14-181-937
CD181 (CXCR1) Monoclonal Antibody (eBio8F1-1-4 (8F1-1-4)), eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 14-181-937-Each | In Stock | ₹ 99,818.57 |
14-181-937 - Each
In Stock
Quantity
1
Base Price: ₹ 99,818.57
GST (18%): ₹ 17,967.343
Total Price: ₹ 1,17,785.913
Antigen
CD181 (CXCR1)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P25024
Gene Symbols
CXCR1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3577
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry
Clone
eBio8F1-1-4 (8F1-1-4)
Conjugate
Unconjugated
Gene
CXCR1
Gene Alias
C Cmotif chemokine; C X C motif chemokine; C-C; CC motif chemokine; C-C-CKR-1; CCmotif chemokine; CD128; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; CXC; CXC chemokine receptor 1; C-X-C chemokine receptor type 1; CXC motif chemokine; C-X-C motif chemokine receptor 1; CXCR1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor; IL-8 Receptor alpha; IL-8 Receptor IL-RA; IL-8 receptor type 1; IL-8R A; IL8R1; Il8ra; IL8RBA; IL-RA; interleukin 8 receptor; interleukin 8 receptor alpha; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
Host Species
Mouse
Quantity
2 mg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- The eBio8F1-1-4 MAb reacts with human CD181 (CXCR1, IL-8Ralpha)
- CD181 is a 67-70 kDa member of the 7-transmembrane spanning G-protein coupled receptor (GPCR) family
- CD181 is expressed as a homodimer, or a heterodimer with CD182 (CXCR2, IL-8Rbeta) and is expressed on granulocytes, NK cells, a subset of T cells, mast cells, monocytes, endothelial cells, megakaryocytes and oligodendrocytes
- Binding of it's ligands, which include IL-8, NAP-2, GCP-2 and GRO-alpha, induces several biological outcomes such as cell activation, chemotaxis, proliferation and angiogenesis
- There are several functional differences between CD181 and CD182
- Both receptors are able to mediate chemotaxis and intracellular calcium changes, but only CD181 mediates phospolipase D activation and respiratory burst
- Furthermore, studies have shown that IL-8 predominantly mediates its effects on neutrophil function through CD181
- CXCR1 is a member of the G-protein-coupled receptor family
- This protein is a receptor for interleukin 8 (IL8)
- It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system
- Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord
- This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
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Antigen: CD181 (CXCR1)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P25024
Gene Symbols: CXCR1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3577
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: eBio8F1-1-4 (8F1-1-4)
Conjugate: Unconjugated
Gene: CXCR1
Gene Alias: C Cmotif chemokine; C X C motif chemokine; C-C; CC motif chemokine; C-C-CKR-1; CCmotif chemokine; CD128; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; CXC; CXC chemokine receptor 1; C-X-C chemokine receptor type 1; CXC motif chemokine; C-X-C motif chemokine receptor 1; CXCR1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor; IL-8 Receptor alpha; IL-8 Receptor IL-RA; IL-8 receptor type 1; IL-8R A; IL8R1; Il8ra; IL8RBA; IL-RA; interleukin 8 receptor; interleukin 8 receptor alpha; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD181 (CXCR1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P25024
Gene Symbols:
CXCR1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3577
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBio8F1-1-4 (8F1-1-4)
Conjugate:
Unconjugated
Gene:
CXCR1
Gene Alias:
C Cmotif chemokine; C X C motif chemokine; C-C; CC motif chemokine; C-C-CKR-1; CCmotif chemokine; CD128; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; CXC; CXC chemokine receptor 1; C-X-C chemokine receptor type 1; CXC motif chemokine; C-X-C motif chemokine receptor 1; CXCR1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor; IL-8 Receptor alpha; IL-8 Receptor IL-RA; IL-8 receptor type 1; IL-8R A; IL8R1; Il8ra; IL8RBA; IL-RA; interleukin 8 receptor; interleukin 8 receptor alpha; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD181 (CXCR1)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P25024
Gene Symbols: CXCR1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3577
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: eBio8F1-1-4 (8F1-1-4)
Conjugate: Unconjugated
Gene: CXCR1
Gene Alias: C Cmotif chemokine; C X C motif chemokine; C-C; CC motif chemokine; C-C-CKR-1; CCmotif chemokine; CD128; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; CXC; CXC chemokine receptor 1; C-X-C chemokine receptor type 1; CXC motif chemokine; C-X-C motif chemokine receptor 1; CXCR1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor; IL-8 Receptor alpha; IL-8 Receptor IL-RA; IL-8 receptor type 1; IL-8R A; IL8R1; Il8ra; IL8RBA; IL-RA; interleukin 8 receptor; interleukin 8 receptor alpha; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
Host Species: Mouse
Quantity: 10 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD181 (CXCR1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P25024
Gene Symbols:
CXCR1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3577
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBio8F1-1-4 (8F1-1-4)
Conjugate:
Unconjugated
Gene:
CXCR1
Gene Alias:
C Cmotif chemokine; C X C motif chemokine; C-C; CC motif chemokine; C-C-CKR-1; CCmotif chemokine; CD128; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; CXC; CXC chemokine receptor 1; C-X-C chemokine receptor type 1; CXC motif chemokine; C-X-C motif chemokine receptor 1; CXCR1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor; IL-8 Receptor alpha; IL-8 Receptor IL-RA; IL-8 receptor type 1; IL-8R A; IL8R1; Il8ra; IL8RBA; IL-RA; interleukin 8 receptor; interleukin 8 receptor alpha; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
Host Species:
Mouse
Quantity:
10 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: __
Classification: Animal Origin-Free
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: Storage conditions: 15-30° CShipping conditions: AmbientShelf life: 24 months from date of manufacture
Form: Liquid
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: 500 mL
Primary or Secondary: __
Target Species: __
Product Type: Hanks' Balanced Salt Solution (HBSS)
Isotype: __
Antigen:
__
Classification:
Animal Origin-Free
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
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Content And Storage:
Storage conditions: 15-30° CShipping conditions: AmbientShelf life: 24 months from date of manufacture
Form:
Liquid
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
500 mL
Primary or Secondary:
__
Target Species:
__
Product Type:
Hanks' Balanced Salt Solution (HBSS)
Isotype:
__
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
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Clone: __
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Formulation:
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Gene Accession No.:
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Gene Symbols:
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Purification Method:
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Regulatory Status:
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Gene ID (Entrez):
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Content And Storage:
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Form:
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Applications:
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Clone:
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Conjugate:
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Gene:
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