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200006793

CD45.1 Monoclonal Antibody (A20), Brilliant Violet™ 480, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD45.1

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias

B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, Leukocyte common antigen, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, PTPRC, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen

Gene Symbols

Ptprc

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Clone

A20

Applications

Flow Cytometry

Conjugate

Brilliant Violet 480

Host Species

Mouse

Target Species

Mouse

Gene Accession No.

P06800

Gene ID (Entrez)

19264

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Gene

Ptprc

Description

  • CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains
  • These CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells.

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Fischer Scientific

200006793

Mouse Monoclonal Antibody...

Antigen:
CD45.1
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, Leukocyte common antigen, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, PTPRC, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen
Gene Symbols:
Ptprc
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
A20
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 480
Host Species:
Mouse
Target Species:
Mouse
Gene Accession No.:
P06800
Gene ID (Entrez):
19264
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
Ptprc

Img

Fischer Scientific

200006795

Mouse Monoclonal Antibody...

Antigen:
CD45.1
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, Leukocyte common antigen, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, PTPRC, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen
Gene Symbols:
Ptprc
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
A20
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 711
Host Species:
Mouse
Target Species:
Mouse
Gene Accession No.:
P06800
Gene ID (Entrez):
19264
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
Ptprc

Img

Fischer Scientific

200006801

Rat Monoclonal Antibody...

Antigen:
IRF4
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
AI385587, interferon regulatory factor 4, Irf4, IRF-4, LSIRF, Lymphocyte-specific interferon regulatory factor, multiple myeloma oncogene 1, MUM1, NF-EM5, PU.1 interaction partner, Sfpi1/PU.1 interaction partner, SHEP8, Spip, Transcriptional activator PIP
Gene Symbols:
IRF4
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
3E4
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 480
Host Species:
Rat
Target Species:
Human, Mouse
Gene Accession No.:
Q15306, Q64287
Gene ID (Entrez):
16364, 3662
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Gene:
IRF4

Img

Fischer Scientific

200006801

Rat Monoclonal Antibody...

Antigen:
IRF4
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
AI385587, interferon regulatory factor 4, Irf4, IRF-4, LSIRF, Lymphocyte-specific interferon regulatory factor, multiple myeloma oncogene 1, MUM1, NF-EM5, PU.1 interaction partner, Sfpi1/PU.1 interaction partner, SHEP8, Spip, Transcriptional activator PIP
Gene Symbols:
IRF4
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
3E4
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 480
Host Species:
Rat
Target Species:
Human, Mouse
Gene Accession No.:
Q15306, Q64287
Gene ID (Entrez):
16364, 3662
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Gene:
IRF4