14-304-282
CD304 (Neuropilin-1) Monoclonal Antibody (XML1Y1), eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 14-304-282-Each | In Stock | ₹ 32,311.73 |
14-304-282 - Each
In Stock
Quantity
1
Base Price: ₹ 32,311.73
GST (18%): ₹ 5,816.111
Total Price: ₹ 38,127.841
Antigen
CD304 (Neuropilin-1)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
O14786, P97333
Gene Symbols
NRP1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18186, 8829
Content And Storage
4° C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen)
Clone
XML1Y1
Conjugate
Unconjugated
Gene
NRP1
Gene Alias
A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description The MAb XML1Y1 recognizes CD304 (Neuropilin-1), a type 1 transmembrane glycoprotein present on the surface of multiple cell types, including: regulatory T cells (Tregs), NKT cells, DC, certain types of stem cells, neurons, endothelial cells, and some neoplastic cells
- Neuropilin-1, in complex with plexins, serves as a co-receptor for type 3 semaphorins in growing neurons
- It is also involved in the process of angiogenesis being a part of a functional receptor for VEGF in endothelial cells
- In mouse Neuropilin-1 is expressed on thymus-derived natural Tregs but not peripherally induced Treg cells
- In addition, transient expression on recently activated non-regulatory T cells has been observed
- Neuropilin-1 has been used as a marker of recent thymic emigrants in the mouse iNKT cell population
- It has been shown that Neuropilin-1 forms a complex with TGF beta receptors, activating TGF beta latent form (LAP-TGF beta 1) and augmenting canonic Smad2/3 signaling
- This XML1Y1 antibody recognizes neuropilin-1 isoforms 1 and 2
- Neuropilin 1 is a 923 amino acid containing membrane bound coreceptor to a tyrosine kinase receptor belonging to the neuropilin family with two CUB domains, two F5/8 type C domains and a MAM domain
- Neuropilin 1 forms a heterodimer with NRP2 (Neuropilin 2) and is known to bind to plexin (PLXNB1) to form semaphorin receptors
- Expressed mostly in the nervous system this receptor is implicated in a wide range of functions including in the development of the cardiovascular system, angiogenesis, repulsive axon guidance, formation of certain neuronal circuits, cell survival, control of neuronal migration and organogenesis outside the nervous system
- This semaphorin receptor functions as receptors for both the semaphorins and vascular endothelial growth factor and is also a regulator of VEGF-induced angiogenesis
- Neuropilin 1 may be involved in aggressive advanced prostate carcinoma and in the progression of breast cancer.
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Show Difference
Antigen: CD304 (Neuropilin-1)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O14786, P97333
Gene Symbols: NRP1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18186, 8829
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen)
Clone: XML1Y1
Conjugate: Unconjugated
Gene: NRP1
Gene Alias: A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD304 (Neuropilin-1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O14786, P97333
Gene Symbols:
NRP1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18186, 8829
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen)
Clone:
XML1Y1
Conjugate:
Unconjugated
Gene:
NRP1
Gene Alias:
A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: Store in refrigerator (2–8°C).
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: 2 mL
Primary or Secondary: __
Target Species: __
Product Type: Carboxylic Acid Magnetic Bead
Isotype: __
Antigen:
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Classification:
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Concentration:
__
Formulation:
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Gene Accession No.:
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Gene Symbols:
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Purification Method:
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Regulatory Status:
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Gene ID (Entrez):
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Content And Storage:
Store in refrigerator (2–8°C).
Form:
__
Applications:
__
Clone:
__
Conjugate:
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Gene:
__
Gene Alias:
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Host Species:
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Quantity:
2 mL
Primary or Secondary:
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Target Species:
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Product Type:
Carboxylic Acid Magnetic Bead
Isotype:
__
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: Store in refrigerator (2–8°C).
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: 10 mL
Primary or Secondary: __
Target Species: __
Product Type: Carboxylic Acid Magnetic Bead
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
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Gene ID (Entrez):
__
Content And Storage:
Store in refrigerator (2–8°C).
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
10 mL
Primary or Secondary:
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Target Species:
__
Product Type:
Carboxylic Acid Magnetic Bead
Isotype:
__
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Applications: __
Clone: __
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Purification Method:
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Regulatory Status:
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Gene ID (Entrez):
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Content And Storage:
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Form:
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Applications:
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Clone:
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Conjugate:
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Gene:
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Gene Alias:
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Host Species:
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Quantity:
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Primary or Secondary:
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Target Species:
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Product Type:
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Isotype:
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