14-592-380

SOX10 Monoclonal Antibody (20B7), eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 14-592-380-Each-of-1 In Stock ₹ 15,041.00

14-592-380 - Each of 1

₹ 15,041.00

In Stock

Quantity

1

Base Price: ₹ 15,041.00

GST (18%): ₹ 2,707.38

Total Price: ₹ 17,748.38

Antigen

SOX10

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

O55170, P56693, Q04888

Gene Symbols

SOX10

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20665, 29361, 6663

Content And Storage

4° C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone

20B7

Conjugate

Unconjugated

Gene

SOX10

Gene Alias

cls; cls/sox10; colorless; colourless; colourless/sox10; DOM; dominant megacolon; dominant megacolon, mouse, human homolog of; golas; gos; HMG-box transcription factor Sox10; MGC15649; PCWH; Protein SOX-21; SOX10; Sox-10; sox10 protein; sox10b; Sox21; SOX9; SRY; SRY (sex determining region Y)-box 10; SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal); SRY box 10; SRY-box 10; SRY-box containing gene 10; SRY-box containing protein 10; SRY-box transcription factor 10; SRY-related HMG-box gene 10; transcription factor SOX-10; Transcription factor SOX-M; WS2E; WS4; WS4C; zgc:100757

Host Species

Mouse

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description The MAb 20B7 recognizes Sox10, is a member of the Sox superfamily (SRY-related HMG-box) that contain a DNA binding domain (high-mobility group domain) and functions as a transcription factor
  • Initially, Sox10 expression is localized to the developing neural crest and peripheral nervous system, but later is expressed in glial progenitors and mature oligodendrocytes
  • Sox10 is involved in stem cell maintenance, melanocyte differentiation, as well as central and peripheral gliogenesis and neurogenesis
  • Sox10 regulation of downstream proteins such as MASH1, PHOX2B, PDGF-alpha, and MITF is dependent on expression level
  • Sox10 is also expressed in multipotent vascular stem cells, melanomas, and gliomas
  • The 20B7 antibody is reported to recognize human and rat Sox 10, and based on homology should recognize mouse Sox10
  • SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate
  • This protein may act as a transcriptional activator after forming a protein complex with other proteins
  • It acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development
  • Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Compare Similar Items

Show Difference

Img

Invitrogen

14-592-380

--


Antigen:
SOX10

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
O55170, P56693, Q04888

Gene Symbols:
SOX10

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20665, 29361, 6663

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
20B7

Conjugate:
Unconjugated

Gene:
SOX10

Gene Alias:
cls; cls/sox10; colorless; colourless; colourless/sox10; DOM; dominant megacolon; dominant megacolon, mouse, human homolog of; golas; gos; HMG-box transcription factor Sox10; MGC15649; PCWH; Protein SOX-21; SOX10; Sox-10; sox10 protein; sox10b; Sox21; SOX9; SRY; SRY (sex determining region Y)-box 10; SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal); SRY box 10; SRY-box 10; SRY-box containing gene 10; SRY-box containing protein 10; SRY-box transcription factor 10; SRY-related HMG-box gene 10; transcription factor SOX-10; Transcription factor SOX-M; WS2E; WS4; WS4C; zgc:100757

Host Species:
Mouse

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

14-593-437

--


Antigen:
AIRE

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9Z0E3

Gene Symbols:
Aire

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11634

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
5H12

Conjugate:
Unconjugated

Gene:
Aire

Gene Alias:
Aire; AIRE protein; AIRE1; APECED; APECED protein; APECED protein homolog; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog; Autoimmune regulator; autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator AIRE1a; LOW QUALITY PROTEIN: autoimmune regulator; OTTHUMP00000109529; PGA1

Host Species:
Rat

Quantity:
2 mg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2c κ

Img

Fischer Scientific

14-593-495

--


Antigen:
AIRE

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9Z0E3

Gene Symbols:
Aire

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11634

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
5H12

Conjugate:
Unconjugated

Gene:
Aire

Gene Alias:
Aire; AIRE protein; AIRE1; APECED; APECED protein; APECED protein homolog; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog; Autoimmune regulator; autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator AIRE1a; LOW QUALITY PROTEIN: autoimmune regulator; OTTHUMP00000109529; PGA1

Host Species:
Rat

Quantity:
10 mg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2c κ

Img

Invitrogen

14-596-937

--


Antigen:
CD270 (HVEM)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q92956

Gene Symbols:
TNFRSF14

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8764

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Clone:
eBioHVEM-122

Conjugate:
Unconjugated

Gene:
TNFRSF14

Gene Alias:
Atar; CD270; CD40-like protein; herpes virus entry mediator; herpes virus entry mediator A; Herpesvirus entry mediator A; HGNC:11912; HVEA; Hvem; LIGHTR; RP3-395M20.6; sCD2710; TNF receptor superfamily member 14; Tnfrs14; TNFRSF14; TR2; tumo; Tumor necrosis factor receptor superfamily member 14; tumor necrosis factor receptor superfamily, member 14; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); Tumor necrosis factor receptor-like 2; tumor necrosis factor receptor-like gene2; UNQ329/PRO509

Host Species:
Mouse

Quantity:
2 mg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1