35222, Q02248

Gene Symbols:
CTNNB1

Immunogen:
Fusion protein consisting of the maltose binding protein fused to a 100 amino acid segment of the C-terminus of chicken beta-Catenin.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Chicken, Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
CAT-5H10

Conjugate:
Unconjugated

Gene:
CTNNB1

Gene Alias:
armadillo; armadillo homolog; Bcatenin; b-catenin; beta 1 88kDa; beta catenin; Betacatenin; beta-catenin; beta-catenin 1; Bfc; C20orf33; Cadherin associated protein; catenin; catenin (cadherin associated protein), beta 1; catenin (cadherin associated protein), beta 1, 88kDa; catenin (cadherin-associated protein) beta 1; catenin (cadherin-associated protein), beta 1; catenin (cadherin-associated protein), beta 1, 88kDa; Catenin b 1; Catenin b1; catenin beta; catenin beta 1; catenin beta 1 L homeolog; Catenin beta1; Catenin beta-1; Catenin β 1; Catenin β1; Catnb; CHBCAT; CTNB1; CTNNB; ctnnb1; ctnnb1.L; ctnnb1-a; ctnnb1-b; dJ633O20.1; DKFZp686D02253; FLJ25606; FLJ37923; id:ibd2058; Mesc; MRD19; NAP; NYD-SP19; OK/SW-cl.35; OTTHUMP00000209289; P14L; PP8304; PRO2286; RP5-1118M15.1; wu:fb73e10; wu:fi81c06; wu:fk25h01; XELAEV_18031149mg; β catenin; βcatenin

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12387, 1499, 395964

Content And Storage:
-20°C

Form:
Liquid

Img

Invitrogen

13-850-0

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Antigen:
gamma Catenin

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
P14923, Q02257

Gene Symbols:
JUP

Immunogen:
Fusion protein consisting of the maltose binding protein fused to full length human plakoglobin protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
PG-11E4

Conjugate:
Unconjugated

Gene:
JUP

Gene Alias:
ARVD12; catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; cb80; cell-adhesion protein plakoglobin; Ctnng; D930025P04Rik; danPG; Desmoplakin III; desmoplakin-3; desmosomal protein; DP3; DPIII; fb11b06; gama-catenin; gamma-catenin; gamma-catenin (plakoglobin); junction plakoglobin; junction plakoglobin a; Jup; jup protein; jupa; OTTHUMP00000164735; PDGB; PG; PKGB; plakoglobin; wu:fb11b06

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16480, 3728

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

13-864-300

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Product Type:
Deepwell Microplate

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