20-486-91ML

MilliporeSigma™ anti-Complement 3, Polyclonal

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 20-486-91ML-Each-of-1 In Stock ₹ 16,372.76

20-486-91ML - Each of 1

₹ 16,372.76

In Stock

Quantity

1

Base Price: ₹ 16,372.76

GST (18%): ₹ 2,947.097

Total Price: ₹ 19,319.857

Antigen

Complement 3

Classification

Polyclonal

Formulation

Serum diluted in 500mM NaCl, 50mM Tris-HCl, pH 7.5.

Immunogen

purified, human C3 complement component

Regulatory Status

RUO

Test Specificity

Monospecific for C3 complement component. May also recognize C3 fragments, C3a, C3b, and C3c.

Content And Storage

−20°C

Isotype

IgG

Applications

Flow Cytometry, Immunoblot, Immunoblot, Immunocytochemistry, Immunoelectrophoresis

Conjugate

Unconjugated

Host Species

Goat

Quantity

1 mL

Primary or Secondary

Primary

Target Species

Baboon, Equine, Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat

Form

Undiluted

Related Products

Img

MilliporeSigma™

20-490-31MG

--

Img

MilliporeSigma™

56-519-11ML

--

Img

MilliporeSigma™

38-602-350UG

--

Img

MilliporeSigma™

57-477-850UL

--

Img

MilliporeSigma™

21-762-0100UG

--

Img

MilliporeSigma™

43-819-0100UG

--

Img

MilliporeSigma™

40-714-050UG

--

Img

MilliporeSigma™

21-766-0100UG

--

Description

  • Specifically detects Complement 3 Clone: in Baboon, Equine, Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat samples, and it is validated for Flow Cytometry, Immunocytochemistry, Immunoelectrophoresis, Immuno Blotting The complement system provides innate defense against microbial infection and is a complement to antibody mediated immunity
  • The complement system consists of thirty five interacting plasma and membrane associated proteins which contribute to host-defense and initiate and amplify inflammation, even in the preimmune state where specific antibodies and lymphocytes are not available
  • In addition to the complement components themselves, this system also contains several soluble factors that prevent spontaneous complement activation from occurring in solution, as well as, several regulatory membrane associated proteins that protect host cells from accidental complement attack
  • Cleavage of the C3 component by either the classical pathway or the alternative pathway releases C3a and C3b
  • C3a appears to be important in many inflammatory responses while the C3b fragment covalently binds to the cell or bacterial surface and plays a role in opsonisation
  • Binding of C3b to the C4b component of the C3 convertase, results in C5 convertase (C4b3b2a) formation.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

20-486-91ML

--


Antigen:
Complement 3

Classification:
Polyclonal

Formulation:
Serum diluted in 500mM NaCl, 50mM Tris-HCl, pH 7.5.

Immunogen:
purified, human C3 complement component

Regulatory Status:
RUO

Test Specificity:
Monospecific for C3 complement component. May also recognize C3 fragments, C3a, C3b, and C3c.

Content And Storage:
−20°C

Isotype:
IgG

Applications:
Flow Cytometry, Immunoblot, Immunoblot, Immunocytochemistry, Immunoelectrophoresis

Conjugate:
Unconjugated

Host Species:
Goat

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Baboon, Equine, Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat

Form:
Undiluted

Img

MilliporeSigma™

20-488-91ML

--


Antigen:
Complement 5a

Classification:
Polyclonal

Formulation:
Undiluted serum.

Immunogen:
__

Regulatory Status:
RUO

Test Specificity:
Monospecific for human C5a complement component as determined by OT.

Content And Storage:
−20°C

Isotype:
IgG

Applications:
ELISA, Immunoblot, Immunoblot

Conjugate:
Unconjugated

Host Species:
Rabbit

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Img

MilliporeSigma™

20-490-31MG

--


Antigen:
Complement 5b-9

Classification:
Polyclonal

Formulation:
In PBS, pH 7.2.

Immunogen:
purified human SC5b-9 complex

Regulatory Status:
RUO

Test Specificity:
Recognizes complement component complex Cb5-C9.

Content And Storage:
−20°C

Isotype:
IgG

Applications:
Immunodiffusion, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Rabbit

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Purified

Img

Fischer Scientific

20-501-15

--


Antigen:
__

Classification:
__

Formulation:
__

Immunogen:
__

Regulatory Status:
__

Test Specificity:
__

Content And Storage:
__

Isotype:
__

Applications:
__

Conjugate:
__

Host Species:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Form:
__