16-717-8050

IL-17A Monoclonal Antibody (eBio64CAP17), Functional Grade, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 16-717-8050-Each-of-1 In Stock ₹ 12,35,486.40

16-717-8050 - Each of 1

₹ 12,35,486.40

In Stock

Quantity

1

Base Price: ₹ 12,35,486.40

GST (18%): ₹ 2,22,387.552

Total Price: ₹ 14,57,873.952

Antigen

IL-17A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative; pH 7.2

Gene Accession No.

Q16552

Gene Symbols

IL17A

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3605

Content And Storage

4° C

Form

Liquid

Applications

Functional Assay, Immunostaining, Neutralization

Clone

eBio64CAP17

Conjugate

Functional Grade

Gene

IL17A

Gene Alias

Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A

Host Species

Mouse

Quantity

50 mg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection
  • IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217)
  • High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts
  • In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2
  • In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils
  • Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor
  • IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).

Compare Similar Items

Show Difference

Img

Fischer Scientific

16-717-8050

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Antigen:
IL-17A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
Q16552

Gene Symbols:
IL17A

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3605

Content And Storage:
4° C

Form:
Liquid

Applications:
Functional Assay, Immunostaining, Neutralization

Clone:
eBio64CAP17

Conjugate:
Functional Grade

Gene:
IL17A

Gene Alias:
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A

Host Species:
Mouse

Quantity:
50 mg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Invitrogen

16-721-182

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Antigen:
IL-21

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
Q9ES17

Gene Symbols:
IL21

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
60505

Content And Storage:
4° C

Form:
Liquid

Applications:
Functional Assay, Neutralization

Clone:
FFA21

Conjugate:
Functional Grade

Gene:
IL21

Gene Alias:
CVID11; CX2; il 21; IL21; IL-21; ILN; Interleukin; interleukin 21; Interleukin21; interleukin-21; interleukin-21 isoform; porcine interleukin-21; Za11

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Fischer Scientific

16-722-2025

--


Antigen:
IL-22

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
Q9GZX6, Q9JJY9

Gene Symbols:
IL22

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50616, 50929, 718047

Content And Storage:
4° C

Form:
Liquid

Applications:
Functional Assay, Neutralization

Clone:
IL22JOP

Conjugate:
Functional Grade

Gene:
IL22

Gene Alias:
Cytokine Zcyto18; EGK_03903; il 22; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL22; IL-22; Il22a; IL-22a; IL-D110; ILN; ILTIF; IL-TIF; ILTIF alpha; IL-TIF alpha; ILTIFa; Interleukin; interleukin 10-related T cell-derived inducible factor; interleukin 22; Interleukin22; interleukin-22; Interleukin-22a; RGD1561292; TIFa; TIFIL-23; UNQ3099/PRO10096; ZCYTO18

Host Species:
Rat

Quantity:
25 mg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Fischer Scientific

16-726-13005

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Gene:
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Quantity:
4/pk

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