200006841
CD45R (B220) Monoclonal Antibody (RA3-6B2), Brilliant Violet™ 605, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD45R (B220)
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen
Gene Symbols
PTPRC
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Clone
RA3-6B2
Applications
Flow Cytometry
Conjugate
Brilliant Violet 605
Host Species
Rat
Target Species
Human, Mouse
Gene Accession No.
P06800, P08575
Gene ID (Entrez)
19264, 5788
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Gene
PTPRC
Description
- CD45R (PTPRC) is a member of the protein tyrosine phosphatase (PTP) family
- PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
- CD45 contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains
- CD45 is specifically expressed in hematopoietic cells and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling
- CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
- CD45 protein exists in multiple isoforms as a result of alternative splicing, and these isoforms differ in their extracellular domains, but share identical transmembrane and cytoplasmic domains
- Further, these CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
- In addition to its role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
- CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
- Diseases associated with CD45 dysfunction include Severe Combined Immunodeficiency (T-cell negative, B-Cell Negative) and Hepatitis C.
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Antigen: CD45R (B220)
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen
Gene Symbols: PTPRC
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Clone: RA3-6B2
Applications: Flow Cytometry
Conjugate: Brilliant Violet 605
Host Species: Rat
Target Species: Human, Mouse
Gene Accession No.: P06800, P08575
Gene ID (Entrez): 19264, 5788
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: PTPRC
Antigen:
CD45R (B220)
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen
Gene Symbols:
PTPRC
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
RA3-6B2
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 605
Host Species:
Rat
Target Species:
Human, Mouse
Gene Accession No.:
P06800, P08575
Gene ID (Entrez):
19264, 5788
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
PTPRC
Antigen: TIGIT
Concentration: 1.0 mg/mL
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias: ENSMUSG00000071552, T cell immunoreceptor with Ig and ITIM domains, T-cell immunoreceptor with Ig and ITIM domains, TIGIT, V-set and immunoglobulin domain containing 9, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain containing 3, V-set and transmembrane domain-containing protein 3, VSIG9, VSTM3, Washington University cell adhesion molecule, WUCAM
Gene Symbols: TIGIT
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Clone: MBSA43
Applications: Flow Cytometry
Conjugate: Alexa Fluor Plus 555
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q495A1
Gene ID (Entrez): 201633
Isotype: IgG1 κ
Purification Method: Protein A/G
Gene: TIGIT
Antigen:
TIGIT
Concentration:
1.0 mg/mL
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias:
ENSMUSG00000071552, T cell immunoreceptor with Ig and ITIM domains, T-cell immunoreceptor with Ig and ITIM domains, TIGIT, V-set and immunoglobulin domain containing 9, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain containing 3, V-set and transmembrane domain-containing protein 3, VSIG9, VSTM3, Washington University cell adhesion molecule, WUCAM
Gene Symbols:
TIGIT
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
MBSA43
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor Plus 555
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q495A1
Gene ID (Entrez):
201633
Isotype:
IgG1 κ
Purification Method:
Protein A/G
Gene:
TIGIT
Antigen: TIGIT
Concentration: 1.0 mg/mL
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias: ENSMUSG00000071552, T cell immunoreceptor with Ig and ITIM domains, T-cell immunoreceptor with Ig and ITIM domains, TIGIT, V-set and immunoglobulin domain containing 9, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain containing 3, V-set and transmembrane domain-containing protein 3, VSIG9, VSTM3, Washington University cell adhesion molecule, WUCAM
Gene Symbols: TIGIT
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Clone: MBSA43
Applications: Flow Cytometry
Conjugate: Alexa Fluor Plus 555
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q495A1
Gene ID (Entrez): 201633
Isotype: IgG1 κ
Purification Method: Protein A/G
Gene: TIGIT
Antigen:
TIGIT
Concentration:
1.0 mg/mL
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias:
ENSMUSG00000071552, T cell immunoreceptor with Ig and ITIM domains, T-cell immunoreceptor with Ig and ITIM domains, TIGIT, V-set and immunoglobulin domain containing 9, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain containing 3, V-set and transmembrane domain-containing protein 3, VSIG9, VSTM3, Washington University cell adhesion molecule, WUCAM
Gene Symbols:
TIGIT
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
MBSA43
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor Plus 555
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q495A1
Gene ID (Entrez):
201633
Isotype:
IgG1 κ
Purification Method:
Protein A/G
Gene:
TIGIT
Antigen: TIGIT
Concentration: 1.0 mg/mL
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias: ENSMUSG00000071552, T cell immunoreceptor with Ig and ITIM domains, T-cell immunoreceptor with Ig and ITIM domains, TIGIT, V-set and immunoglobulin domain containing 9, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain containing 3, V-set and transmembrane domain-containing protein 3, VSIG9, VSTM3, Washington University cell adhesion molecule, WUCAM
Gene Symbols: TIGIT
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Clone: MBSA43
Applications: Flow Cytometry
Conjugate: Alexa Fluor Plus 555
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q495A1
Gene ID (Entrez): 201633
Isotype: IgG1 κ
Purification Method: Protein A/G
Gene: TIGIT
Antigen:
TIGIT
Concentration:
1.0 mg/mL
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias:
ENSMUSG00000071552, T cell immunoreceptor with Ig and ITIM domains, T-cell immunoreceptor with Ig and ITIM domains, TIGIT, V-set and immunoglobulin domain containing 9, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain containing 3, V-set and transmembrane domain-containing protein 3, VSIG9, VSTM3, Washington University cell adhesion molecule, WUCAM
Gene Symbols:
TIGIT
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
MBSA43
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor Plus 555
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q495A1
Gene ID (Entrez):
201633
Isotype:
IgG1 κ
Purification Method:
Protein A/G
Gene:
TIGIT