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17-161-050UL

MilliporeSigma™ anti-Amyloid Precursor Protein, C-Terminal (751-770), Polyclonal

Manufacturer: MilliporeSigma™

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Pack Size	SKU	Availability	Price
Each of 1	17-161-050UL-Each-of-1	In Stock	₹ 44,937.88

17-161-050UL - Each of 1

₹ 44,937.88

In Stock

Quantity

Base Price: ₹ 44,937.88

GST (18%): ₹ 8,088.818

Total Price: ₹ 53,026.698

Antigen

Amyloid Precursor Protein, C-Terminal (751-770)

Classification

Polyclonal

Host Species

Rabbit

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Undiluted

Applications

Immunofluorescence, Immunohistochemistry, Immunoprecipitation

Conjugate

Unconjugated

Immunogen

a synthetic peptide [(C)KMQQNGYENPTYKFFEQMQN] corresponding to amino acids 751-770 of human precursor protein (APP), conjugated to KLH

Regulatory Status

RUO

Test Specificity

Recognizes full-length APP and C-terminal soluble products CTFγ (∽6kDa), CTFα (∽9kDa), and CTFβ (∽11kDa). Antibody Target Gene Symbol: APP Target Synonym: AAA, AD1, Adap, AL024401, Amyloid precursor, Amyloidogenic glycoprotein, APP isoform 1, APPI, appican, CTFgamma, CVAP, E030013M08RIK, Nexin II, P3, PN2, PreA4, PROTEASE NEXIN2 Entrez Gene Name: amyloid beta (A4) precursor protein

Content And Storage

−20°C

Isotype

IgG

Description

Specifically detects Amyloid Precursor Protein, C-Terminal (751-770) Clone: in Human samples, and it is validated for Immunofluorescence, Immunohistochemistry, Immunoprecipitation Amyloid precursor protein (APP) is a type I integral membrane protein with a large N-terminal extracellular domain, a single transmembrane domain, and a short cytoplasmic tail
APP is cleaved by alpha-secretase to generate sAPPα and CTFα, which is the C-terminal membrane, associated product ofα-secretase cleavage.α-secretase cleaves in the Aβ domain.β-secretase cleavage of APP at the N-terminal end of the Aβ sequence results in sAPPβ and CTFβ
Both CTFα and CTFβ are cleaved at the C-terminal end of the Aβ transmembrane domain to generate CTFγ
The antibody (171610) detects CTFγ fragment, which migrates at about 6kDa on SDS-PAGE gels.

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MilliporeSigma™

17-161-050UL

Antigen:

Amyloid Precursor Protein, C-Terminal (751-770)

Classification:

Polyclonal

Host Species:

Rabbit

Quantity:

50 μL

Primary or Secondary:

Primary

Target Species:

Human

Form:

Undiluted

Applications:

Immunofluorescence, Immunohistochemistry, Immunoprecipitation

Conjugate:

Unconjugated

Immunogen:

a synthetic peptide [(C)KMQQNGYENPTYKFFEQMQN] corresponding to amino acids 751-770 of human precursor protein (APP), conjugated to KLH

Regulatory Status:

RUO

Test Specificity:

Recognizes full-length APP and C-terminal soluble products CTFγ (∽6kDa), CTFα (∽9kDa), and CTFβ (∽11kDa). Antibody Target Gene Symbol: APP Target Synonym: AAA, AD1, Adap, AL024401, Amyloid precursor, Amyloidogenic glycoprotein, APP isoform 1, APPI, appican, CTFgamma, CVAP, E030013M08RIK, Nexin II, P3, PN2, PreA4, PROTEASE NEXIN2 Entrez Gene Name: amyloid beta (A4) precursor protein

Content And Storage:

−20°C

Isotype:

IgG

Fischer Scientific

17-161-1A

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Fischer Scientific

17-161-1C

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Haws™

17-161-3

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MilliporeSigma™ anti-Amyloid Precursor Protein, C-Terminal (751-770), Polyclonal

Select a Size

Select a Size

Properties

Antigen

Classification

Host Species

Quantity

Primary or Secondary

Target Species

Form

Applications

Conjugate

Immunogen

Regulatory Status

Test Specificity

Content And Storage

Isotype

Description

Compare Similar Items

Show Difference

MilliporeSigma™

Fischer Scientific

Antigen: __ Classification: __ Host Species: __ Quantity: __ Primary or Secondary: __ Target Species: __ Form: __ Applications: __ Conjugate: __ Immunogen: __ Regulatory Status: __ Test Specificity: __ Content And Storage: __ Isotype: __

Fischer Scientific

Antigen: __ Classification: __ Host Species: __ Quantity: __ Primary or Secondary: __ Target Species: __ Form: __ Applications: __ Conjugate: __ Immunogen: __ Regulatory Status: __ Test Specificity: __ Content And Storage: __ Isotype: __

Haws™

Antigen: __ Classification: __ Host Species: __ Quantity: __ Primary or Secondary: __ Target Species: __ Form: __ Applications: __ Conjugate: __ Immunogen: __ Regulatory Status: __ Test Specificity: __ Content And Storage: __ Isotype: __

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