200006822

iNOS Monoclonal Antibody (CXNFT), Brilliant Violet™ 480, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

iNOS

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias

Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2

Gene Symbols

Nos2

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Clone

CXNFT

Applications

Flow Cytometry

Conjugate

Brilliant Violet 480

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P29477

Gene ID (Entrez)

18126

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Gene

Nos2

Description

  • iNOS (Inducible Nitric oxide, NO, NOS) is an inorganic, gaseous free radical that carries a variety of messages between cells
  • Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO
  • NO production is mediated by members of the nitric oxide synthase (NOS) family
  • iNOS is expressed in liver and inducible by a combination of lipopolysaccharide and certain cytokines
  • NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO
  • Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) and endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned
  • All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains
  • iNOS is found in a variety of cell types including macrophages, hepatocytes, synoviocytes, and smooth muscle cells
  • Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels
  • Protein kinase C-stimulating agents exhibit the same effect on iNOS activity
  • After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time
  • Three related iNOS pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17
  • Diseases associated with iNOS dysfunction include achalasia and impotence.

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Fischer Scientific

200006822

Rat Monoclonal Antibody...


Antigen:
iNOS

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2

Gene Symbols:
Nos2

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
CXNFT

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 480

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P29477

Gene ID (Entrez):
18126

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Gene:
Nos2

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Fischer Scientific

200006824

Rat Monoclonal Antibody...


Antigen:
iNOS

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2

Gene Symbols:
Nos2

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
CXNFT

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 786

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P29477

Gene ID (Entrez):
18126

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Gene:
Nos2

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200006825

Armenian Hamster Monoclonal Antibod...


Antigen:
CD3e

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
4930549J05Rik, A430104F18Rik, AI504783, antigen CD3D, delta polypeptide (TiT3 complex), antigen CD3E, epsilon polypeptide (TiT3 complex), antigen CD3G, gamma polypeptide, antigen CD3Z, zeta polypeptide, AW552088, Cd247, CD247 antigen, CD247 antigen, zeta subunit, Cd247 molecule, CD3, CD3 antigen delta chain, CD3 antigen delta polypeptide, CD3 antigen gamma chain, CD3 antigen, delta polypeptide, CD3 antigen, delta subunit, CD3 antigen, epsilon polypeptide, CD3 antigen, gamma polypeptide, CD3 antigen, zeta polypeptide, CD3 delta, CD3 epsilon, CD3 epsilon chain, CD3 epsilon subunit, CD3 epsilon subunit precursor, CD3 gamma-chain, CD3 glycoprotein, CD3 glycoprotein precursor, CD3 molecule delta polypeptide, CD3 molecule, delta, CD3 molecule, epsilon, CD3 molecule, epsilon polypeptide, CD3 molecule, gamma, CD3 molecule, gamma polypeptide, CD3 protein, CD3 TCR complex, CD3 type I transmembrane glycoprotein, CD3 type I transmembrane glycoprotein precursor, CD3 zeta chain, Cd3d, CD3D antigen delta, CD3D antigen, delta polypeptide (TiT3 complex), CD3d molecule, CD3d molecule, delta (CD3-TCR complex), CD3-DELTA, Cd3e, CD3E antigen, epsilon polypeptide, CD3E antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, CD3e molecule, epsilon (CD3-TCR complex), CD3epsilon, CD3-epsilon, Cd3-eta, Cd3g, CD3G antigen, gamma polypeptide, CD3g antigen, gamma polypeptide (TiT3 complex), CD3g molecule, CD3g molecule, epsilon (CD3-TCR complex), CD3g molecule, gamma (CD3-TCR complex), CD3-GAMMA, Cd3h, CD3Q, Cd3z, CD3Z antigen, zeta polypeptide (TiT3 complex), Cd3zeta, Cd3-zeta, CD3zeta chain, CD3-zeta/eta, Ctg3, Ctg-3, FLJ18683, IMD17, IMD18, IMD19, IMD25, Leu-4, OKT3, delta chain, T cell antigen receptor complex epsilon subunit of T3, T3/TCR complex, T3d, T3e, T3g, T3Z, T-cell antigen receptor complex, epsilon subunit of T3, T-cell antigen receptor complex, gamma subunit of T3, T-cell antigen receptor complex, zeta subunit of CD3, T-cell receptor CD3 epsilon chain, T-cell receptor CD3 epsilon subunit, T-cell receptor CD3 subunit zeta, T-cell receptor CD3, subunit zeta, T-cell receptor T3 delta chain, T-cell receptor T3 eta chain, T-cell receptor T3 gamma chain, T-cell receptor T3 zeta chain, T-cell receptor zeta chain, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 delta chain, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface glycoprotein CD3 gamma chain, T-cell surface glycoprotein CD3 zeta chain, T-cell surface protein, TcR CD3 delta-chain, TcR CD3 gamma-chain, TCR zeta chain, TCR zeta chain subunit, TCRE, Tcrk, TCRZ, TCRzeta, TiT3 complex, type I transmembrane protein, T-cell surface molecule CD3

Gene Symbols:
Cd247, Cd3d, CD3E, CD3g

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
145-2C11

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 605

Host Species:
Armenian Hamster

Target Species:
Mouse

Gene Accession No.:
P04235, P11942, P22646, P24161

Gene ID (Entrez):
12500, 12501, 12502, 12503

Isotype:
IgG

Purification Method:
Affinity chromatography

Gene:
__

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Fischer Scientific

200006826

Rat Monoclonal Antibody...


Antigen:
CD4

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
Activation B7-1 antigen, B7, B7.1, B7-1, BB1, B-lymphocyte activation antigen B7, CD28LG, CD28LG1, CD4, CD4 antigen, CD4 antigen (p55), CD4 antigen p55, Cd4 molecule, CD4 precursor, CD4 receptor, CD4, allele 1, cd4a, CD4mut, CD80, CD80 antigen (CD28 antigen ligand 1, B7-1 antigen), CD80 molecule, cell surface glycoprotein CD4, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, fCD4, L3T4, LAB7, Leu-3, Ly-4, lymphocyte antigen CD4, lymphocyte antigen CD4 precursor, membrane protein, p55, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4), T-lymphocyte activation antigen CD80, W3/25, W3/25 antigen

Gene Symbols:
CD4

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
GK1.5

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 395

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P06332

Gene ID (Entrez):
12504

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Gene:
CD4