Chorionic Gonadotropin Monoclonal Antibody (FB12), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-650-837-Each-of-1 | In Stock | ₹ 1,17,388.32 |
14-650-837 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,17,388.32
GST (18%): ₹ 21,129.898
Total Price: ₹ 1,38,518.218
Antigen
Chorionic Gonadotropin
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P01215, P0DN86
Gene Symbols
CGA, CGB3, CGB5, CGB8
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1081, 1082, 93659, 94115
Content And Storage
4° C
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone
FB12
Conjugate
Unconjugated
Gene
CGA
Gene Alias
anterior pituitary glycoprotein hormones common subunit alpha; CGA; CG-alpha; CGB; CGB3; CGB5; CGB7; CGB8; CG-beta; Choriogonadotropin alpha chain; choriogonadotropin subunit beta; Choriogonadotropin subunit beta 3; chorionic gonadotrophin chain beta; chorionic gonadotrophin subunit alpha; chorionic gonadotropin beta 3 subunit; chorionic gonadotropin beta 5 subunit; chorionic gonadotropin beta 8 subunit; chorionic gonadotropin beta chain; chorionic gonadotropin beta subunit; chorionic gonadotropin beta subunit 3; chorionic gonadotropin beta subunit 5; chorionic gonadotropin beta subunit 8; chorionic gonadotropin chain beta; chorionic gonadotropin human; chorionic gonadotropin, alpha polypeptide; chorionic gonadotropin, beta polypeptide; chorionic gonadotropin, beta polypeptide 5; chorionic gonadotropin, beta polypeptide 8; follicle-stimulating hormone alpha chain; follicle-stimulating hormone alpha subunit; follitropin alpha chain; FSHA; FSH-alpha; Glycoprotein hormones alpha chain; gl
Host Species
Mouse
Quantity
2 mg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- This FB12 MAb reacts with human Chorionic Gonadotropin (hCG)
- This secreted glycoprotein is composed of an alpha subunit, which is common to other peptide hormones such as luteinizing hormone (LH), follicle stimulating hormone (FSH) and thyroid stimulating hormone (TSH), and a beta subunit which determines the specificity of the hormone
- FB12 recognizes both the intact hCG (composed of the alpha and beta subunits) as well as the free beta subunit, highly expressed in both choriocarcinoma and the serum of pregnant women
- hCG is normally expressed by trophoblastoid cells (syncytiotrophoblasts and extravillous cytotrophoblasts) that are responsible for maintenance of the corpus luteum during early gestation
- hCG plays an important role in the regulation of angiogenesis through activation of the PI3K/mTOR pathway, resulting in upregulation of vascular endothelial growth factor (VEGF)
- Ectoptic expression of hCG has also been reported in multiple types of cancer (bladder, lung, breast, pancreas, renal)
- Human chorionic gonadotropin (hCG) is a placental hormone that stimulates secretion of the pregnancy-sustaining steroid progesterone
- hCG is a member of a family of glycoprotein hormones including pituitary hormones lutropin (luteinizing hormone;LH), follitropin (follicle-stimulating hormone; FSH) and thyrotropin (thyroid-stimulating hormone; TSH)
- Members of this family are all composed of disulfide-rich heterodimers with two dissimilar subunits namely alpha- and beta-subunits
- The alpha subunit is common to all the members of the family within a given species
- The beta subunits are distinct in each of the horomones and confer the receptor and biological specificity.
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Antigen: Chorionic Gonadotropin
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P01215, P0DN86
Gene Symbols: CGA, CGB3, CGB5, CGB8
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1081, 1082, 93659, 94115
Content And Storage: 4° C
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone: FB12
Conjugate: Unconjugated
Gene: CGA
Gene Alias: anterior pituitary glycoprotein hormones common subunit alpha; CGA; CG-alpha; CGB; CGB3; CGB5; CGB7; CGB8; CG-beta; Choriogonadotropin alpha chain; choriogonadotropin subunit beta; Choriogonadotropin subunit beta 3; chorionic gonadotrophin chain beta; chorionic gonadotrophin subunit alpha; chorionic gonadotropin beta 3 subunit; chorionic gonadotropin beta 5 subunit; chorionic gonadotropin beta 8 subunit; chorionic gonadotropin beta chain; chorionic gonadotropin beta subunit; chorionic gonadotropin beta subunit 3; chorionic gonadotropin beta subunit 5; chorionic gonadotropin beta subunit 8; chorionic gonadotropin chain beta; chorionic gonadotropin human; chorionic gonadotropin, alpha polypeptide; chorionic gonadotropin, beta polypeptide; chorionic gonadotropin, beta polypeptide 5; chorionic gonadotropin, beta polypeptide 8; follicle-stimulating hormone alpha chain; follicle-stimulating hormone alpha subunit; follitropin alpha chain; FSHA; FSH-alpha; Glycoprotein hormones alpha chain; gl
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
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