14-043-937
CD43 Monoclonal Antibody (eBio84-3C1 (84-3C1)), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-043-937-Each-of-1 | In Stock | ₹ 1,17,388.32 |
14-043-937 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,17,388.32
GST (18%): ₹ 21,129.898
Total Price: ₹ 1,38,518.218
Antigen
CD43
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P16150
Gene Symbols
SPN
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6693
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone
eBio84-3C1 (84-3C1)
Conjugate
Unconjugated
Gene
SPN
Gene Alias
3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen
Host Species
Mouse
Quantity
2 mg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The monoclonal antibody ebio84-3C1 reacts with CD43, which is also known as leukosialin, galactoglycoprotein and sialophorin
- CD43 is a sialomucin which like many mucins can have both adhesive and anti-adhesive functions
- Expression of CD43 is found on most leukocytes except resting B lymphocytes
- Proteolytic processing upon activation decreases surface expression
- CD43 is involved in activation of T cells, B cells, NK cells, and monocytes
- The counter-receptor for CD43 is CD169/SIGLEC-1, which is expressed on macrophages
- Applications Reported: This eBio84-3C1 (84-3C1) antibody has been reported for use in flow cytometric analysis, western blotting, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections
- Applications Tested: This eBio84-3C1 (84-3C1) antibody has been tested by flow cytometric analysis of human peripheral blood cells and by immunohistochemistry of formalin-fixed paraffin embedded human spleen using low pH antigen retreival at less than or equal to 20 μg/mL
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- CD43 (leukosialin, sialophorin) is a transmembrane mucin-like protein with high negative charge, expressed on the surface of most hematopoietic cells
- CD43 contributes to a repulsive barrier that interferes with cellular adhesion, however, in certain cases also promotes leukocyte aggregation
- By interaction with actin-binding proteins ezrin and moesin CD43 plays a regulatory role in remodeling T-cell morphology and regulates cell-cell interactions during lymphocyte traffic
- CD43 signaling both enhances LFA-1 adhesiveness and counteracts LFA-1 induction via other receptors
- Expression of CD43 causes induction of functionally active tumor suppressor p53 protein, but in case of p53 and ARF deficiency CD43 promotes tumor proliferation and viability
- CD43 appears to be an important modulator of leukocyte functions
- Diseases associated with CD43 dysfunction include Wiscott-Aldrich Syndrome and Adenoid Basal Cell Carcinoma.
Compare Similar Items
Show Difference
Antigen: CD43
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P16150
Gene Symbols: SPN
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6693
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: eBio84-3C1 (84-3C1)
Conjugate: Unconjugated
Gene: SPN
Gene Alias: 3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD43
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P16150
Gene Symbols:
SPN
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6693
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
eBio84-3C1 (84-3C1)
Conjugate:
Unconjugated
Gene:
SPN
Gene Alias:
3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: LYVE1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q8BHC0
Gene Symbols: Lyve1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114332
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
Clone: ALY7
Conjugate: Unconjugated
Gene: Lyve1
Gene Alias: 1200012G08Rik; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; CRSBP1; CRSBP-1; extra cellular link domain-containing 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; HAR; hyaluronic acid receptor; lymphatic endothelial hyaluronan receptor LYVE-1; lymphatic vessel endothelial HA receptor-1; lymphatic vessel endothelial HA recptor-1; lymphatic vessel endothelial hyaluronan receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1; LYVE-1; sLyve 1; sLyve1; soluble LYVE 1; soluble LYVE1; UNQ230/PRO263; XLKD1
Host Species: Rat
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
LYVE1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q8BHC0
Gene Symbols:
Lyve1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114332
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
Clone:
ALY7
Conjugate:
Unconjugated
Gene:
Lyve1
Gene Alias:
1200012G08Rik; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; CRSBP1; CRSBP-1; extra cellular link domain-containing 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; HAR; hyaluronic acid receptor; lymphatic endothelial hyaluronan receptor LYVE-1; lymphatic vessel endothelial HA receptor-1; lymphatic vessel endothelial HA recptor-1; lymphatic vessel endothelial hyaluronan receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1; LYVE-1; sLyve 1; sLyve1; soluble LYVE 1; soluble LYVE1; UNQ230/PRO263; XLKD1
Host Species:
Rat
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD45RO
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P08575
Gene Symbols: PTPRC
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5788
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
Clone: UCHL1
Conjugate: Unconjugated
Gene: PTPRC
Gene Alias: B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD45RO
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P08575
Gene Symbols:
PTPRC
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5788
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin)
Clone:
UCHL1
Conjugate:
Unconjugated
Gene:
PTPRC
Gene Alias:
B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD45RA
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P08575
Gene Symbols: PTPRC
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5788
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
Clone: HI100
Conjugate: Unconjugated
Gene: PTPRC
Gene Alias: B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; Leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T100; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD45RA
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P08575
Gene Symbols:
PTPRC
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5788
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin)
Clone:
HI100
Conjugate:
Unconjugated
Gene:
PTPRC
Gene Alias:
B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; Leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T100; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ