200006833

CD19 Monoclonal Antibody (eBio1D3 (1D3)), Brilliant Violet™ 605, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD19

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias

AW495831, B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Cd19, CD19 antigen, CD19 molecule, CVID3, differentiation antigen CD19, Leu-12, T-cell surface antigen Leu-12

Gene Symbols

Cd19

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Clone

eBio1D3 (1D3)

Applications

Flow Cytometry

Conjugate

Brilliant Violet 605

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P25918

Gene ID (Entrez)

12478

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Gene

Cd19

Description

  • CD19 is a member of the immunoglobulin superfamily and has two Ig like domains
  • The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains
  • CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage
  • Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen
  • The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation, and is expressed in all B cell precursor leukemias
  • Lymphocytes proliferate and differentiate in response to various concentrations of different antigens
  • The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors
  • CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation
  • Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge
  • Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.

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Fischer Scientific

200006833

Rat Monoclonal Antibody...


Antigen:
CD19

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
AW495831, B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Cd19, CD19 antigen, CD19 molecule, CVID3, differentiation antigen CD19, Leu-12, T-cell surface antigen Leu-12

Gene Symbols:
Cd19

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
eBio1D3 (1D3)

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 605

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P25918

Gene ID (Entrez):
12478

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Gene:
Cd19

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200006834

Rat Monoclonal Antibody...


Antigen:
CD4

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
Activation B7-1 antigen, B7, B7.1, B7-1, BB1, B-lymphocyte activation antigen B7, CD28LG, CD28LG1, CD4, CD4 antigen, CD4 antigen (p55), CD4 antigen p55, Cd4 molecule, CD4 precursor, CD4 receptor, CD4, allele 1, cd4a, CD4mut, CD80, CD80 antigen (CD28 antigen ligand 1, B7-1 antigen), CD80 molecule, cell surface glycoprotein CD4, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, fCD4, L3T4, LAB7, Leu-3, Ly-4, lymphocyte antigen CD4, lymphocyte antigen CD4 precursor, membrane protein, p55, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4), T-lymphocyte activation antigen CD80, W3/25, W3/25 antigen

Gene Symbols:
CD4

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
GK1.5

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 605

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P06332

Gene ID (Entrez):
12504

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Gene:
CD4

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200006836

Rat Monoclonal Antibody...


Antigen:
CD62L (L-Selectin)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
A.11, AI528707, CD62 antigen-like family member L, CD62L, gp90-MEL, hLHRc, LAM1, LAM-1, LECAM1, LECAM-1, LEU8, Leu-8, Leukocyte adhesion molecule 1, leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHR, LSEL, L-selectin, Ly22, Ly-22, LYAM1, Lyam-1, Ly-m22, Lymph node homing receptor, lymphocyte adhesion molecule 1, lymphocyte antigen 22, Lymphocyte surface MEL-14 antigen, pln homing receptor, PLNHR, SELE, selectin E (endothelial adhesion molecule 1), selectin L, selectin L (lymphocyte adhesion molecule 1), selectin, lymphocyte, Sell, TQ1

Gene Symbols:
SELL

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
MEL-14

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 605

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P18337

Gene ID (Entrez):
20343

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Gene:
SELL

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200006839

Rabbit Recombinant Monoclonal Antib...


Antigen:
DYKDDDDK Tag

Concentration:
1.0 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Alias:
DDDDK, DDDDK epitope tag, ECS epitope tag, ECS tag, FLAG, FLAG Tag

Gene Symbols:
__

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
8H8L17

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Conjugate:
Alexa Fluor Plus 647

Host Species:
Rabbit

Target Species:
Tag

Gene Accession No.:
__

Gene ID (Entrez):
__

Isotype:
IgG

Purification Method:
Protein A

Gene:
__