16-702-738
IL-2 Monoclonal Antibody (AB12-3G4), Functional Grade, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 16-702-738-Each-of-1 | In Stock | ₹ 1,82,670.60 |
16-702-738 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,82,670.60
GST (18%): ₹ 32,880.708
Total Price: ₹ 2,15,551.308
Antigen
IL-2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.2
Gene Accession No.
P60568
Gene Symbols
IL2
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3558
Content And Storage
4° C
Form
Liquid
Applications
Functional Assay, Neutralization
Clone
AB12-3G4
Conjugate
Functional Grade
Gene
IL2
Gene Alias
aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Host Species
Mouse
Quantity
5 mg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: This AB12-3G4 monoclonal antibody reacts with and inhibits the bioactivity of human IL-2
- IL-2 is a 15 kDa cytokine expressed by B cells, T cells, and dendritic cells
- IL-2 signals via a heterotrimeric receptor (CD25) and results in the activation of Jak/STAT pathways
- IL-2 plays a critical role in the proliferation, activation, and differentiation of T cells
- The development of CD4+CD25+ regulatory T cells is especially dependent on the presence of IL-2, making it an important immunoregulatory cytokine
- Applications Reported: This AB12-3G4 monoclonal antibody inhibits the bioactivity of human IL-2
- Applications Tested: The ND50 of AB12-3G4, as determined by the neutralization of Human IL-2-induced proliferation of the CTLL-2 cell line, is less than or equal to 60 ng/mL in the presence of 10 ng/mL Human IL-2 Recombinant Protein
- The neutralization dose of this antibody will vary depending on cell type, assay method, and cytokine concentration
- Storage and handling: Use in a sterile environment
- Filtration: 0.2 μm post-manufacturing filtered
- Purity: Greater than 90%, as determined by SDS-PAGE
- Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay
- Aggregation: Less than 10%, as determined by HPLC
- Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages
- IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7)
- The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene
- The targeted disruption of a gene similar to IL-2 in mice leads to an μgcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
Compare Similar Items
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Antigen: IL-2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: P60568
Gene Symbols: IL2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3558
Content And Storage: 4° C
Form: Liquid
Applications: Functional Assay, Neutralization
Clone: AB12-3G4
Conjugate: Functional Grade
Gene: IL2
Gene Alias: aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Host Species: Mouse
Quantity: 5 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
IL-2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
P60568
Gene Symbols:
IL2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3558
Content And Storage:
4° C
Form:
Liquid
Applications:
Functional Assay, Neutralization
Clone:
AB12-3G4
Conjugate:
Functional Grade
Gene:
IL2
Gene Alias:
aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Host Species:
Mouse
Quantity:
5 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: IL-4
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: P20096
Gene Symbols: Il4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 287287
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Western Blot
Clone: OX81
Conjugate: Functional Grade
Gene: Il4
Gene Alias: B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
IL-4
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
P20096
Gene Symbols:
Il4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
287287
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Western Blot
Clone:
OX81
Conjugate:
Functional Grade
Gene:
Il4
Gene Alias:
B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: IL-4
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: P05112
Gene Symbols: Il4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3565
Content And Storage: 4° C
Form: Liquid
Applications: Functional Assay, Neutralization
Clone: MP4-25D2
Conjugate: Functional Grade
Gene: Il4
Gene Alias: B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
Host Species: Rat
Quantity: 5 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
IL-4
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
P05112
Gene Symbols:
Il4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3565
Content And Storage:
4° C
Form:
Liquid
Applications:
Functional Assay, Neutralization
Clone:
MP4-25D2
Conjugate:
Functional Grade
Gene:
Il4
Gene Alias:
B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
Host Species:
Rat
Quantity:
5 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: IL-6
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: P08505
Gene Symbols: Il6
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16193
Content And Storage: 4° C
Form: Liquid
Applications: Functional Assay, Immunostaining, Neutralization
Clone: MP5-20F3
Conjugate: Functional Grade
Gene: Il6
Gene Alias: B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
Host Species: Rat
Quantity: 5 mg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
IL-6
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
P08505
Gene Symbols:
Il6
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16193
Content And Storage:
4° C
Form:
Liquid
Applications:
Functional Assay, Immunostaining, Neutralization
Clone:
MP5-20F3
Conjugate:
Functional Grade
Gene:
Il6
Gene Alias:
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
Host Species:
Rat
Quantity:
5 mg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ